sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 1.000 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.662 | |
| 2puh | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.599 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.530 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.527 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.512 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.511 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.507 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.506 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.504 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.503 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.501 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.501 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.499 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.498 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.497 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.496 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.495 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.495 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.495 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.494 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.493 | |
| 3b9l | AZZ | Serum albumin | / | 0.493 | |
| 2bxm | IMN | Serum albumin | / | 0.492 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.492 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.492 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.488 | |
| 3p9t | TCL | Repressor | / | 0.488 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
| 1ysx | 4EB | Serum albumin | / | 0.487 | |
| 2bxq | IMN | Serum albumin | / | 0.487 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.486 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.486 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.486 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.485 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.485 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.485 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.485 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.484 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.484 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.483 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.483 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.482 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.482 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.481 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.480 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.480 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.480 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.479 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.479 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.478 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.478 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.478 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.478 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.478 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.477 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.477 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.476 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 2xvw | 9NR | Serum albumin | / | 0.476 | |
| 3cse | N22 | Uncharacterized protein | / | 0.476 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.476 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.476 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.476 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.475 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.475 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.475 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.475 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.474 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.474 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 3eek | 53S | Uncharacterized protein | / | 0.473 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.473 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.473 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.472 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.472 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.472 | |
| 4apu | A2K | Progesterone receptor | / | 0.472 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.471 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.471 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.471 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.471 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.471 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.471 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.470 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.470 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.469 | |
| 2xvv | 9DN | Serum albumin | / | 0.469 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.469 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.469 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.469 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.469 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.469 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.469 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 3eel | 53T | Uncharacterized protein | / | 0.468 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.468 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.468 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.467 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.467 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.467 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.467 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.466 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.466 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.465 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2iog | IOG | Estrogen receptor | / | 0.464 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.464 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.463 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.463 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.463 | |
| 1wc0 | APC | Adenylate cyclase | / | 0.463 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.463 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.463 | |
| 3q99 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.463 | |
| 1eio | GCH | Gastrotropin | / | 0.462 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.462 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.462 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.462 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.462 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.461 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.461 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.461 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.461 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.461 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2acw | UPG | Glycosyltransferase | / | 0.460 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.460 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.460 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.460 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.460 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.459 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.459 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.459 | |
| 1kb9 | SMA | Cytochrome b | / | 0.458 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.458 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.458 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.458 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.458 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 2oal | FAD | Flavin-dependent tryptophan halogenase RebH | 1.14.19.9 | 0.457 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.457 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.457 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.457 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.456 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.456 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.456 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.456 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.456 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.456 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.456 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.455 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 3qly | 55V | Uncharacterized protein | / | 0.455 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.455 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.455 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.455 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.455 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.455 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.455 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.454 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4zas | TYD | CalS13 | / | 0.454 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.453 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2ay8 | 4TB | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.453 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.453 | |
| 3bej | MUF | Bile acid receptor | / | 0.453 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.453 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.453 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.452 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.452 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.452 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.452 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.452 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.451 | |
| 1k2s | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 1lrh | NLA | Auxin-binding protein 1 | / | 0.451 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.451 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.451 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.451 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.451 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.451 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.451 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.451 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 1mmv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.450 | |
| 3jt8 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 3tgu | WF3 | Cytochrome b | / | 0.450 | |
| 3v2u | ATP | Protein GAL3 | / | 0.450 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.450 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.450 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.449 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.449 | |
| 1onp | FOM | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.449 | |
| 1osv | CHC | Bile acid receptor | / | 0.449 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.449 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.449 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.449 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3jta | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.449 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.449 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1pp9 | SMA | Cytochrome b | / | 0.448 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.448 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.448 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.448 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.448 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.448 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.448 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3htj | ET | EbrA repressor | / | 0.448 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.448 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.448 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.448 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ezv | SMA | Cytochrome b | / | 0.447 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2bxo | OPB | Serum albumin | / | 0.447 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.447 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.447 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.447 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.447 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4jk4 | DIU | Serum albumin | / | 0.447 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.446 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.446 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.446 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.446 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.446 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.446 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3jt4 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.446 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.446 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.445 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.445 | |
| 2ibz | SMA | Cytochrome b | / | 0.445 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.445 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.445 | |
| 4fvx | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.445 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.445 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.445 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.444 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.444 | |
| 1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.444 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.444 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.444 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.444 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.444 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.444 | |
| 3h1j | SMA | Cytochrome b | / | 0.444 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.444 | |
| 4cx3 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3h18 | PMS | Esterase/lipase | / | 0.443 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.443 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.443 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.443 | |
| 4fvy | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.443 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.443 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1e7a | PFL | Serum albumin | / | 0.442 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.442 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 2ikf | UTP | Poly(A) polymerase, putative | / | 0.442 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.442 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.442 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.442 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.442 | |
| 3vw9 | HPJ | Lactoylglutathione lyase | 4.4.1.5 | 0.442 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.442 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4iah | 1DX | Alr2278 protein | / | 0.442 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4lb2 | DM5 | Serum albumin | / | 0.442 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 5agp | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.441 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.441 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.441 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.441 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2qjp | SMA | Cytochrome b | / | 0.441 | |
| 2qjy | SMA | Cytochrome b | / | 0.441 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.441 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.441 | |
| 4d1o | H4B | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.441 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.441 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.441 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.441 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.441 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1nde | MON | Estrogen receptor beta | / | 0.440 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.440 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 3eem | 53V | Uncharacterized protein | / | 0.440 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.440 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.440 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.440 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.440 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.440 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.440 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.440 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.440 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.440 | |
| 4xwt | U5P | Ribonuclease J | / | 0.440 | |
| 5ap5 | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.440 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |