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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ol0DUDDUTP pyrophosphatase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2ol0DUDDUTP pyrophosphatase/1.000
4wrkDUPDUTPase/0.576
2okeDUPDUTP pyrophosphatase/0.556
3h06VBPGlutamate receptor 2/0.513
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.507
1bil0IURenin3.4.23.150.502
1rx8NAPDihydrofolate reductase1.5.1.30.502
1vi2NADQuinate/shikimate dehydrogenase/0.500
2il2LIXRenin3.4.23.150.500
3k8q22APurine nucleoside phosphorylase2.4.2.10.500
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.497
2iko7IGRenin3.4.23.150.496
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.496
1dgmADNAdenosine kinase2.7.1.200.495
1vgrCOAFormyl-CoA:oxalate CoA-transferase/0.495
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.495
4bfvZVVPantothenate kinase2.7.1.330.495
1j49NADD-lactate dehydrogenase1.1.1.280.494
1pd9CO4Dihydrofolate reductase1.5.1.30.494
2g1n1IGRenin3.4.23.150.493
1kp2ATPArgininosuccinate synthase6.3.4.50.492
2g1y5IGRenin3.4.23.150.491
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.491
3fpjSAMUncharacterized protein/0.491
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.491
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2g247IGRenin3.4.23.150.490
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.490
4jtqNAPAldo-keto reductase family 1 member C2/0.490
1udaUFGUDP-glucose 4-epimerase5.1.3.20.489
3clsFADElectron transfer flavoprotein subunit alpha/0.489
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.489
3t4eNADQuinate/shikimate dehydrogenase/0.489
4a802ANMajor pollen allergen Bet v 1-A/0.489
1h51FMNPentaerythritol tetranitrate reductase/0.488
4qaiFMNNADPH dehydrogenase/0.488
3q43D66M1 family aminopeptidase3.4.110.487
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.486
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.485
1nhhANPDNA mismatch repair protein MutL/0.485
1o9bNAIQuinate/shikimate dehydrogenase/0.485
2gsdNADFormate dehydrogenase/0.485
2ylzFADPhenylacetone monooxygenase1.14.13.920.485
4an4DUDPutative glycosyl transferase/0.485
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.485
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.485
3fhxPLPPyridoxal kinase2.7.1.350.484
4cfaWOPIntegrase/0.484
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.484
3cluFADElectron transfer flavoprotein subunit alpha/0.483
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.483
4wudANPDNA gyrase subunit B/0.483
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.482
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.482
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.482
4rvnCOAPhenylacetate-coenzyme A ligase/0.482
1xe65FPPlasmepsin-23.4.23.390.481
2c29NAPDihydroflavonol 4-reductase/0.481
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.481
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.481
1u2yGOXPancreatic alpha-amylase/0.480
1umaIN2Prothrombin3.4.21.50.480
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.480
4fxy0W2Neurolysin, mitochondrial3.4.24.160.480
1hkuNADC-terminal-binding protein 11.1.10.479
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.479
3t70DU4Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.479
4bfwZVWPantothenate kinase2.7.1.330.479
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.479
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
7stdCRPScytalone dehydratase4.2.1.940.479
1xelUPGUDP-glucose 4-epimerase5.1.3.20.478
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.478
3atyFMNProstaglandin F2a synthase/0.478
3vyfVYFRenin3.4.23.150.478
3zv7NHGAcetylcholinesterase3.1.1.70.478
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.478
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.477
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.477
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.477
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1xs7MMIBeta-secretase 13.4.23.460.476
2cmoM1LGlutamate receptor 2/0.476
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.476
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.476
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.475
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.475
3sn6P0GBeta-2 adrenergic receptor/0.475
1xddAAYIntegrin alpha-L/0.474
2b3vACODiamine acetyltransferase 1/0.474
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.474
2j3qTFLAcetylcholinesterase3.1.1.70.474
4du82P0Mevalonate diphosphate decarboxylase/0.474
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.474
1uayADNOxidoreductase/0.473
2a94AP0L-lactate dehydrogenase1.1.1.270.473
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.473
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.473
3qt62P0Mevalonate diphosphate decarboxylase/0.473
4bftZVTPantothenate kinase2.7.1.330.473
4oztP1AEcdysone receptor, putative/0.473
1a59COA2-methylcitrate synthase/0.472
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.472
1mjbACOHistone acetyltransferase ESA1/0.472
1mu8CDBProthrombin3.4.21.50.472
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.472
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.472
2xuoTZ4Acetylcholinesterase3.1.1.70.472
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.472
3fln3FNMitogen-activated protein kinase 14/0.472
3h3qH13Collagen type IV alpha-3-binding protein/0.472
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.472
4blrUTPNTPase P4/0.472
4dfg0JVGag-Pol polyprotein3.4.23.160.472
1rneC60Renin3.4.23.150.471
1u65CP0Acetylcholinesterase3.1.1.70.471
1xvaSAMGlycine N-methyltransferase2.1.1.200.471
2qirCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.471
2xtnGTPGTPase IMAP family member 2/0.471
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.471
