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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2izkGLLStreptavidin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2izkGLLStreptavidin/1.000
2rtkGLLStreptavidin/0.855
2rtmIMIStreptavidin/0.741
2izjBTNStreptavidin/0.713
2rtnIMIStreptavidin/0.705
3ry2BTNStreptavidin/0.691
2rtoIMIStreptavidin/0.689
2rtfBTNStreptavidin/0.668
2iziBTNStreptavidin/0.667
4bx7B4FStreptavidin/0.658
2rtiGLLStreptavidin/0.657
2izhBTNStreptavidin/0.650
1luqBTNStreptavidin/0.643
1mk5BTNStreptavidin/0.643
2y3fBTNStreptavidin/0.639
4dneDTBStreptavidin/0.638
1df8BTNStreptavidin/0.637
1lcwSHMStreptavidin/0.636
1srfMTBStreptavidin/0.635
4gdaBTNStreptavidin/0.634
2aviBTNAvidin/0.631
2rteBTNStreptavidin/0.630
2izfBTNStreptavidin/0.623
1rxhBNIStreptavidin/0.622
1stpBTNStreptavidin/0.621
3wyqBTNStreptavidin/0.621
2rtpIMIStreptavidin/0.618
2fhnBNIAvidin-related protein 4/5/0.616
2rtqIMIStreptavidin/0.616
1lczBH7Streptavidin/0.614
1sreHABStreptavidin/0.614
1srhMOBStreptavidin/0.614
2izlIMIStreptavidin/0.614
2rtdBTNStreptavidin/0.614
2rtrIMIStreptavidin/0.613
2rtgBTNStreptavidin/0.612
2izgBTNStreptavidin/0.611
1sriDMBStreptavidin/0.610
1avdBTNAvidin/0.601
1srgMHBStreptavidin/0.596
3t2wBTNAvidin/streptavidin/0.596
1i9hBNIStreptavidin/0.594
2c4iBTNAvidin/0.585
2rtlIMIStreptavidin/0.581
1srjNABStreptavidin/0.578
1swtBTNStreptavidin/0.575
3wznBTNStreptavidin/0.575
3rdqDTBStreptavidin/0.570
2fhlBNIAvidin-related protein 4/5/0.562
4z28BTNHoefavidin/0.556
4bcsBTNAvidin-related protein 4/5/0.553
3ew2BTNHypothetical conserved protein/0.545
3wypBSOStreptavidin/0.542
1nc9IMIStreptavidin/0.541
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.541
1y52BTNAvidin-related protein 4/5/0.537
1swpBTNStreptavidin/0.528
1swpBTQStreptavidin/0.527
2uywBTNAvd protein/0.527
2uz2BTNAvd protein/0.526
2zscBTNTamavidin2/0.526
1n9mBTNStreptavidin/0.524
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.522
3nr4PYVAbscisic acid receptor PYL2/0.516
1swnBTNStreptavidin/0.513
1rx1NAPDihydrofolate reductase1.5.1.30.512
1swdBTNStreptavidin/0.509
1ndjBTNStreptavidin/0.506
2a5c8DAAvidin/0.503
2vbdV10Isopenicillin N synthase1.21.3.10.503
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.498
1mrqSTRAldo-keto reductase family 1 member C1/0.496
1n0uSO1Elongation factor 2/0.496
2jb4A14Isopenicillin N synthase1.21.3.10.496
1hb1OCVIsopenicillin N synthase1.21.3.10.494
2vcmM11Isopenicillin N synthase1.21.3.10.494
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.494
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.494
3nj0PYVAbscisic acid receptor PYL2/0.494
5iqdGNPBifunctional AAC/APH2.3.10.494
2zjwREFCasein kinase II subunit alpha2.7.11.10.493
4twnB96Ephrin type-A receptor 32.7.10.10.493
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.492
1obnASVIsopenicillin N synthase1.21.3.10.492
3vf60H6Glucokinase2.7.1.20.492
4je5PLPAromatic/aminoadipate aminotransferase 12.6.1.390.492
2x6o2TCTetracycline repressor protein class D/0.491
1pd9CO4Dihydrofolate reductase1.5.1.30.490
5h8tRTLRetinol-binding protein 1/0.490
2wo7ASVIsopenicillin N synthase1.21.3.10.489
1bk0ACVIsopenicillin N synthase1.21.3.10.488
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.488
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.488
3pqbVGPPutative oxidoreductase/0.488
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.488
4g8bHL6Alpha/beta hydrolase fold protein/0.488
4ja1NGHStromelysin-13.4.24.170.488
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.488
3qakUKAAdenosine receptor A2a/0.488
1dfoPLGSerine hydroxymethyltransferase2.1.2.10.487
1nw6SFGModification methylase RsrI2.1.1.720.487
3fhxPLPPyridoxal kinase2.7.1.350.487
4bb3KKAIsopenicillin N synthase1.21.3.10.487
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.487
3d84NDPDihydrofolate reductase1.5.1.30.486
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.486
2y60M8FIsopenicillin N synthase1.21.3.10.485
3d7zGK5Mitogen-activated protein kinase 14/0.485
3t8vBTJM1 family aminopeptidase3.4.110.485
3zkyWT4Isopenicillin N synthase1.21.3.10.485
4ggzBTNBll1558 protein/0.485
4m6l21VDihydrofolate reductase1.5.1.30.485
2iviACWIsopenicillin N synthase1.21.3.10.484
3bi6396Wee1-like protein kinase2.7.10.20.484
1lb9DNQGlutamate receptor 2/0.483
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.483
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.483
4eqrCOACoenzyme A disulfide reductase/0.483
4gbeSAHDNA adenine methylase2.1.1.720.483
4prxADPDNA gyrase subunit B/0.483
1rftPXMPyridoxal kinase2.7.1.350.482
