sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.518 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.480 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.477 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.476 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.462 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.457 | |
| 3tgp | GNP | GTPase HRas | / | 0.448 | |
| 4xvq | GNP | GTPase HRas | / | 0.447 | |
| 1vza | UMP | Thymidylate synthase | / | 0.445 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.442 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.440 |