sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2pb1	NFG	Glucan 1,3-beta-glucosidase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2pb1	NFG	Glucan 1,3-beta-glucosidase	/	1.000
1s4o	GDP	Glycolipid 2-alpha-mannosyltransferase	/	0.456
3gjw	GJW	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.456
2zsa	ADP	Pantothenate kinase	2.7.1.33	0.452
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
3gf4	UPG	UDP-galactopyranose mutase	5.4.99.9	0.445
2geu	COK	Pantothenate kinase	2.7.1.33	0.444
4b1e	6T6	Beta-secretase 1	3.4.23.46	0.442
4drj	RAP	Serine/threonine-protein kinase mTOR	2.7.11.1	0.440
4drj	RAP	Peptidyl-prolyl cis-trans isomerase FKBP4	5.2.1.8	0.440