4gcmNAPThioredoxin reductase1.8.1.90.471
4u3jGTPTubulin beta chain/0.471
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.471
5dhhDGWNociceptin receptor/0.471
1h73ANPHomoserine kinase2.7.1.390.470
2g1r3IGRenin3.4.23.150.470
2rlcCHDCholoylglycine hydrolase3.5.1.240.470
3r83Z14Cyclin-dependent kinase 22.7.11.220.470
4b1uLABActin, alpha skeletal muscle/0.470
1bwsNDPGDP-L-fucose synthase/0.469
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.469
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3lqfNADGalactitol dehydrogenase/0.469
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.469
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.468
1s3uTQDDihydrofolate reductase1.5.1.30.468
1y7uCOAAcyl-CoA hydrolase/0.468
2a7r5GPGMP reductase 2/0.468
2nniMTKCytochrome P450 2C8/0.468
2xlrFADPutative flavin-containing monooxygenase/0.468
2y60M8FIsopenicillin N synthase1.21.3.10.468
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.468
3nmpPYVAbscisic acid receptor PYL2/0.468
4arbC57Acetylcholinesterase3.1.1.70.468
4mv8ACPBiotin carboxylase6.3.4.140.468
4u0mGTPCyclic GMP-AMP synthase/0.468
4xr9NADCalS8/0.468
2a9y26AAdenosine kinase2.7.1.200.467
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.467
2ffqGSPRas-related protein Rab-6B/0.467
3fr5I4AFatty acid-binding protein, adipocyte/0.467
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.467
3ihzFK5Peptidylprolyl isomerase/0.467
3junAKDPhenazine biosynthesis protein A/B/0.467
3ohh3HHBeta-secretase 13.4.23.460.467
3zoiM2WIsopenicillin N synthase1.21.3.10.467
4araC56Acetylcholinesterase3.1.1.70.467
1bdlIM1Gag-Pol polyprotein3.4.23.160.466
1fwkADPHomoserine kinase2.7.1.390.466
1kvkATPMevalonate kinase2.7.1.360.466
1me6IVSPlasmepsin-23.4.23.390.466
1snfUMPDeoxyuridine 5'-triphosphate nucleotidohydrolase3.6.1.230.466
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.466
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.466
3eksCY9Actin-5C/0.466
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.466
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.466
3phiNDPShikimate dehydrogenase (NADP(+))/0.466
3wagTYDGlycosyltransferase/0.466
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.466
4jlm1NNDeoxycytidine kinase2.7.1.740.466
4uocNCNCinA-like protein/0.466
4xbjIN5Alanine racemase, biosynthetic/0.466
1dz6CAMCamphor 5-monooxygenase1.14.15.10.465
1gj5130Prothrombin3.4.21.50.465
2ab8MTPAdenosine kinase2.7.1.200.465
2dbqNAPGlyoxylate reductase1.1.1.260.465
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.465
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.465
2x06NADL-sulfolactate dehydrogenase/0.465
2zrjAGSProtein RecA/0.465
3evbSAHGenome polyprotein2.1.1.560.465
3p62FMNPentaerythritol tetranitrate reductase/0.465
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.465
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.464
1ddsMTXDihydrofolate reductase1.5.1.30.464
1h22E10Acetylcholinesterase3.1.1.70.464
1ia1NDPDihydrofolate reductase1.5.1.30.464
1vikBAYGag-Pol polyprotein/0.464
2cekN8TAcetylcholinesterase3.1.1.70.464
2g8yNADHydroxycarboxylate dehydrogenase B/0.464
2r8oT5XTransketolase 1/0.464
3a37ADPATPase GET3/0.464
3b2sB2STrichothecene 3-O-acetyltransferase/0.464
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.464
3pi0F91Endothiapepsin3.4.23.220.464
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.464
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.464
4opgFDAConserved Archaeal protein/0.464
4qxaGTPRas-related protein Rab-9A/0.464
4y3jHICEndothiapepsin3.4.23.220.464
4y3rF06Endothiapepsin3.4.23.220.464
4y4jLNREndothiapepsin3.4.23.220.464
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.463
1bk0ACVIsopenicillin N synthase1.21.3.10.463
1kolNADGlutathione-independent formaldehyde dehydrogenase/0.463
1t2cNAIL-lactate dehydrogenase1.1.1.270.463
1w4xFADPhenylacetone monooxygenase1.14.13.920.463
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.463
2fznFADBifunctional protein PutA1.5.5.20.463
2givACOHistone acetyltransferase KAT8/0.463
2iviACWIsopenicillin N synthase1.21.3.10.463
2nr4FMNConserved protein/0.463
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.463
2zsaADPPantothenate kinase2.7.1.330.463
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.463
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.463
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
4dptAGSMevalonate diphosphate decarboxylase/0.463
4hr2ADPNucleoside diphosphate kinase/0.463
4jzr4JREgl nine homolog 1/0.463
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.463
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.463
1ay0TPPTransketolase 12.2.1.10.462
1e66HUXAcetylcholinesterase3.1.1.70.462
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1njfADPDNA polymerase III subunit tau2.7.7.70.462
1npdNADQuinate/shikimate dehydrogenase/0.462
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.462
1uxkNADMalate dehydrogenase/0.462
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.462
2e8hSAHDiphthine synthase/0.462
2fxuBIDActin, alpha skeletal muscle/0.462
2gvdFKPAdenylate cyclase type 2/0.462
2gvdFKPAdenylate cyclase type 5/0.462
2we3DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase/0.462
2wsbNADGalactitol dehydrogenase/0.462
2ym2FADPhenylacetone monooxygenase1.14.13.920.462
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3h3sH15Collagen type IV alpha-3-binding protein/0.462
3hlwCE3Beta-lactamase/0.462
3pe2E1BCasein kinase II subunit alpha2.7.11.10.462
3rsv3RSBeta-secretase 13.4.23.460.462
4lcjNADC-terminal-binding protein 2/0.462
4loh1SYStimulator of interferon genes protein/0.462
4m9aFDAAcyl-CoA dehydrogenase/0.462
1h74ADPHomoserine kinase2.7.1.390.461
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.461
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1z3cSA8mRNA cap guanine-N7 methyltransferase2.1.1.560.461