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.482
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.482
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
3rdoBTNStreptavidin/0.482
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
4ffrATPUncharacterized protein/0.482
1vf2GTXGlutathione S-transferase 32.5.1.180.481
2tohHBITyrosine 3-monooxygenase1.14.16.20.481
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.481
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.481
4fhd0TTSpore photoproduct lyase/0.481
4psbGA3Cytokinin-specific binding protein/0.481
4rtkSAHDNA adenine methylase2.1.1.720.481
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.481
4yvbBTNStreptavidin/0.481
1fvpFMANon-fluorescent flavoprotein/0.480
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.480
1tj1FADBifunctional protein PutA1.5.5.20.480
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.480
2npfMOUElongation factor 2/0.480
2xtbKRMAdenosine kinase, putative/0.480
3c14FOKAdenylate cyclase type 2/0.480
3c14FOKAdenylate cyclase type 5/0.480
3up0D7SaceDAF-12/0.480
4tjy3GNTankyrase-22.4.2.300.480
4x5gFOLDihydrofolate reductase1.5.1.30.480
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
1wur8DGGTP cyclohydrolase 1/0.479
1xddAAYIntegrin alpha-L/0.479
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.479
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.479
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.479
4a83DXCMajor pollen allergen Bet v 1-A/0.479
4cukNAID-lactate dehydrogenase/0.479
5eccNAPDehydrofolate reductase type I/0.479
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.479
2fznFADBifunctional protein PutA1.5.5.20.478
3nga3NGCasein kinase II subunit alpha2.7.11.10.478
4xq9NADHomospermidine synthase2.5.1.440.478
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.477
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.477
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.477
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
3rl45GPMetallophosphoesterase MPPED23.10.477
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.477
1d3pBT3Prothrombin3.4.21.50.476
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.476
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.476
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.476
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.476
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.476
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.476
4eqwCOACoenzyme A disulfide reductase/0.476
4jlj1NMDeoxycytidine kinase2.7.1.740.476
4oztP1AEcdysone receptor, putative/0.476
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.475
1mvtDTMDihydrofolate reductase1.5.1.30.475
1z6tADPApoptotic protease-activating factor 1/0.475
3h3r14HCollagen type IV alpha-3-binding protein/0.475
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.475
5iqbGNPBifunctional AAC/APH2.3.10.475
1kt6RTLRetinol-binding protein 4/0.474
1zq5E04Aldo-keto reductase family 1 member C3/0.474
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
2w3mFOLDihydrofolate reductase1.5.1.30.474
3atzFMNProstaglandin F2a synthase/0.474
3dd0EZLCarbonic anhydrase 24.2.1.10.474
3oikWZBCarbonic anhydrase 24.2.1.10.474
4a2aATPCell division protein FtsA/0.474
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.474
1dr5NAPDihydrofolate reductase1.5.1.30.473
1x2hLPALipoate-protein ligase A6.3.1.200.473
2op18PCEnoyl-ACP reductase/0.473
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.473
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.473
3h3qH13Collagen type IV alpha-3-binding protein/0.473
4bj8BTNAvidin/0.473
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.473
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.473
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.473
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.473
1ie9VDXVitamin D3 receptor/0.472
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.472
1qiqACCIsopenicillin N synthase1.21.3.10.472
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.472
3c1oNAPEugenol synthase/0.472
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
3gxfIFMGlucosylceramidase3.2.1.450.472
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
4j7xSASSepiapterin reductase1.1.1.1530.472
1s3vTQDDihydrofolate reductase1.5.1.30.471
1x8lOXRRetinol dehydratase/0.471
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.471
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.471
3arvSAUChitinase A/0.471
