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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2oyuIMSProstaglandin G/H synthase 11.14.99.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2oyuIMSProstaglandin G/H synthase 11.14.99.11.000
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.580
3kk6CELProstaglandin G/H synthase 11.14.99.10.546
4coxIMNProstaglandin G/H synthase 21.14.99.10.522
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.517
3ln1CELProstaglandin G/H synthase 21.14.99.10.516
3rr3FLRProstaglandin G/H synthase 21.14.99.10.502
3n8wFLPProstaglandin G/H synthase 11.14.99.10.496
4otyLURProstaglandin G/H synthase 21.14.99.10.492
5ikrID8Prostaglandin G/H synthase 21.14.99.10.492
1ht834CProstaglandin G/H synthase 11.14.99.10.482
3mqe416Prostaglandin G/H synthase 21.14.99.10.477
3ntgD72Prostaglandin G/H synthase 21.14.99.10.474
4rrwLURProstaglandin G/H synthase 21.14.99.10.474
4rrzLURProstaglandin G/H synthase 21.14.99.10.474
1q4gBFLProstaglandin G/H synthase 11.14.99.10.464
3n8zFLPProstaglandin G/H synthase 11.14.99.10.464
1eqhFLPProstaglandin G/H synthase 11.14.99.10.462
1eqgIBPProstaglandin G/H synthase 11.14.99.10.455
3n8xNIMProstaglandin G/H synthase 11.14.99.10.452
3n8yDIFProstaglandin G/H synthase 11.14.99.10.443