2ekaSAHDiphthine synthase/0.461
2g1s4IGRenin3.4.23.150.461
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.461
2gjlFMNNitronate monooxygenase1.13.12.160.461
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.461
2q9cGNPSignal recognition particle receptor FtsY/0.461
2stdCRPScytalone dehydratase4.2.1.940.461
2v59LZKBiotin carboxylase6.3.4.140.461
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.461
3ekuCY9Actin-5C/0.461
3nxxNDPDihydrofolate reductase1.5.1.30.461
3r9uFADThioredoxin reductase/0.461
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.461
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.461
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.461
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.460
1gpeFADGlucose oxidase1.1.3.40.460
1gvrTNLPentaerythritol tetranitrate reductase/0.460
1h65GDPTranslocase of chloroplast 343.6.50.460
1ja0NAPNADPH--cytochrome P450 reductase/0.460
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.460
2b7aIZATyrosine-protein kinase JAK2/0.460
2cftPLPPyridoxal phosphate phosphatase/0.460
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.460
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.460
2rqfJH3Hemolymph juvenile hormone binding protein/0.460
2w9hTOPDihydrofolate reductase1.5.1.30.460
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.460
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.460
2y3sTIRTamL/0.460
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
2yvgNADFerredoxin reductase/0.460
2z54AB1Gag-Pol polyprotein3.4.23.160.460
3ai3NDPNADPH-sorbose reductase/0.460
3bhtMFRCyclin-dependent kinase 22.7.11.220.460
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.460
3t7x4SHEndothiapepsin3.4.23.220.460
3zeiAWHO-acetylserine sulfhydrylase/0.460
4d8n0HMKallikrein-63.4.210.460
4gd40WSLysine-specific demethylase 4A1.14.110.460
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.460
4jc51K5Stimulator of interferon genes protein/0.460
4psbGA3Cytokinin-specific binding protein/0.460
4w6z8IDAlcohol dehydrogenase 11.1.1.10.460
5kl9COAAcyl-CoA thioester hydrolase YbgC3.1.20.460
5dhgDGVNociceptin receptor/0.460
1bim0QBRenin3.4.23.150.459
1mvsDTMDihydrofolate reductase1.5.1.30.459
1rdwLARActin, alpha skeletal muscle/0.459
1vbiNADMalate/L-lactate dehydrogenase family protein/0.459
2a2xNA9Prothrombin3.4.21.50.459
2e15SAHDiphthine synthase/0.459
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.459
2ea2F77Methionine aminopeptidase 2/0.459
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.459
2hizLIJBeta-secretase 13.4.23.460.459
2i7pACOPantothenate kinase 32.7.1.330.459
2jb4A14Isopenicillin N synthase1.21.3.10.459
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.459
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.459
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.459
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.459
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.459
3fhxPXLPyridoxal kinase2.7.1.350.459
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.459
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.459
3hy9098A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.459
3zidGDPTubulin-like protein CetZ/0.459
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4hxyNDPPlm1/0.459
4wucANPDNA gyrase subunit B/0.459
1hb1OCVIsopenicillin N synthase1.21.3.10.458
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.458
1r2jFADFkbI/0.458
1ra8FOLDihydrofolate reductase1.5.1.30.458
1rfuADPPyridoxal kinase2.7.1.350.458
1u4oNDDL-lactate dehydrogenase1.1.1.270.458
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.458
2dekSAHDiphthine synthase/0.458
2dxiATPGlutamate--tRNA ligase6.1.1.170.458
2e4nSAHDiphthine synthase/0.458
2huxSAHDiphthine synthase/0.458
2hv9SFGmRNA cap guanine-N7 methyltransferase2.1.1.560.458
2jf0HBPAcetylcholinesterase3.1.1.70.458
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.458
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.458
2rcyNAPPyrroline-5-carboxylate reductase/0.458
3edjBCDCyclomaltodextrinase/0.458
3fp0FP015-O-acetyltransferase/0.458
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3gwdFADCyclohexanone monooxygenase/0.458
3hk1B64Fatty acid-binding protein, adipocyte/0.458
3in6FMNUncharacterized protein/0.458
3pldF90Endothiapepsin3.4.23.220.458
3qvrFADGlucose oxidase1.1.3.40.458
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.458
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.458
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
4nbwNADShort-chain dehydrogenase/reductase SDR/0.458
4z875GPInosine-5'-monophosphate dehydrogenase/0.458
1a9cGTPGTP cyclohydrolase 13.5.4.160.457
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.457
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.457
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
1n77ATPGlutamate--tRNA ligase6.1.1.170.457
1nhkCMPNucleoside diphosphate kinase2.7.4.60.457
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.457
1xz85GPBifunctional protein PyrR2.4.2.90.457
2ahrNAPPyrroline-5-carboxylate reductase/0.457
2dc1NADProbable L-aspartate dehydrogenase/0.457
2drcMTXDihydrofolate reductase1.5.1.30.457
2eh5SAHDiphthine synthase/0.457
2ogyC2F5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase2.1.1.2580.457
2pckSAHDiphthine synthase/0.457
3h2sNDPPutative NADH-flavin reductase/0.457
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.457
3ivgFG5Pantothenate synthetase6.3.2.10.457
3ixp834Ecdysone receptor/0.457
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.457
3lsiFADPyranose 2-oxidase/0.457
3pllF06Endothiapepsin3.4.23.220.457
3rgaILDEpoxide hydrolase LasB5.5.10.457
3toxNAPPutative oxidoreductase/0.457
3w8eNAD3-hydroxybutyrate dehydrogenase/0.457
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.457