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.471
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.471
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.471
4kwhNAPReductase homolog/0.471
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.470
1qknRALEstrogen receptor beta/0.470
1qrpHH0Pepsin A-43.4.23.10.470
2j9lATPH(+)/Cl(-) exchange transporter 5/0.470
2w6oOA3Biotin carboxylase6.3.4.140.470
2zevIPEGeranylgeranyl pyrophosphate synthase/0.470
3pe2E1BCasein kinase II subunit alpha2.7.11.10.470
3rimTPPTransketolase2.2.1.10.470
3tq8TOPDihydrofolate reductase/0.470
3zoiM2WIsopenicillin N synthase1.21.3.10.470
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.470
4c6zTLE3-oxoacyl-ACP synthase/0.470
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.470
4dpy2P0Mevalonate diphosphate decarboxylase/0.470
4g95OAGDihydrofolate reductase1.5.1.30.470
4iaq2GM5-hydroxytryptamine receptor 1B/0.470
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.470
3emlZMAAdenosine receptor A2a/0.470
1eg2MTAModification methylase RsrI2.1.1.720.469
1kziTHGThymidylate synthase/0.469
1lkeDOGBilin-binding protein/0.469
1qjfACSIsopenicillin N synthase1.21.3.10.469
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.469
1x8b824Wee1-like protein kinase2.7.10.20.469
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
2gjlFMNNitronate monooxygenase1.13.12.160.469
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.469
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.469
3ntz3TZDihydrofolate reductase1.5.1.30.469
3sp9IL2Peroxisome proliferator-activated receptor delta/0.469
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.469
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.469
4fhbFOLDihydrofolate reductase1.5.1.30.469
4xqcNADHomospermidine synthase2.5.1.440.469
1h51FMNPentaerythritol tetranitrate reductase/0.468
1klkPMDDihydrofolate reductase1.5.1.30.468
2g8yNADHydroxycarboxylate dehydrogenase B/0.468
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.468
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.468
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.468
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.468
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.468
3fhxPXLPyridoxal kinase2.7.1.350.468
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.468
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.468
3up3XCAaceDAF-12/0.468
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4aosFADSteroid monooxygenase/0.468
4jlk1NODeoxycytidine kinase2.7.1.740.468
4r1lADPPhenylacetate-coenzyme A ligase/0.468
4relKMPGlycosyltransferase/0.468
1b3dS27Stromelysin-13.4.24.170.467
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.467
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.467
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.467
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.467
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.467
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.467
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.467
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.467
4ejmNAPPutative zinc-binding dehydrogenase/0.467
4jtrIZPAldo-keto reductase family 1 member C2/0.467
4ly91YYGlucokinase regulatory protein/0.467
4orkGDPBifunctional AAC/APH2.3.10.467
4pnmNU1Tankyrase-22.4.2.300.467
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.467
1hb3SCVIsopenicillin N synthase1.21.3.10.466
1jpaANPEphrin type-B receptor 22.7.10.10.466
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
2fszOHTEstrogen receptor beta/0.466
2vbpVB1Isopenicillin N synthase1.21.3.10.466
2xlpFADPutative flavin-containing monooxygenase/0.466
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.466
1dliUDXUDP-glucose 6-dehydrogenase/0.465
1dr3TAPDihydrofolate reductase1.5.1.30.465
1p0pBCHCholinesterase3.1.1.80.465
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.465
2rqfJH3Hemolymph juvenile hormone binding protein/0.465
2w6mOA1Biotin carboxylase6.3.4.140.465
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.465
3e2sFADBifunctional protein PutA1.5.5.20.465
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
5cb3APRO-acetyl-ADP-ribose deacetylase/0.465
1dlsMTXDihydrofolate reductase1.5.1.30.464
1drhNAPDihydrofolate reductase1.5.1.30.464
1fkxPRHAdenosine deaminase3.5.4.40.464
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.464
1ly4COQDihydrofolate reductase1.5.1.30.464
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.464
1o6qR17Squalene--hopene cyclase4.2.1.1290.464
