sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2o4j | VD4 | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2o4j | VD4 | Vitamin D3 receptor | / | 1.000 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.884 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.836 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.750 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.726 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.717 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.708 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.708 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.706 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.700 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.697 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.695 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.695 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.694 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.692 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.692 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.691 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.690 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.690 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.690 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.689 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.689 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.688 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.688 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.687 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.684 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.684 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.683 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.681 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.676 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.675 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.674 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.673 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.673 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.672 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.671 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.670 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.670 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.670 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.667 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.667 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.667 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.667 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.667 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.665 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.665 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.665 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.664 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.662 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.659 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.658 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.657 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.654 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.654 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.654 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.653 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.651 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.650 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.647 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.645 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.644 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.642 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.640 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.638 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.637 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.626 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.622 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.620 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.615 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.521 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.508 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.489 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.489 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.485 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.483 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.482 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.481 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 3bej | MUF | Bile acid receptor | / | 0.476 | |
| 3up0 | D7S | aceDAF-12 | / | 0.476 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.474 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.472 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.472 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.472 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.472 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.470 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.468 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.468 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.467 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.467 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.467 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.466 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.465 | |
| 3zux | TCH | Transporter | / | 0.465 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1eio | GCH | Gastrotropin | / | 0.464 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4iah | 1DX | Alr2278 protein | / | 0.464 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.462 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.462 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.461 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.461 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.460 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.460 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.459 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 3up3 | XCA | aceDAF-12 | / | 0.459 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.459 | |
| 4l9q | 9TP | Serum albumin | / | 0.459 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.458 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.458 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.457 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.457 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.457 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.457 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.454 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1osv | CHC | Bile acid receptor | / | 0.454 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.454 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.454 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.453 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.453 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.452 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.451 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3wd7 | COA | Acridone synthase | / | 0.451 | |
| 4l9k | EHF | Serum albumin | / | 0.451 | |
| 4okt | 198 | Androgen receptor | / | 0.451 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.450 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.450 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.450 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.450 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.449 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.449 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.448 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.448 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.448 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.448 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1sn5 | T3 | Transthyretin | / | 0.447 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.447 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.447 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.447 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.446 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.446 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.445 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.445 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.445 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.445 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.443 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.442 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.442 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.442 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.441 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.441 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.440 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.440 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.440 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.440 |