4i02CMPcAMP-activated global transcriptional regulator CRP/0.457
4k6fNAPPutative Acetoacetyl-CoA reductase/0.457
4l4xNDPAmphI/0.457
4lol1YEStimulator of interferon genes protein/0.457
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.457
4qxq1YEStimulator of interferon genes protein/0.457
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.457
1k8y13PTryptophan synthase alpha chain/0.456
1psa0ZLPepsin A3.4.23.10.456
1v35NAIEnoyl-ACP reductase/0.456
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2dxvSAHDiphthine synthase/0.456
2emrSAHDiphthine synthase/0.456
2g1o2IGRenin3.4.23.150.456
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
2jji0QSEndothiapepsin3.4.23.220.456
2npxNADNADH peroxidase1.11.1.10.456
2ohvNHLGlutamate racemase/0.456
2zsdCOAPantothenate kinase2.7.1.330.456
3c1kT15Prothrombin3.4.21.50.456
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3f3sNADLambda-crystallin homolog/0.456
3isjA8DPantothenate synthetase6.3.2.10.456
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.456
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.456
3qvpFADGlucose oxidase1.1.3.40.456
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.456
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.456
3tdj3TJGlutamate receptor 2/0.456
3wv9FEGHmd co-occurring protein HcgE/0.456
4ddyDN6Beta-lactamase/0.456
4nxxGDPMitochondrial dynamics protein MID51/0.456
4xd1T3QQdtf/0.456
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.456
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.456
1bmdNADMalate dehydrogenase/0.455
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.455
1dljUGAUDP-glucose 6-dehydrogenase/0.455
1h50FMNPentaerythritol tetranitrate reductase/0.455
1je1GMPPurine nucleoside phosphorylase/0.455
1jpaANPEphrin type-B receptor 22.7.10.10.455
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.455
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.455
1rftPXMPyridoxal kinase2.7.1.350.455
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.455
1tf7ATPCircadian clock protein kinase KaiC2.7.11.10.455
1vjtNADAlpha-glucosidase, putative/0.455
1yhjR6CPyridoxal kinase2.7.1.350.455
2cv2GSUGlutamate--tRNA ligase6.1.1.170.455
2e07SAHDiphthine synthase/0.455
2ewvADPTwitching motility protein PilT/0.455
2fzmFADBifunctional protein PutA1.5.5.20.455
2g82NADGlyceraldehyde-3-phosphate dehydrogenase/0.455
2he5NDPAldo-keto reductase family 1 member C211.1.10.455
2ojg19AMitogen-activated protein kinase 12.7.11.240.455
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.455
2qe2452Polyprotein/0.455
2vwhNAPGlucose 1-dehydrogenase/0.455
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3gfbNADL-threonine 3-dehydrogenase/0.455
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.455
3uylTYDProbable NDP-rhamnosyltransferase/0.455
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.455
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.455
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.455
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.455
4loi1YCStimulator of interferon genes protein/0.455
4zwpM44Xaa-Pro dipeptidase3.4.13.90.455
5c77SAHProtein arginine N-methyltransferase SFM1/0.455
1a72PADAlcohol dehydrogenase E chain1.1.1.10.454
1d6w00RProthrombin3.4.21.50.454
1gvv0GMEndothiapepsin3.4.23.220.454
1hb3SCVIsopenicillin N synthase1.21.3.10.454
1i2lDCSAminodeoxychorismate lyase4.1.3.380.454
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.454
1u9iATPCircadian clock protein kinase KaiC2.7.11.10.454
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.454
1v5z2HCMajor NAD(P)H-flavin oxidoreductase1.6.990.454
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.454
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.454
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2x91LPRAngiotensin-converting enzyme3.4.15.10.454
3amfFMNFMN-binding protein/0.454
3gkaFMNN-ethylmaleimide reductase/0.454
3ipkPMSSurface protein adhesin/0.454
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.454
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4g95OAGDihydrofolate reductase1.5.1.30.454
4hyvPEPPyruvate kinase 12.7.1.400.454
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.454
4opiFDAConserved Archaeal protein/0.454
4tvbNADHomospermidine synthase2.5.1.440.454
4u0mATPCyclic GMP-AMP synthase/0.454
4yj2GTPTubulin alpha-1B chain/0.454
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.454
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.453
1guyNADMalate dehydrogenase/0.453
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.453
1ppkIVVPenicillopepsin-13.4.23.200.453
1ppl1Z7Penicillopepsin-13.4.23.200.453
1rp0AHZThiamine thiazole synthase, chloroplastic/0.453
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.453
1txtCAAHMG-CoA synthase/0.453
1uh5TCLEnoyl-ACP reductase/0.453
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.453
2hr8SAHDiphthine synthase/0.453
2zh6ATPCCA-adding enzyme2.7.7.720.453
3bk2U5PRibonuclease J/0.453
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3h3t16HCollagen type IV alpha-3-binding protein/0.453
3tjzGNPADP-ribosylation factor 1/0.453
3v0tATRPerakine reductase1.1.1.3170.453
3veu0GOBeta-secretase 13.4.23.460.453
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3w77FMNFMN-dependent NADH-azoreductase/0.453
4bzqADPBifunctional enzyme CysN/CysC2.7.1.250.453
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.453
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.453
4hj6FMNLOV protein/0.453
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.453
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.453
4xq9NADHomospermidine synthase2.5.1.440.453
1bwlFMNNADPH dehydrogenase 11.6.99.10.452
1d3dBZTProthrombin3.4.21.50.452
1jdtMTAPurine nucleoside phosphorylase/0.452
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.452
