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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2oanATPActin, cytoplasmic 1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2oanATPActin, cytoplasmic 1/1.000
1eqyATPActin, alpha skeletal muscle/0.491
1t44ATPActin, alpha skeletal muscle/0.485
3el2ATPActin-5C/0.472
1qz5ATPActin, alpha skeletal muscle/0.468
2q36ATPActin, alpha skeletal muscle/0.467
3eksATPActin-5C/0.467
3mn7ATPActin-5C/0.465
3a5mATPMajor actin/0.463
1s22ATPActin, alpha skeletal muscle/0.462
4cbxATPActin-2/0.459
4k41ATPActin, alpha skeletal muscle/0.450
2p9kATPActin-related protein 2/0.448
4k43ADPActin, alpha skeletal muscle/0.447
1rgiATPActin, alpha skeletal muscle/0.444
1yxqATPActin, alpha skeletal muscle/0.442