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.464
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.464
2hl2SSAThreonine--tRNA ligase6.1.1.30.464
2rhrEMOPutative ketoacyl reductase1.3.10.464
2vprTDCTetracycline repressor protein class H/0.464
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2xvhFADPutative flavin-containing monooxygenase/0.464
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.464
3v2uATPProtein GAL3/0.464
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.464
4dc0NDPPutative ketoacyl reductase1.3.10.464
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
5dp2NAPCurF/0.464
1f4gTP4Thymidylate synthase/0.463
1h36R88Squalene--hopene cyclase4.2.1.1290.463
1rkhVD2Vitamin D3 receptor/0.463
1ta6177Prothrombin3.4.21.50.463
1vj3TABDihydrofolate reductase1.5.1.30.463
2bf7HBIPteridine reductase 11.5.1.330.463
2bu9HFVIsopenicillin N synthase1.21.3.10.463
2fzhDH1Dihydrofolate reductase1.5.1.30.463
2pitDHTAndrogen receptor/0.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.463
3biu10UProthrombin3.4.21.50.463
3c1kT15Prothrombin3.4.21.50.463
3c3xNAPEugenol synthase 11.1.1.3180.463
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.463
3gncQQQGlutaryl-CoA dehydrogenase/0.463
3iexGMPPurine nucleoside phosphorylase/0.463
4a862ANMajor pollen allergen Bet v 1-A/0.463
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.463
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.463
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.463
4l1xSTRAldo-keto reductase family 1 member C2/0.463
4pb25UDNucleoside permease/0.463
1gj5130Prothrombin3.4.21.50.462
1uy9PU6Heat shock protein HSP 90-alpha/0.462
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2flhZEACytokinin-specific binding protein/0.462
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.462
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.462
2x0rNADMalate dehydrogenase/0.462
2z3uCRRCytochrome P450/0.462
3biy01KHistone acetyltransferase p300/0.462
3csdEMOPutative ketoacyl reductase1.3.10.462
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.462
3owuEQUSteroid Delta-isomerase5.3.3.10.462
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4g8cC6LAlpha/beta hydrolase fold protein/0.462
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.462
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.462
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.462
4j6bPLOCytochrome P450 monooxygenase/0.462
4wzyATPMaltokinase2.7.1.1750.462
4xrgNADHomospermidine synthase2.5.1.440.462
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.461
1yhjR6CPyridoxal kinase2.7.1.350.461
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.461
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
2dhfDZFDihydrofolate reductase1.5.1.30.461
2ea4F79Methionine aminopeptidase 2/0.461
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.461
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.461
2oegUPGUDP-glucose pyrophosphorylase/0.461
2pivDHTAndrogen receptor/0.461
2tscCB3Thymidylate synthase/0.461
2xlsFADPutative flavin-containing monooxygenase/0.461
4b66NAPL-ornithine N(5)-monooxygenase/0.461
4j6cSTRCytochrome P450 monooxygenase/0.461
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.461
4uyg73BBromodomain-containing protein 2/0.461
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.461
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.461
4ug2NGIAdenosine receptor A2a/0.461
1jtqLY3Thymidylate synthase/0.460
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2fonFADAcyl-coenzyme A oxidase/0.460
2fziDH3Dihydrofolate reductase1.5.1.30.460
2jgsBTNAvidin/0.460
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.460
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.460
3djfBC3Purine nucleoside phosphorylase/0.460
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3fp0FP015-O-acetyltransferase/0.460
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
3havATPAminoglycoside phosphotransferase/0.460
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.460
3s41S41Glucokinase2.7.1.20.460
3zeiAWHO-acetylserine sulfhydrylase/0.460
4qzuRTLRetinol-binding protein 2/0.460
1rxjBNIStreptavidin/0.459
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.459
1tojHCIAspartate aminotransferase2.6.1.10.459
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.459
1zgbA1EAcetylcholinesterase3.1.1.70.459
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.459
2ea1GPGRibonuclease I3.1.27.60.459
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.459
