sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2o2m | LI0 | Bcl-2-like protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2o2m | LI0 | Bcl-2-like protein 1 | / | 1.000 | |
| 3qkd | HI0 | Bcl-2-like protein 1 | / | 0.508 | |
| 3inq | X0J | Bcl-2-like protein 1 | / | 0.487 | |
| 3wiz | LC6 | Bcl-2-like protein 1 | / | 0.487 | |
| 3h23 | B54 | Dihydropteroate synthase | / | 0.481 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.466 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.464 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.463 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.461 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.455 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.455 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.454 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.453 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.453 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.453 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.452 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 4p5f | AR6 | Inosine-uridine nucleoside N-ribohydrolase | / | 0.445 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.445 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.444 | |
| 3rup | ADP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 3ewr | APR | Replicase polyprotein 1a | 3.4.22 | 0.441 |