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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2p9kATPActin-related protein 2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2p9kATPActin-related protein 2/1.000
4k41ATPActin, alpha skeletal muscle/0.555
4pl8ATPActin, alpha skeletal muscle/0.524
1s22ATPActin, alpha skeletal muscle/0.520
3eksATPActin-5C/0.520
4pkgATPActin, alpha skeletal muscle/0.520
4ci6ATPActin/0.518
1rgiATPActin, alpha skeletal muscle/0.517
1t44ATPActin, alpha skeletal muscle/0.517
3dawATPActin, alpha skeletal muscle/0.517
1qz5ATPActin, alpha skeletal muscle/0.512
3a5mATPMajor actin/0.509
3mn7ATPActin-5C/0.507
5ce3ATPActin/0.507
4cbxATPActin-2/0.506
3el2ATPActin-5C/0.503
1eqyATPActin, alpha skeletal muscle/0.502
1yxqATPActin, alpha skeletal muscle/0.501
2q36ATPActin, alpha skeletal muscle/0.498
1nmdATPMajor actin/0.495
4jhdANPActin-5C/0.495
4k43ADPActin, alpha skeletal muscle/0.485
3tu5ATPActin, alpha skeletal muscle/0.484
3ffkATPActin, alpha skeletal muscle/0.481
2oanATPActin, cytoplasmic 1/0.479
3u9dATPActin, alpha skeletal muscle/0.472
2q97ATPActin, alpha skeletal muscle/0.458
3uleATPActin-related protein 2/0.442