sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2opx	DXC	Lactaldehyde dehydrogenase	1.2.1.22

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2opx	DXC	Lactaldehyde dehydrogenase	1.2.1.22	1.000
3nwl	NDP	Catalase	1.11.1.6	0.472
1rkp	IBM	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.455
4ddl	0JQ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.455
4y6n	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.450
2wey	EV1	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
3bjc	WAN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.449
1uwz	THU	Cytidine deaminase	3.5.4.5	0.446
4ajd	F04	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.441
2oal	FAD	Flavin-dependent tryptophan halogenase RebH	1.14.19.9	0.440