1o5gCR9Prothrombin3.4.21.50.452
1vyrFMNPentaerythritol tetranitrate reductase/0.452
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.452
2dvlFADAcyl-CoA dehydrogenase/0.452
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.452
2pcaSAHDiphthine synthase/0.452
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.452
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.452
2w06FRVCyclin-dependent kinase 22.7.11.220.452
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.452
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3a0tADPSensor histidine kinase/0.452
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.452
3qwpSAMHistone-lysine N-methyltransferase SMYD32.1.1.430.452
3vydVYDRenin3.4.23.150.452
4b63NAPL-ornithine N(5)-monooxygenase/0.452
4cggK5QIntegrase/0.452
4e2dFMNDehydrogenase/0.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4yjdFADD-amino-acid oxidase1.4.3.30.452
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.451
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
1gpuTHDTransketolase 12.2.1.10.451
1jdvADNPurine nucleoside phosphorylase/0.451
1mvtDTMDihydrofolate reductase1.5.1.30.451
1obnASVIsopenicillin N synthase1.21.3.10.451
1vceSAHDiphthine synthase/0.451
2b53D23Cyclin-dependent kinase 22.7.11.220.451
2dftADPShikimate kinase2.7.1.710.451
2e08SAHDiphthine synthase/0.451
2gr1FADFerredoxin reductase/0.451
2owkSAHDiphthine synthase/0.451
2pb6SAHDiphthine synthase/0.451
2w3bNDPDihydrofolate reductase1.5.1.30.451
2wipP49Cyclin-dependent kinase 22.7.11.220.451
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.451
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.451
3keqNADRedox-sensing transcriptional repressor Rex/0.451
3lsmSFDPyranose 2-oxidase/0.451
3mjeNDPAmphB/0.451
3n0hTOPDihydrofolate reductase1.5.1.30.451
3oibFDAPutative acyl-CoA dehydrogenase/0.451
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.451
3rk1ATPN-type ATP pyrophosphatase superfamily/0.451
4b4vL34Bifunctional protein FolD/0.451
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4lz81YXGlutamate receptor 2/0.451
4n6hEJ4Delta-type opioid receptor/0.451
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.451
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
4xfjANPArgininosuccinate synthase/0.451
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.451
4y35F90Endothiapepsin3.4.23.220.451
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
1i59ANPChemotaxis protein CheA2.7.13.30.450
1qjfACSIsopenicillin N synthase1.21.3.10.450
1tkaN3TTransketolase 12.2.1.10.450
2abaSTRPentaerythritol tetranitrate reductase/0.450
2dv7SAHDiphthine synthase/0.450
2fhnBNIAvidin-related protein 4/5/0.450
2jjj0QSEndothiapepsin3.4.23.220.450
2rh9IGPTryptophan synthase alpha chain/0.450
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.450
2zvbSAHPrecorrin-3 C17-methyltransferase/0.450
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.450
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.450
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.450
3sudSUEPolyprotein/0.450
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.450
4c8eC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.450
4de2DN3Beta-lactamase/0.450
4djaFAD(6-4) photolyase/0.450
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.450
4jicFMNGTN Reductase/0.450
4lez1SYCyclic GMP-AMP synthase/0.450
4rrrA3TThreonine--tRNA ligase6.1.1.30.450
4yqfGDPSeptin-9/0.450
1esvLARActin, alpha skeletal muscle/0.449
1g1aNADdTDP-glucose 4,6-dehydratase/0.449
1m76NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
1mewXMPInosine-5'-monophosphate dehydrogenase/0.449
1nfyRTRCoagulation factor X3.4.21.60.449
1nlyAGSCag alpha/0.449
1qtiGNTAcetylcholinesterase3.1.1.70.449
1xl5190Gag-Pol polyprotein3.4.23.160.449
1z7yAA5Cysteine synthase 12.5.1.470.449
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.449
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.449
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2e8qSAHDiphthine synthase/0.449
2egbSAHDiphthine synthase/0.449
2ej2PPEBranched-chain amino acid aminotransferase (IlvE)/0.449
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.449
2gz7D3FOrf1a polyprotein/0.449
2q46NAPUncharacterized protein At5g02240/0.449
3hy7097A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.449
3i0pNADMalate dehydrogenase, putative/0.449
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.449
3k4cFADPyranose 2-oxidase/0.449
3o26NDPSalutaridine reductase/0.449
3qiyQI1Botulinum neurotoxin type A3.4.24.690.449
3t7p7SPEndothiapepsin3.4.23.220.449
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
3vucHHERenin3.4.23.150.449
4a6cQG9Gag-Pol polyprotein3.4.23.160.449
4a862ANMajor pollen allergen Bet v 1-A/0.449
4afgQMRAchbp/0.449
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4b67NAPL-ornithine N(5)-monooxygenase/0.449
4dpy2P0Mevalonate diphosphate decarboxylase/0.449
4egbNADdTDP-glucose 4,6-dehydratase/0.449
4h4tFADBiphenyl dioxygenase ferredoxin reductase subunit/0.449
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.449
4koaNDP1,5-anhydro-D-fructose reductase1.1.1.2920.449
4m6jNDPDihydrofolate reductase1.5.1.30.449
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.449
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.449
4ea30NNNociceptin receptor/0.449
1bxoPP7Penicillopepsin-13.4.23.200.448
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.448
1drhNAPDihydrofolate reductase1.5.1.30.448
1ezvUQ6Cytochrome b/0.448
1h60STRPentaerythritol tetranitrate reductase/0.448
1osvCHCBile acid receptor/0.448
1pwuGM6Lethal factor3.4.24.830.448
1ra3MTXDihydrofolate reductase1.5.1.30.448
1w34FADFerredoxin--NADP reductase1.18.1.20.448
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.448
2bsxNOSPurine nucleoside phosphorylase/0.448