2fzjDH3Dihydrofolate reductase1.5.1.30.459
2w6zL21Biotin carboxylase6.3.4.140.459
3bejMUFBile acid receptor/0.459
3h3sH15Collagen type IV alpha-3-binding protein/0.459
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3nguADPNucleoside diphosphate kinase/0.459
3nl6TPSUncharacterized protein/0.459
3qly55VUncharacterized protein/0.459
3vhhVHHAvidin/0.459
3zv5BPYCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.459
4a84DXCMajor pollen allergen Bet v 1-A/0.459
4dbzNDPPutative ketoacyl reductase1.3.10.459
4fflADPUncharacterized protein/0.459
4g2fC07Ephrin type-A receptor 32.7.10.10.459
4jlm1NNDeoxycytidine kinase2.7.1.740.459
4l64C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase2.1.1.140.459
4mr61K0Bromodomain-containing protein 2/0.459
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.459
4nb6444Nuclear receptor ROR-gamma/0.459
4ocvANPAminoglycoside phosphotransferase/0.459
4q71FADBifunctional protein PutA/0.459
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.459
4rtmSAMDNA adenine methylase2.1.1.720.459
4ure1PSCyclohexanol dehydrogenase/0.459
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.459
5fkkTDCTetracycline repressor protein class D/0.459
5iua6DXAdenosine receptor A2a/0.459
1me6IVSPlasmepsin-23.4.23.390.458
1uyhPU0Heat shock protein HSP 90-alpha/0.458
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.458
1z7yAA5Cysteine synthase 12.5.1.470.458
1zgv501Prothrombin3.4.21.50.458
2cdaNAPGlucose 1-dehydrogenase/0.458
2g1pSAHDNA adenine methylase2.1.1.720.458
2r2mI50Prothrombin3.4.21.50.458
3a783EVVitamin D3 receptor/0.458
3bx5304Mitogen-activated protein kinase 14/0.458
3h3t16HCollagen type IV alpha-3-binding protein/0.458
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3lfzADPUncharacterized protein MJ1225/0.458
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.458
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.458
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.458
4c73TLH3-oxoacyl-ACP synthase/0.458
4iarERM5-hydroxytryptamine receptor 1B/0.458
4k6fNAPPutative Acetoacetyl-CoA reductase/0.458
4mhtSAHModification methylase HhaI2.1.1.370.458
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.458
5gcnCOAHAT A1/0.458
1culFOKAdenylate cyclase type 2/0.457
1culFOKAdenylate cyclase type 5/0.457
1dkfBMSRetinoic acid receptor alpha/0.457
1ie8KH1Vitamin D3 receptor/0.457
1mvsDTMDihydrofolate reductase1.5.1.30.457
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.457
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
2w3bNDPDihydrofolate reductase1.5.1.30.457
3c3eGDP2-phospho-L-lactate transferase/0.457
3cseN22Uncharacterized protein/0.457
3n0yAPCAdenylate cyclase 2/0.457
4b1rITCTetracycline repressor protein class D/0.457
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.457
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.457
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4jhiEMUNodulin-13/0.457
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.457
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.457
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.457
9mhtSAHModification methylase HhaI2.1.1.370.457
3sn6P0GBeta-2 adrenergic receptor/0.457
1d3dBZTProthrombin3.4.21.50.456
1dr3HBIDihydrofolate reductase1.5.1.30.456
1errRALEstrogen receptor/0.456
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
1lf3EH5Plasmepsin-23.4.23.390.456
1nzq162Prothrombin3.4.21.50.456
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.456
1s7gNADNAD-dependent protein deacylase 2/0.456
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.456
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.456
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.456
2hb8MVDVitamin D3 receptor/0.456
2j2pSC2Ficolin-2/0.456
2od7A1RNAD-dependent protein deacetylase HST23.5.10.456
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.456
3b05IPEIsopentenyl-diphosphate delta-isomerase/0.456
3kudGDPGTPase HRas/0.456
3ns2PYVAbscisic acid receptor PYL2/0.456
3qls55VDihydrofolate reductase1.5.1.30.456
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.456
3zkuHCVIsopenicillin N synthase1.21.3.10.456
4c02TAKActivin receptor type-12.7.11.300.456
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.456
4g2h0VQVitamin D3 receptor A/0.456
4gukP2GNeuronal calcium sensor 1/0.456
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.456
4k9oTPPBenzoylformate decarboxylase4.1.1.70.456
4prvADPDNA gyrase subunit B/0.456
4uofDATNucleoside diphosphate kinase/0.456
4zwpM44Xaa-Pro dipeptidase3.4.13.90.456
