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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2p1dSAHGenome polyprotein2.7.7.48

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2p1dSAHGenome polyprotein2.7.7.481.000
1l9kSAHGenome polyprotein2.7.7.480.735
1r6aSAHGenome polyprotein2.7.7.480.655
2p3qSAHGenome polyprotein/0.600
3eluSAMMethyltransferase/0.589
4ctjSAMGenome polyprotein/0.587
3eldSFGMethyltransferase/0.585
2pxaSAHGenome polyprotein2.7.7.480.584
3p8zSAHGenome polyprotein2.1.1.560.546
3elySAHMethyltransferase/0.540
5dtoSAHGenome polyprotein/0.539
3p97SAMGenome polyprotein2.1.1.560.531
5jjsSAHGenome polyprotein/0.520
5jjrSAHGenome polyprotein/0.518
4jrnANPRhoptry kinase family protein/0.514
2px5SAHGenome polyprotein2.7.7.480.512
3evbSAHGenome polyprotein2.1.1.560.511
2zjwREFCasein kinase II subunit alpha2.7.11.10.510
1ykdCMPAdenylate cyclase/0.507
3evaSAHGenome polyprotein2.1.1.560.506
2px2SAHGenome polyprotein2.7.7.480.505
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.499
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.498
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.498
2oxtSAMGenome polyprotein/0.495
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.491
5cuqNSCGenome polyprotein/0.490
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.489
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
4gk4L90Ephrin type-A receptor 32.7.10.10.484
3nga3NGCasein kinase II subunit alpha2.7.11.10.483
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
4g1wG1WMitogen-activated protein kinase 82.7.11.240.482
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.480
3gxlQIGTGF-beta receptor type-12.7.11.300.480
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
4n57ADPAPH(2'')-Id/0.479
1wvySTUDeath-associated protein kinase 12.7.11.10.478
3ez2ADPPlasmid partition protein A/0.478
3drcMTXDihydrofolate reductase1.5.1.30.477
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.477
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.477
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.476
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.476
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.476
2zbaZBATrichothecene 3-O-acetyltransferase/0.475
3s7a684Dihydrofolate reductase1.5.1.30.475
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.475
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.474
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.473
2x9fX9FEphrin type-B receptor 42.7.10.10.473
4y93746Tyrosine-protein kinase/0.473
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.472
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.472
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.472
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.472
1zrzBI1Protein kinase C iota type2.7.11.130.471
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.471
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4btjATPTau-tubulin kinase 12.7.11.10.471
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.470
2w9hTOPDihydrofolate reductase1.5.1.30.470
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.470
4j97ACPFibroblast growth factor receptor 2/0.470
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.469
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.469
1pd9CO4Dihydrofolate reductase1.5.1.30.468
2bi4NADLactaldehyde reductase1.1.1.770.468
2bl4NADLactaldehyde reductase1.1.1.770.468
3dogNNNCyclin-dependent kinase 22.7.11.220.468
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.468
4cfnJYMCyclin-dependent kinase 22.7.11.220.468
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.468
1s6qTPBGag-Pol polyprotein2.7.7.490.467
2itqITQEpidermal growth factor receptor2.7.10.10.467
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.467
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.467
4jia1K3Tyrosine-protein kinase JAK2/0.467
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.467
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.466
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.466
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.465
2csnCKICasein kinase I homolog 12.7.11.10.465
