sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2o2r | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2o2r | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 1.000 | |
| 4go2 | TAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.643 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.617 | |
| 2o2q | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.614 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.577 | |
| 4nmj | NAP | Aldehyde dehydrogenase | / | 0.563 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.554 | |
| 1qi1 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.553 | |
| 3n83 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.552 | |
| 4h73 | NDP | Aldehyde dehydrogenase | / | 0.552 | |
| 4oe2 | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.552 | |
| 4zuk | NAD | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.541 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.538 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.537 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.537 | |
| 4fr8 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.530 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.530 | |
| 1bpw | NAD | Betaine aldehyde dehydrogenase | 1.2.1.8 | 0.529 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.529 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.526 | |
| 2y5d | NAP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.524 | |
| 2onm | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.522 | |
| 3rhd | NAP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.522 | |
| 2j6l | NAI | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.520 | |
| 2wme | NAP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.520 | |
| 4itb | NDP | Succinate-semialdehyde dehydrogenase | / | 0.520 | |
| 1nzz | NAI | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.518 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.518 | |
| 3v9l | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.516 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.514 | |
| 2d4e | NAD | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] | / | 0.512 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.511 | |
| 4nmk | NAP | Aldehyde dehydrogenase | / | 0.510 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.501 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.500 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.497 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.496 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.496 | |
| 1nzw | NAI | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.495 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.495 | |
| 4wb9 | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.495 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.494 | |
| 4zz7 | NAD | Methylmalonate-semialdehyde dehydrogenase | / | 0.494 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.492 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.491 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.486 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.485 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.482 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.481 | |
| 1ad3 | NAD | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.480 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.480 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.479 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.479 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.478 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.477 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.476 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.476 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.475 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.474 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.474 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.474 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.474 | |
| 1o00 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.473 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.473 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.472 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.471 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.471 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.469 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.469 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.469 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.469 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.469 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.468 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.468 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.468 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.468 | |
| 1osv | CHC | Bile acid receptor | / | 0.467 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.467 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.467 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.467 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.467 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.466 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.466 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.466 | |
| 4hdr | DMD | ArsB | / | 0.466 | |
| 4l9q | 9TP | Serum albumin | / | 0.466 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.465 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.464 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.464 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.464 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.463 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.463 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.462 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.462 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.462 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.462 | |
| 3qce | NXY | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.462 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.462 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.461 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.461 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.461 | |
| 2qe0 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.461 | |
| 2yat | EEU | Estrogen receptor | / | 0.461 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.461 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.461 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.460 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.460 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.460 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.460 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.460 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.459 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.459 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.458 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.458 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.458 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3v49 | PK0 | Androgen receptor | / | 0.457 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.457 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.456 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.456 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.456 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.456 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.456 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.456 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1l0l | FMX | Cytochrome b | / | 0.455 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.455 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.455 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.455 | |
| 4i1w | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.455 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.454 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.453 | |
| 1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.453 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.453 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.453 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.453 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.453 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.453 | |
| 1h48 | CDI | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.452 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.452 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3a7d | FBN | Catechol O-methyltransferase | 2.1.1.6 | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.451 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.451 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.451 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.450 | |
| 2eg5 | SAH | 7-methylxanthosine synthase 1 | / | 0.450 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.450 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.450 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 2p15 | EZT | Estrogen receptor | / | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.449 | |
| 4okx | 198 | Androgen receptor | / | 0.449 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.448 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.448 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.448 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.448 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.448 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.447 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.447 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.447 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.447 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.447 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.447 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.447 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.447 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.447 | |
| 4inb | 1F6 | Gag protein | / | 0.447 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 1e3r | AND | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.446 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.446 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.446 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.446 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.446 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.446 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.445 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.445 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3u8m | 09R | Acetylcholine-binding protein | / | 0.445 | |
| 3zok | NAD | 3-dehydroquinate synthase, chloroplastic | 4.2.3.4 | 0.445 | |
| 4aoa | IK2 | Beta-phenylalanine transaminase | 2.6.1 | 0.445 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.445 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.445 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.445 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.444 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3am4 | FT1 | Enoyl-ACP reductase | / | 0.444 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.444 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.444 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.444 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.444 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.444 | |
| 4ku3 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.444 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.443 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.443 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.443 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 3stx | BKA | Methylketone synthase I | / | 0.443 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.443 | |
| 3zzh | NLG | Protein ARG5,6, mitochondrial | 2.7.2.8 | 0.443 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.443 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.443 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.442 | |
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1yre | COA | Uncharacterized protein | / | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.442 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.442 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.441 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.441 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.441 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 3fro | NHF | GlgA glycogen synthase | / | 0.441 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.441 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.440 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.440 | |
| 2fav | APR | Nonstructural polyprotein pp1a | / | 0.440 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.440 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.440 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.440 |