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.448
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2fj1CTCTetracycline repressor protein class D/0.448
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.448
2vwqNAPGlucose 1-dehydrogenase/0.448
2zi224UProthrombin3.4.21.50.448
3a3gDLZLumazine protein/0.448
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3cneFMNPutative protease I/0.448
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.448
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.448
3f1kNAPUncharacterized oxidoreductase YciK10.448
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.448
3imgBZ3Pantothenate synthetase6.3.2.10.448
3iphG11Mitogen-activated protein kinase 14/0.448
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.448
3mpt1GKMitogen-activated protein kinase 14/0.448
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.448
3pftFMNFlavin reductase/0.448
3vdqNAD3-hydroxybutyrate dehydrogenase/0.448
3ziuLSSLeucyl-tRNA synthetase/0.448
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
4hfp15UProthrombin3.4.21.50.448
4i1iNADMalate dehydrogenase/0.448
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.448
4uirFADOleate hydratase4.2.1.530.448
1dhfFOLDihydrofolate reductase1.5.1.30.447
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.447
1gvw0EMEndothiapepsin3.4.23.220.447
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.447
1kh3ANPArgininosuccinate synthase/0.447
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.447
1typFADTrypanothione reductase1.8.1.120.447
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2dsgSAHDiphthine synthase/0.447
2egsSAHDiphthine synthase/0.447
2emuSAHDiphthine synthase/0.447
2futH1SHeparin and heparin-sulfate lyase/0.447
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
2i47KGYDisintegrin and metalloproteinase domain-containing protein 173.4.24.860.447
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2qzlIXSBeta-secretase 13.4.23.460.447
2z4y252Geranylgeranyl pyrophosphate synthase/0.447
2zhf49UProthrombin3.4.21.50.447
3coz54HPantothenate synthetase6.3.2.10.447
3gy0NAPNAD(P)-dependent oxidoreductase/0.447
3hnzPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
3hyoADPPyridoxal kinase/0.447
3iocA5DPantothenate synthetase6.3.2.10.447
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3lstSAHCalO1/0.447
3lzs017Gag-Pol polyprotein3.4.23.160.447
3nwzCOABH2602 protein/0.447
3oafOAGDihydrofolate reductase1.5.1.30.447
3vswR31Renin3.4.23.150.447
4cf1IY7Integrase/0.447
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4i1nFOLDihydrofolate reductase1.5.1.30.447
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.447
4zwmPLPOrnithine aminotransferase, mitochondrial, putative/0.447
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.446
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1meiXMPInosine-5'-monophosphate dehydrogenase/0.446
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.446
1nzdUPGDNA beta-glucosyltransferase/0.446
1orrNADCDP-paratose 2-epimerase/0.446
1pzhNADLactate dehydrogenase/0.446
1rx1NAPDihydrofolate reductase1.5.1.30.446
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.446
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.446
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.446
2dxdANPNucleoside diphosphate kinase2.7.4.60.446
2eglSAHDiphthine synthase/0.446
2ejzSAHDiphthine synthase/0.446
2ha6SCKAcetylcholinesterase3.1.1.70.446
2hfuMEVMevalonate kinase/0.446
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.446
2okcSAMProbable type I restriction enzyme BthVORF4518P M protein2.1.1.720.446
2wzwNDPNitroreductase NfnB/0.446
2xufTZ4Acetylcholinesterase3.1.1.70.446
2znpK55Peroxisome proliferator-activated receptor delta/0.446
2zvcSAHPrecorrin-3 C17-methyltransferase/0.446
3b9lAZZSerum albumin/0.446
3dc3AZMCarbonic anhydrase 24.2.1.10.446
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.446
3fsjD7KBenzoylformate decarboxylase4.1.1.70.446
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.446
3oqkS52Renin3.4.23.150.446
3qfzNOJCellobiose Phosphorylase/0.446
3qlsNDPDihydrofolate reductase1.5.1.30.446
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.446
3v2uATPProtein GAL3/0.446
3vaqADNPutative adenosine kinase/0.446
4bfxZVXPantothenate kinase2.7.1.330.446
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.446
4d89BXDBeta-secretase 13.4.23.460.446
4emtC2EStimulator of interferon genes protein/0.446
4ew3DXZTrifunctional purine biosynthetic protein adenosine-32.1.2.20.446
4f5yC2EStimulator of interferon genes protein/0.446
4fv7E94Mitogen-activated protein kinase 12.7.11.240.446
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.446
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.446
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.446
4xba5GPAprataxin-like protein30.446
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.446
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.446
1cqp803Integrin alpha-L/0.445
1ddrMTXDihydrofolate reductase1.5.1.30.445
1dliUDXUDP-glucose 6-dehydrogenase/0.445
1h63FMNPentaerythritol tetranitrate reductase/0.445
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.445
1rpnNDPGDP-mannose 4,6-dehydratase/0.445
1tqf32PBeta-secretase 13.4.23.460.445
1zgi382Prothrombin3.4.21.50.445
2bjfDXCCholoylglycine hydrolase3.5.1.240.445
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.445
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.445
2el0SAHDiphthine synthase/0.445
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.445
2ozuACOHistone acetyltransferase KAT6A/0.445
2p6lSAHDiphthine synthase/0.445
2qbuSAHPrecorrin-2 methyltransferase/0.445
2rc4ACOHistone acetyltransferase KAT6A/0.445
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.445
2v13C40Renin3.4.23.150.445
2zshGA3Gibberellin receptor GID1A30.445