2hog710Serine/threonine-protein kinase Chk12.7.11.10.465
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.465
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.465
4aotGW8Serine/threonine-protein kinase 102.7.11.10.465
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.465
1rkhVD2Vitamin D3 receptor/0.464
1k6pXN3Gag-Pol polyprotein3.4.23.160.463
1og5SWFCytochrome P450 2C9/0.463
2bxmIMNSerum albumin/0.463
2np8CC3Aurora kinase A2.7.11.10.463
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3zsi52PMitogen-activated protein kinase 14/0.463
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4jlm1NNDeoxycytidine kinase2.7.1.740.463
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.463
1diuBDMDihydrofolate reductase1.5.1.30.462
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.462
4ly91YYGlucokinase regulatory protein/0.462
4x5gFOLDihydrofolate reductase1.5.1.30.462
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1rx1NAPDihydrofolate reductase1.5.1.30.461
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2p15EZTEstrogen receptor/0.461
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.461
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.461
3nj0PYVAbscisic acid receptor PYL2/0.461
4bb3KKAIsopenicillin N synthase1.21.3.10.461
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4ie5MD6Alpha-ketoglutarate-dependent dioxygenase FTO/0.461
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.461
1dr3TAPDihydrofolate reductase1.5.1.30.460
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3b1jNADGlyceraldehyde-3-phosphate dehydrogenase/0.460
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4jrvKJVEpidermal growth factor receptor2.7.10.10.460
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.460
1dhiMTXDihydrofolate reductase1.5.1.30.459
1hfqMOTDihydrofolate reductase1.5.1.30.459
1rrmAPRLactaldehyde reductase1.1.1.770.459
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.459
4a61ANPPlasmid segregation protein ParM/0.459
4an4DUDPutative glycosyl transferase/0.459
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.459
4nc3ERM5-hydroxytryptamine receptor 2B/0.459
4ocvANPAminoglycoside phosphotransferase/0.459
1hk5T44Serum albumin/0.458
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.458
2ghlLIBMitogen-activated protein kinase 14/0.458
2iviACWIsopenicillin N synthase1.21.3.10.458
3a292T0Fructose-1,6-bisphosphatase 13.1.3.110.458
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
3nszANPCasein kinase II subunit alpha2.7.11.10.458
3tn8F18Cyclin-dependent kinase 92.7.11.220.458
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1m78NDPDihydrofolate reductase1.5.1.30.457
1obnASVIsopenicillin N synthase1.21.3.10.457
1rx8NAPDihydrofolate reductase1.5.1.30.457
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.457
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.457
2wotZZGTGF-beta receptor type-12.7.11.300.457
4e730NRMitogen-activated protein kinase 82.7.11.240.457
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.457
4hyu1BKMitogen-activated protein kinase 82.7.11.240.457
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.457
5auwQUEDeath-associated protein kinase 12.7.11.10.457
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.456
1wvxBD4Death-associated protein kinase 12.7.11.10.456
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.456
2x6dX6DAurora kinase A2.7.11.10.456
3d84NDPDihydrofolate reductase1.5.1.30.456
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4ap1NAPSteroid monooxygenase/0.456
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.456
4ivw1GJEstrogen receptor/0.456
4k8aK8AFocal adhesion kinase 12.7.10.20.456
1bk0ACVIsopenicillin N synthase1.21.3.10.455
1s4eADPGalactokinase/0.455
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
2vcmM11Isopenicillin N synthase1.21.3.10.455
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.455
3own3OWRenin3.4.23.150.455
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.455
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
5kf2COAPredicted acetyltransferase/0.455
2ejvNADL-threonine 3-dehydrogenase/0.454
2fziDH3Dihydrofolate reductase1.5.1.30.454
