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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.619
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.610
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.582
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.568
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.564
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.560
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.559
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.550
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.512
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.448
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441