Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.74

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.741.000
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.643
2vnaNAPProstaglandin reductase 21.3.1.480.530
2y05NAPProstaglandin reductase 1/0.499
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.497
2zb3NDPProstaglandin reductase 21.3.1.480.454