2iw84SPCyclin-dependent kinase 22.7.11.220.454
2wo7ASVIsopenicillin N synthase1.21.3.10.454
3a6rFMNFMN-binding protein/0.454
3rvg17PTyrosine-protein kinase JAK2/0.454
3w9rA8SAbscisic acid receptor PYL9/0.454
5dn3ATPAurora kinase A2.7.11.10.454
1blzACVIsopenicillin N synthase1.21.3.10.453
1f28UMPThymidylate synthase2.1.1.450.453
1k6tXN1Gag-Pol polyprotein3.4.23.160.453
1qknRALEstrogen receptor beta/0.453
1s3uTQDDihydrofolate reductase1.5.1.30.453
1sn0T44Transthyretin/0.453
3ddw055Glycogen phosphorylase, liver form2.4.1.10.453
3h4vDVPPteridine reductase 11.5.1.330.453
3vt5YI2Vitamin D3 receptor/0.453
3vt8YI3Vitamin D3 receptor/0.453
4gmy0X5Tyrosine-protein kinase JAK2/0.453
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.453
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.453
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.453
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.453
1msmJE2Gag-Pol polyprotein3.4.23.160.452
1mvsDTMDihydrofolate reductase1.5.1.30.452
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1v0oINRCell division control protein 2 homolog2.7.11.220.452
1y9dTPPPyruvate oxidase1.2.3.30.452
1yinCM3Estrogen receptor/0.452
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2h96893Mitogen-activated protein kinase 82.7.11.240.452
2hqpNDPDihydrofolate reductase1.5.1.30.452
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.452
2pwlACPFibroblast growth factor receptor 2/0.452
3uvp048Mitogen-activated protein kinase 14/0.452
4b8lA0PAurora kinase B-A2.7.11.10.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.451
2p4yC03Peroxisome proliferator-activated receptor gamma/0.451
2r43G3GGag-Pol polyprotein3.4.23.160.451
3eljGS7Mitogen-activated protein kinase 82.7.11.240.451
3nmpPYVAbscisic acid receptor PYL2/0.451
3uwqU5POrotidine 5'-phosphate decarboxylase/0.451
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.451
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4awq592Heat shock protein HSP 90-alpha/0.451
4bcmT7ZCyclin-dependent kinase 22.7.11.220.451
4eqwCOACoenzyme A disulfide reductase/0.451
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
1g6cIFPThiamine-phosphate synthase/0.450
2vbdV10Isopenicillin N synthase1.21.3.10.450
2vbpVB1Isopenicillin N synthase1.21.3.10.450
3bgbLJGGag-Pol polyprotein3.4.23.160.450
4izy1J2Mitogen-activated protein kinase 82.7.11.240.450
4uxxACPDiacylglycerol kinase2.7.1.1070.450
4wa9AXITyrosine-protein kinase ABL12.7.10.20.450
4xj43ATCyclic GMP-AMP synthase/0.450
1bsvNDPGDP-L-fucose synthase/0.449
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.449
1pl8NADSorbitol dehydrogenase1.1.1.140.449
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.449
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.449
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.449
2hcdBIVVitamin D3 receptor A/0.449
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.449
2xuuADPDeath-associated protein kinase 12.7.11.10.449
2y6o1N1Ephrin type-A receptor 42.7.10.10.449
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.449
3r9hZ67Cyclin-dependent kinase 22.7.11.220.449
4hvi19STyrosine-protein kinase JAK32.7.10.20.449
4o1pANPRibonuclease L/0.449
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.449
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
5av2KMPDeath-associated protein kinase 12.7.11.10.449
5awmANPStress-activated protein kinase JNK2.7.11.240.449
1axwMTXThymidylate synthase/0.448
1hquHBYGag-Pol polyprotein2.7.7.490.448
1oiyN41Cyclin-dependent kinase 22.7.11.220.448
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1uadGNPRas-related protein Ral-A/0.448
2ag1TPPBenzaldehyde lyase/0.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2rhrEMOPutative ketoacyl reductase1.3.10.448
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.448
3ertOHTEstrogen receptor/0.448
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.448
3hz142CHeat shock protein HSP 90-alpha/0.448
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
3oafOAGDihydrofolate reductase1.5.1.30.448
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.448
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3wv9FEGHmd co-occurring protein HcgE/0.448
