Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ozo | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2ozo | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 1.000 | |
| 4k2r | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.632 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.625 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.617 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.541 | |
| 3p23 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.538 | |
| 3pls | ANP | Macrophage-stimulating protein receptor | 2.7.10.1 | 0.529 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.526 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.526 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.526 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.525 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.522 | |
| 5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.521 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.519 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.519 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.519 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.518 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.517 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.516 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.514 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.514 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.512 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.509 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.509 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.508 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.507 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.507 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.507 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.506 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.506 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.506 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.505 | |
| 1pxo | CK7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.501 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.500 | |
| 3c4w | ATP | Rhodopsin kinase | / | 0.500 | |
| 3c4z | ADP | Rhodopsin kinase | / | 0.500 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.500 | |
| 3vn9 | ANK | Dual specificity mitogen-activated protein kinase kinase 6 | 2.7.12.2 | 0.499 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.498 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.497 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.497 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.496 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.496 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.495 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.495 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.494 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.494 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.494 | |
| 2z7q | ACP | Ribosomal protein S6 kinase alpha-1 | 2.7.11.1 | 0.493 | |
| 3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.493 | |
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 0.492 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.492 | |
| 4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.492 | |
| 3orp | AGS | Serine/threonine protein kinase | / | 0.491 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.491 | |
| 4c3p | ACP | Aurora kinase A | 2.7.11.1 | 0.491 | |
| 1b39 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 1hck | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.489 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.489 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.489 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.488 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.488 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.488 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.488 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.486 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.486 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.486 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.486 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.484 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.484 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.484 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.484 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.483 | |
| 2w4j | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.483 | |
| 3cok | ANP | Serine/threonine-protein kinase PLK4 | 2.7.11.21 | 0.483 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.482 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.482 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.481 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2c6l | DT4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.479 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.478 | |
| 2o2u | 738 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.478 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 3kmw | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.477 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.476 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.476 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.475 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.474 | |
| 2ji7 | OXT | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.474 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.474 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.474 | |
| 4o0u | ADN | Aurora kinase A | 2.7.11.1 | 0.474 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.473 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.473 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3wdl | ATP | 4-phosphopantoate--beta-alanine ligase | 6.3.2.36 | 0.473 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.472 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.472 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.472 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.471 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.470 | |
| 4b8l | A0P | Aurora kinase B-A | 2.7.11.1 | 0.470 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.470 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.470 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.470 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.470 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.469 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.469 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.469 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.469 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.469 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.468 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1jkk | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.467 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.467 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.467 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.466 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.466 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.466 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.466 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.466 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.465 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.464 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.464 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.464 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.463 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.463 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.463 | |
| 4dta | ADN | APH(2'')-Id | / | 0.463 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.463 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.462 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.462 | |
| 3ztx | ZTX | Aurora kinase B-A | 2.7.11.1 | 0.462 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.462 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.461 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.461 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.461 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 4mk0 | 29X | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.461 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.461 | |
| 1pkg | ADP | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.460 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.460 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.460 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.460 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.459 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 1w8c | N69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2bmc | MPY | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2yxl | SFG | 450aa long hypothetical fmu protein | / | 0.458 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 4s33 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.458 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.457 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.457 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.457 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.457 | |
| 4gfg | 0XF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.457 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.457 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.456 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.456 | |
| 2ji6 | OXK | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.456 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2x4f | 16X | Myosin light chain kinase family member 4 | 2.7.11.1 | 0.456 | |
| 3g51 | ANP | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.456 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.456 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 4ceg | ADP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.455 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2zoq | 5ID | Mitogen-activated protein kinase 3 | 2.7.11.24 | 0.455 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.455 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 4l03 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.454 | |
| 2fzg | CTP | Aspartate carbamoyltransferase regulatory chain | / | 0.454 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2zmd | 537 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.454 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.454 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.453 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3tm0 | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.453 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 2r3r | 6SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.452 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4j99 | ACP | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.452 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.451 | |
| 1ja1 | NAP | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 2bkk | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.451 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2r3i | SCF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.451 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.451 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.451 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3vqv | ANP | Pyrrolysine--tRNA ligase | / | 0.451 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.451 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.450 | |
| 1u7w | CTP | Coenzyme A biosynthesis bifunctional protein CoaBC | 6.3.2.5 | 0.450 | |
| 1vh3 | CMK | 3-deoxy-manno-octulosonate cytidylyltransferase | 2.7.7.38 | 0.450 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.450 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 4b0g | VEK | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.450 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.450 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.450 | |
| 4y12 | AGS | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.450 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.449 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3lu6 | IMX | Serum albumin | / | 0.449 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.449 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.448 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.448 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.448 | |
| 3lnv | 1ZZ | Saframycin Mx1 synthetase B | / | 0.448 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.448 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.448 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.448 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.447 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.447 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.447 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.446 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.446 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.446 | |
| 3qfr | NAP | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.446 | |
| 4jik | 1KO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.446 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.446 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2xzw | ATP | Nitrogen regulatory protein P-II | / | 0.445 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.445 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.445 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.445 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.445 | |
| 4la0 | 198 | Serum albumin | / | 0.445 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 1hk5 | T44 | Serum albumin | / | 0.444 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2ji8 | FYN | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2zxg | S23 | Aminopeptidase N | 3.4.11.2 | 0.444 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.444 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1sez | OMN | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.443 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.443 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 3ea0 | ATP | ATPase, ParA family | / | 0.443 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.443 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.443 | |
| 4ffm | ADP | Uncharacterized protein | / | 0.443 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.442 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.442 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.442 | |
| 2bun | FAD | AppA protein | / | 0.442 | |
| 2bx8 | AZQ | Serum albumin | / | 0.442 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2wgh | DTP | Ribonucleoside-diphosphate reductase large subunit | 1.17.4.1 | 0.442 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.442 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.442 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 2gn4 | UD1 | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.441 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3orl | AGS | Serine/threonine protein kinase | / | 0.441 | |
| 3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3rbv | NAP | Sugar 3-ketoreductase | / | 0.441 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4bi0 | Z0W | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.441 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1hk1 | T44 | Serum albumin | / | 0.440 | |
| 1kqm | ANP | Myosin heavy chain, striated muscle | / | 0.440 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.440 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2vts | LZC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.440 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.440 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vqx | BLK | Pyrrolysine--tRNA ligase | / | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.440 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.440 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |