sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2oa7	GTX	Glutathione S-transferase P 1	2.5.1.18

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2oa7	GTX	Glutathione S-transferase P 1	2.5.1.18	1.000
1gti	GTB	Glutathione S-transferase P 1	2.5.1.18	0.637
1pgt	GTX	Glutathione S-transferase P	2.5.1.18	0.605
17gs	GTX	Glutathione S-transferase P	2.5.1.18	0.599
12gs	0HH	Glutathione S-transferase P	2.5.1.18	0.595
13gs	SAS	Glutathione S-transferase P	2.5.1.18	0.585
20gs	CBD	Glutathione S-transferase P	2.5.1.18	0.580
1aqx	GTD	Glutathione S-transferase P	2.5.1.18	0.579
3pgt	GBX	Glutathione S-transferase P	2.5.1.18	0.567
2glr	GTX	Glutathione S-transferase P 1	2.5.1.18	0.565
3gus	N11	Glutathione S-transferase P	2.5.1.18	0.561
2oad	GTB	Glutathione S-transferase P 1	2.5.1.18	0.554
2a2s	GSN	Glutathione S-transferase P	2.5.1.18	0.545
2j9h	GTX	Glutathione S-transferase P	2.5.1.18	0.545
3csj	CBL	Glutathione S-transferase P	2.5.1.18	0.531
3ie3	N11	Glutathione S-transferase P	2.5.1.18	0.521
9gss	GTX	Glutathione S-transferase P	2.5.1.18	0.488
1gss	LEE	Glutathione S-transferase P	2.5.1.18	0.487