4azmT4BFatty acid-binding protein, epidermal/0.448
4c57FEFCyclin-G-associated kinase2.7.11.10.448
4g95OAGDihydrofolate reductase1.5.1.30.448
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.448
4m4922YL-lactate dehydrogenase A chain1.1.1.270.448
4nks2M2Fibroblast growth factor receptor 1/0.448
5drdATPAurora kinase A2.7.11.10.448
5k2aZMAAdenosine receptor A2a/0.448
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.447
1mbtFADUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.447
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
2eb3ANPEpidermal growth factor receptor2.7.10.10.447
2p33J07Mitogen-activated protein kinase 102.7.11.240.447
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3h4vNAPPteridine reductase 11.5.1.330.447
3iok1P6Tyrosine-protein kinase JAK2/0.447
3lanKBTGag-Pol polyprotein2.7.7.490.447
4ejmNAPPutative zinc-binding dehydrogenase/0.447
4hni16WCasein kinase I isoform epsilon2.7.11.10.447
4ie0PD2Alpha-ketoglutarate-dependent dioxygenase FTO/0.447
4ienCOAPutative acyl-CoA hydrolase/0.447
4jq7KJQEpidermal growth factor receptor2.7.10.10.447
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.447
4lj3C2ECyclic di-GMP phosphodiesterase YahA3.1.40.447
4rh10TTSpore photoproduct lyase/0.447
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.447
5dt3ATPAurora kinase A2.7.11.10.447
5l7dCLRSmoothened homolog/0.447
1i44ACPInsulin receptor2.7.10.10.446
1pkdUCNCyclin-dependent kinase 22.7.11.220.446
2btsU32Cyclin-dependent kinase 22.7.11.220.446
2npnSAMPutative cobalamin synthesis related protein/0.446
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.446
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.446
2ydwWSHBromodomain-containing protein 2/0.446
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3d7tSTUTyrosine-protein kinase CSK/0.446
3gwfNAPCyclohexanone monooxygenase/0.446
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3ns2PYVAbscisic acid receptor PYL2/0.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.446
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
5l8jADPAurora kinase A2.7.11.10.446
1bxsNADRetinal dehydrogenase 11.2.1.360.445
1dr2TAPDihydrofolate reductase1.5.1.30.445
1dr3HBIDihydrofolate reductase1.5.1.30.445
1klkPMDDihydrofolate reductase1.5.1.30.445
1np7FADCryptochrome DASH/0.445
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2vmyFFOSerine hydroxymethyltransferase/0.445
2y5s78HDihydropteroate synthase/0.445
3a8tATPAdenylate isopentenyltransferase/0.445
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.445
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.445
4c9pCAMCytochrome P450/0.445
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.445
4fvqATPTyrosine-protein kinase JAK2/0.445
4g8zTOPDihydrofolate reductase1.5.1.30.445
4ia1BIVVitamin D3 receptor A/0.445
4l17DNQGlutamate receptor 2/0.445
4nbwNADShort-chain dehydrogenase/reductase SDR/0.445
5av3KMPDeath-associated protein kinase 12.7.11.10.445
5e8wSTUTGF-beta receptor type-12.7.11.300.445
1e92HBIPteridine reductase 11.5.1.330.444
1i5aACPChemotaxis protein CheA2.7.13.30.444
1u3dFADCryptochrome-1/0.444
1wbpADPSRSF protein kinase 12.7.11.10.444
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.444
2iogIOGEstrogen receptor/0.444
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.444
2zaxCAMCamphor 5-monooxygenase1.14.15.10.444
3cgfJNFMitogen-activated protein kinase 102.7.11.240.444
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.444
3cvuFADRE11660p/0.444
3o3pGDDGlycosyl transferase, family 2/0.444
3qihFG7Gag-Pol polyprotein3.4.23.160.444
3tnwF18Cyclin-dependent kinase 22.7.11.220.444
3vrwYS5Vitamin D3 receptor/0.444
4c4h7RODual specificity protein kinase TTK2.7.12.10.444
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.444
4g1z0VPVitamin D3 receptor A/0.444
4iae1DXAlr2278 protein/0.444
4k6fNAPPutative Acetoacetyl-CoA reductase/0.444
4lsl1YQGag-Pol polyprotein2.7.7.490.444
1ia4TQ6Dihydrofolate reductase1.5.1.30.443
1l2jETCEstrogen receptor beta/0.443
1ol5ADPAurora kinase A2.7.11.10.443
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
2i40BLZCyclin-dependent kinase 22.7.11.220.443
2rf2MRXGag-Pol polyprotein2.7.7.490.443
2z3uCRRCytochrome P450/0.443
2zlaVDBVitamin D3 receptor/0.443
3bw2FMNPutative 2-nitropropane dioxygenase/0.443
3c4xATPRhodopsin kinase/0.443
3cwkREACellular retinoic acid-binding protein 2/0.443
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.443
3qly55VUncharacterized protein/0.443
3vt7VDXVitamin D3 receptor/0.443
4cd2FOLDihydrofolate reductase1.5.1.30.443
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.443
4jqeANPCasein kinase II subunit alpha2.7.11.10.443
4l0qNADAlcohol dehydrogenase class-3/0.443
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.443
4xz3COAAcyl-CoA synthetase (NDP forming)/0.443
5cyqT27Gag-Pol polyprotein2.7.7.490.443
1db1VDXVitamin D3 receptor/0.442
1ezvUQ6Cytochrome b/0.442
1hk4T44Serum albumin/0.442
1pjkANPCasein kinase II subunit alpha2.7.11.10.442
1qjfACSIsopenicillin N synthase1.21.3.10.442
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.442
1vyw292Cyclin-dependent kinase 22.7.11.220.442
2baqPQBMitogen-activated protein kinase 14/0.442
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.442
2fszOHTEstrogen receptor beta/0.442
2henADPEphrin type-B receptor 22.7.10.10.442
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.442
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2y60M8FIsopenicillin N synthase1.21.3.10.442
3cseN22Uncharacterized protein/0.442
3hz137DHeat shock protein HSP 90-alpha/0.442
3pxkPXKFocal adhesion kinase 12.7.10.20.442
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.442
4ez50RSCyclin-dependent kinase 62.7.11.220.442
4i8vBHFCytochrome P450 1A11.14.14.10.442
5a3cNADSIR2 family protein/0.442
1di8DTQCyclin-dependent kinase 22.7.11.220.441
1jpaANPEphrin type-B receptor 22.7.10.10.441
1m17AQ4Epidermal growth factor receptor2.7.10.10.441
1pxpCK8Cyclin-dependent kinase 22.7.11.220.441
1q1rFADPutidaredoxin reductase1.18.1.50.441
1rx7FOLDihydrofolate reductase1.5.1.30.441
1yvj4STTyrosine-protein kinase JAK32.7.10.20.441
2bfpH4BPteridine reductase 11.5.1.330.441
2bujSTUSerine/threonine-protein kinase 16/0.441
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.441
2pupADPMethylthioribose kinase2.7.1.1000.441
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.441
2vwu7X1Ephrin type-B receptor 42.7.10.10.441
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.441
2ylzFADPhenylacetone monooxygenase1.14.13.920.441
3bhy7CPDeath-associated protein kinase 3/0.441
3ibqATPPyridoxal kinase/0.441
3vt65YIVitamin D3 receptor/0.441
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.441
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4ig3T27Gag-Pol polyprotein2.7.7.490.441
4jqlVJ6Heat shock protein HSP 90-alpha/0.441
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.441
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4xgxADPFAD:protein FMN transferase/0.441
1cbsREACellular retinoic acid-binding protein 2/0.440
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.440
1j39UPGDNA beta-glucosyltransferase/0.440
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
1ny5ADPTranscriptional regulator (NtrC family)/0.440
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
1uy7PU4Heat shock protein HSP 90-alpha/0.440
1y6bAAXVascular endothelial growth factor receptor 22.7.10.10.440
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2bmcMPYAurora kinase A2.7.11.10.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2o4rVD5Vitamin D3 receptor/0.440
2ohvNHLGlutamate racemase/0.440
2w3wVG9Dihydrofolate reductase/0.440
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.440
2xs0ANPMitogen-activated protein kinase 82.7.11.240.440
3kpzZNEVitamin D3 receptor/0.440
3nxxNDPDihydrofolate reductase1.5.1.30.440
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qihNI7Gag-Pol polyprotein3.4.23.160.440
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.440
3w5rLOAVitamin D3 receptor/0.440
4eol1ROCyclin-dependent kinase 22.7.11.220.440
4fweFADLysine-specific histone demethylase 1B10.440
4h9506UDihydrofolate reductase1.5.1.30.440
4hgt15GCasein kinase I isoform delta2.7.11.10.440
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.440
5e92ANPTGF-beta receptor type-22.7.11.300.440