sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jf9 | OHT | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2jf9 | OHT | Estrogen receptor | / | 1.000 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.521 | |
| 1uom | PTI | Estrogen receptor | / | 0.518 | |
| 1yin | CM3 | Estrogen receptor | / | 0.514 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.513 | |
| 2pog | WST | Estrogen receptor | / | 0.511 | |
| 1err | RAL | Estrogen receptor | / | 0.495 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.490 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.466 | |
| 2jfa | RAL | Estrogen receptor | / | 0.456 | |
| 1nde | MON | Estrogen receptor beta | / | 0.455 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.450 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.450 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.443 |