sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.624 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.619 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.584 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.575 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.563 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.546 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.529 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.528 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.527 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.518 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.508 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.494 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.489 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.489 | |
| 2bun | FAD | AppA protein | / | 0.488 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.484 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.483 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.482 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.481 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.481 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.481 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.479 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.478 | |
| 4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.478 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.477 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.476 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.474 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.472 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.472 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.471 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.469 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.469 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.469 | |
| 5cvc | PLP | Serine racemase | / | 0.469 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.467 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3a3b | RBF | Lumazine protein | / | 0.466 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.464 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.463 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4e2b | FMN | Dehydrogenase | / | 0.461 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4gub | 0Y4 | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2ejz | SAH | Diphthine synthase | / | 0.460 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.459 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.458 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.458 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 5cyo | GDP | Septin-9 | / | 0.457 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.456 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.455 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2cdu | ADP | NADH oxidase | / | 0.454 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.454 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.454 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.453 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.453 | |
| 4k5p | 1OS | M1 family aminopeptidase | 3.4.11 | 0.453 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.452 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.452 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.451 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.451 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.450 | |
| 2j8z | NAP | Quinone oxidoreductase PIG3 | 1 | 0.450 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.449 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.449 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.449 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.448 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.448 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.448 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.447 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.447 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.446 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.446 | |
| 2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.446 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.446 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.446 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.446 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.445 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.445 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3u9e | COA | Lmo1369 protein | / | 0.445 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 4gkm | 683 | Anthranilate phosphoribosyltransferase | / | 0.445 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.445 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.445 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1ppj | ANY | Cytochrome b | / | 0.444 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.444 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.444 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.444 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.443 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.443 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.443 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.443 | |
| 4ibm | IR1 | Insulin receptor | 2.7.10.1 | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.442 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.442 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.442 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.442 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.442 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.442 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.441 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.441 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2eka | SAH | Diphthine synthase | / | 0.440 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.440 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.440 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 |