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3b6zCO7Enoyl reductase LovC10.445
3c35KAIGlutamate receptor ionotropic, kainate 1/0.445
3fvqATPFe(3+) ions import ATP-binding protein FbpC/0.445
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.445
3phjDHKShikimate dehydrogenase (NADP(+))/0.445
3rq8AP5ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.445
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.445
3wgnGSPCell division protein FtsZ/0.445
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
4a7b3W5Collagenase 33.4.240.445
4a86H35Major pollen allergen Bet v 1-A/0.445
4bfzZVZPantothenate kinase2.7.1.330.445
4dfrMTXDihydrofolate reductase1.5.1.30.445
4ge5A89Tyrosine-protein phosphatase non-receptor type 93.1.3.480.445
4lu3AZMCarbonic anhydrase 144.2.1.10.445
4m83ERYOleandomycin glycosyltransferase2.4.10.445
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.445
4qxp1YEStimulator of interferon genes protein/0.445
4xymCOAAcyl-CoA synthetase (NDP forming)/0.445
4y3qF02Endothiapepsin3.4.23.220.445
4yd7F5NEndothiapepsin3.4.23.220.445
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.445
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.445
5stdUNNScytalone dehydratase4.2.1.940.445
1dyiFOLDihydrofolate reductase1.5.1.30.444
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.444
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.444
1gegNADDiacetyl reductase [(S)-acetoin forming]1.1.1.3040.444
1j78VDYVitamin D-binding protein/0.444
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.444
1ky2GNPGTP-binding protein YPT7/0.444
1q84TZ4Acetylcholinesterase3.1.1.70.444
1t2dNADL-lactate dehydrogenase1.1.1.270.444
1u33LM2Pancreatic alpha-amylase/0.444
1wklATPNucleoside diphosphate kinase/0.444
1yqzCOACoenzyme A disulfide reductase/0.444
2c20NADUDP-glucose 4-epimerase/0.444
2dxfGNPNucleoside diphosphate kinase2.7.4.60.444
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.444
2g226IGRenin3.4.23.150.444
2hu2NADC-terminal binding protein 1/0.444
2ikuLIYRenin3.4.23.150.444
2p3b3TLV-1 PROTEASE protein/0.444
2p3b3TLV-1 protease/0.444
2pchSAHDiphthine synthase/0.444
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.444
2v00V15Endothiapepsin3.4.23.220.444
2vkeTACTetracycline repressor protein class D/0.444
2vyqFADFerredoxin--NADP reductase1.18.1.20.444
2xviFADPutative flavin-containing monooxygenase/0.444
2z95NDPGDP-mannose 4,6-dehydratase/0.444
3a9wNADNDP-sugar epimerase/0.444
3ae4FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.444
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.90.444
3f03FMNPentaerythritol tetranitrate reductase/0.444
3tr05GPGuanylate kinase/0.444
3tr9PT1Dihydropteroate synthase/0.444
4chyC5QIntegrase/0.444
4euc0RQSuccinyl-CoA:acetate CoA-transferase/0.444
4frkDWDBeta-secretase 13.4.23.460.444
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.444
5bn3ADPV-type ATP synthase alpha chain/0.444
5bn3ADPNEQ263/0.444
1bcpATPPertussis toxin subunit 4/0.443
1bcpATPPertussis toxin subunit 5/0.443
1dhjMTXDihydrofolate reductase1.5.1.30.443
1dx6GNTAcetylcholinesterase3.1.1.70.443
1i6kTYMTryptophan--tRNA ligase6.1.1.20.443
1nvtNAPShikimate dehydrogenase (NADP(+))/0.443
1qrpHH0Pepsin A-43.4.23.10.443
1toiHCIAspartate aminotransferase2.6.1.10.443
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.443
1z0dGDPRas-related protein Rab-5C/0.443
2an9GDPGuanylate kinase2.7.4.80.443
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.443
2cjfRP43-dehydroquinate dehydratase4.2.1.100.443
2dxwSAHDiphthine synthase/0.443
2eklNADD-3-phosphoglycerate dehydrogenase/0.443
2ivfMGDAlpha-subunit of ethylbenzene dehydrogenase/0.443
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.443
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.443
2p9dSAHDiphthine synthase/0.443
2pb4SAHDiphthine synthase/0.443
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.443
2v7gNADUrocanate hydratase4.2.1.490.443
2zhe13UProthrombin3.4.21.50.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3em3478Gag-Pol polyprotein3.4.23.160.443
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.443
3lpjZ75Beta-secretase 13.4.23.460.443
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3opxU5PSuppressor of disruption of TFIIS/0.443
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.443
3r4b74TGag-Pol polyprotein/0.443
3u78E67Lysine-specific demethylase 7A1.14.110.443
3wrhCAMCamphor 5-monooxygenase1.14.15.10.443
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
4cifJDXIntegrase/0.443
4df2FMNNADPH dehydrogenase/0.443
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.443
4kgkGTPUncharacterized protein/0.443
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
4tx9AMZPhosphoribosyl isomerase A/0.443
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.443
1cbqRE9Cellular retinoic acid-binding protein 2/0.442
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
1e800GQEndothiapepsin3.4.23.220.442
1ebdFADDihydrolipoyl dehydrogenase1.8.1.40.442
1eiiRTLRetinol-binding protein 2/0.442
1f0xFADD-lactate dehydrogenase1.1.1.280.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.442
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.442
1nm6L86Prothrombin3.4.21.50.442
1p0pBCHCholinesterase3.1.1.80.442
1ppm0P1Penicillopepsin-13.4.23.200.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.442
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.442
1wxjIPLTryptophan synthase alpha chain/0.442
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.442
2a5kAZPReplicase polyprotein 1ab3.4.220.442
2dshSAHDiphthine synthase/0.442
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.442
2ji7ADPOxalyl-CoA decarboxylase4.1.1.80.442
2r5nTPPTransketolase 1/0.442
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
3a62STURibosomal protein S6 kinase beta-12.7.11.10.442
3ful52DLeukotriene A-4 hydrolase3.3.2.60.442
3ig6438Urokinase-type plasminogen activator3.4.21.730.442
3juoAJDPhenazine biosynthesis protein A/B/0.442
3juqAKDPhenazine biosynthesis protein A/B/0.442
3k5dXLIBeta-secretase 13.4.23.460.442
3kigDA4Carbonic anhydrase 24.2.1.10.442
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.442
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.442
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.442
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
3rdqDTBStreptavidin/0.442
3s3vTOPDihydrofolate reductase1.5.1.30.442
3s5wFADL-ornithine N(5)-monooxygenase/0.442
3vo8GDPCell division protein FtsZ/0.442
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4dc0NDPPutative ketoacyl reductase1.3.10.442
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.442
4h1vGNPDynamin-1-like protein3.6.5.50.442
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.442
4kbyC2EStimulator of interferon genes protein/0.442
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.442
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.442
7kmeACE_0BN_CHG_PRRProthrombin3.4.21.50.442
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.441
1beuIPLTryptophan synthase alpha chain/0.441
1kfbIGPTryptophan synthase alpha chain/0.441
1lf2R37Plasmepsin-23.4.23.390.441
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.441
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.441
1rsgFADPolyamine oxidase FMS1/0.441
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.441
1tllFMNNitric oxide synthase, brain1.14.13.390.441
1v453DGPurine nucleoside phosphorylase2.4.2.10.441
2briANPUridylate kinase2.7.4.220.441
2ctsCOACitrate synthase, mitochondrial2.3.3.10.441
2dhfDZFDihydrofolate reductase1.5.1.30.441
2e17SAHDiphthine synthase/0.441
2ehlSAHDiphthine synthase/0.441
2ek2SAHDiphthine synthase/0.441
2gblATPCircadian clock protein kinase KaiC2.7.11.10.441
2gtbAZPOrf1ab polyprotein/0.441
2iqgF2IBeta-secretase 13.4.23.460.441
2nm2NEUDihydroneopterin aldolase/0.441
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.441
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.441
2r8pT6FTransketolase 1/0.441
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2w6zL21Biotin carboxylase6.3.4.140.441
2y882ERPhosphoribosyl isomerase A5.3.1.160.441
2zbaZBATrichothecene 3-O-acetyltransferase/0.441
2zfr46UProthrombin3.4.21.50.441
2zxuDSTtRNA dimethylallyltransferase2.5.1.750.441
3arnMSJDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial3.6.1.230.441
3dzvADPHydroxyethylthiazole kinase/0.441
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.441
3lpkZ76Beta-secretase 13.4.23.460.441
3lxiCAMCytochrome P450/0.441
3nd6ATPPhosphopantetheine adenylyltransferase/0.441
3ohf3HFBeta-secretase 13.4.23.460.441
3orfNADDihydropteridine reductase1.5.1.340.441
3pwm017Gag-Pol polyprotein3.4.23.160.441
3qj0QI3Botulinum neurotoxin type A3.4.24.690.441
4b66NAPL-ornithine N(5)-monooxygenase/0.441
4f9gC2EStimulator of interferon genes protein/0.441
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.441
4twnB96Ephrin type-A receptor 32.7.10.10.441
4y3zF41Endothiapepsin3.4.23.220.441
5dp2NAPCurF/0.441
5k7uSAMN6-adenosine-methyltransferase 70 kDa subunit/0.441
1adfTADAlcohol dehydrogenase E chain1.1.1.10.440
1bxqPP8Penicillopepsin-13.4.23.200.440
1cs4FOKAdenylate cyclase type 2/0.440
1cs4FOKAdenylate cyclase type 5/0.440
1e79ATPATP synthase subunit alpha, mitochondrial/0.440
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.440
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.440
1gd1NADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1ib6NADMalate dehydrogenase/0.440
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.440
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.440
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.440
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.440
1omoNADAlanine dehydrogenase/0.440
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.440
2b58COADiamine acetyltransferase 1/0.440
2c12FADNitroalkane oxidase1.7.3.10.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2e8rSAHDiphthine synthase/0.440
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2gevCOKPantothenate kinase2.7.1.330.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2gs7ANPEpidermal growth factor receptor2.7.10.10.440
2huqSAHDiphthine synthase/0.440
2ien017Gag-Pol polyprotein3.4.23.160.440
2jih097A disintegrin and metalloproteinase with thrombospondin motifs 13.4.240.440
2pncCLUPrimary amine oxidase, liver isozyme/0.440
2vhxNADAlanine dehydrogenase1.4.1.10.440
2vqbNAPPutative flavin-containing monooxygenase/0.440
2xuiTZ5Acetylcholinesterase3.1.1.70.440
2zjmF1MBeta-secretase 13.4.23.460.440
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.440
3e23SAMUncharacterized protein/0.440
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.440
3g0dXIHDipeptidyl peptidase 4/0.440
3gbuATPUncharacterized sugar kinase PH14592.7.10.440
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440
3gu83GUDeath-associated protein kinase 12.7.11.10.440
3kry3KRCollagenase 33.4.240.440
3l9hEMQKinesin-like protein KIF11/0.440
3sjhLARActin, alpha skeletal muscle/0.440
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
3w1qYRODihydroorotate dehydrogenase (fumarate)1.3.98.10.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.440
4epq0RRPoly(ADP-ribose) glycohydrolase/0.440
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.440
4ji91M3Tyrosine-protein kinase JAK2/0.440
4n57ADPAPH(2'')-Id/0.440
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.440
4relKMPGlycosyltransferase/0.440
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
4y45F91Endothiapepsin3.4.23.220.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
5il1SAMN6-adenosine-methyltransferase 70 kDa subunit/0.440