5fuwTHMThymidine kinase, putative/0.456
5iqaGNPBifunctional AAC/APH2.3.10.456
5iqiGNPBifunctional AAC/APH2.3.10.456
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.455
1d9i00PProthrombin3.4.21.50.455
1eveE20Acetylcholinesterase3.1.1.70.455
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.455
1m78NDPDihydrofolate reductase1.5.1.30.455
1p8dCO1Oxysterols receptor LXR-beta/0.455
1qsnCOAHAT A1/0.455
1tj2FADBifunctional protein PutA1.5.5.20.455
2pksG44Prothrombin3.4.21.50.455
2po7CHDFerrochelatase, mitochondrial4.99.1.10.455
2wi72KLHeat shock protein HSP 90-alpha/0.455
2yk2YJWHeat shock protein HSP 90-alpha/0.455
2zhe13UProthrombin3.4.21.50.455
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3eksCY9Actin-5C/0.455
3g7jGTXGlutathione transferase GST1-4/0.455
3gtsD3MDdmC/0.455
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3r96ACOMccE protein/0.455
3zv7NHGAcetylcholinesterase3.1.1.70.455
4g2i0VQVitamin D3 receptor/0.455
4i9i1DYTankyrase-12.4.2.300.455
4jq3ZOMAldo-keto reductase family 1 member C2/0.455
4mv1ADPBiotin carboxylase6.3.4.140.455
4nbwNADShort-chain dehydrogenase/reductase SDR/0.455
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.455
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.455
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.455
4ys22BAUncharacterized protein/0.455
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.455
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.455
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.454
1dghNDPCatalase1.11.1.60.454
1ix1BB2Peptide deformylase/0.454
1ndzFR5Adenosine deaminase3.5.4.40.454
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.454
1xf0ASDAldo-keto reductase family 1 member C3/0.454
2bakAQZMitogen-activated protein kinase 14/0.454
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.454
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2v3wTPPBenzoylformate decarboxylase4.1.1.70.454
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.454
3p62FMNPentaerythritol tetranitrate reductase/0.454
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.454
3w0aDS5Vitamin D3 receptor/0.454
3w5rLOAVitamin D3 receptor/0.454
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
3znqSS8D-amino-acid oxidase1.4.3.30.454
4a9yAQZMitogen-activated protein kinase 14/0.454
4ap3FADSteroid monooxygenase/0.454
4du6GTPGTP cyclohydrolase 1/0.454
4du82P0Mevalonate diphosphate decarboxylase/0.454
4dz7D02Carbonic anhydrase 24.2.1.10.454
4pd6URINucleoside permease/0.454
4xo7ASDAldo-keto reductase family 1 member C2/0.454
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.454
5k2cZMAAdenosine receptor A2a/0.454
1blzACVIsopenicillin N synthase1.21.3.10.453
1cd2FOLDihydrofolate reductase1.5.1.30.453
1eioGCHGastrotropin/0.453
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1nbuPH2Dihydroneopterin aldolase/0.453
1o6rR19Squalene--hopene cyclase4.2.1.1290.453
1xp8AGSProtein RecA/0.453
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1zgaHMKIsoflavone 4'-O-methyltransferase/0.453
2gvdFKPAdenylate cyclase type 2/0.453
2gvdFKPAdenylate cyclase type 5/0.453
2hcdBIVVitamin D3 receptor A/0.453
2ofv242Tyrosine-protein kinase Lck2.7.10.20.453
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.453
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.453
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.453
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.453
3r0tFU9Casein kinase II subunit alpha2.7.11.10.453
3sgy06WDihydrofolate reductase1.5.1.30.453
3v76FDAUncharacterized protein/0.453
3vt5YI2Vitamin D3 receptor/0.453
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.453
4a86H35Major pollen allergen Bet v 1-A/0.453
4a8v2ANMajor pollen allergen Bet v 1-J/0.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.453
4dpeNGHStromelysin-13.4.24.170.453
4hfp15UProthrombin3.4.21.50.453
4hmhF94Tankyrase-22.4.2.300.453
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.453
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.453
4isuIKMGlutamate receptor 2/0.453
4l5b1UXDeoxycytidine kinase2.7.1.740.453
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.453
4rtsSAMDNA adenine methylase2.1.1.720.453
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.453
4xd1T3QQdtf/0.453
5c1mCLRMu-type opioid receptor/0.453
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.453
1hfqMOTDihydrofolate reductase1.5.1.30.452
1jwtBLIProthrombin3.4.21.50.452
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.452
1n5dNDPCarbonyl reductase [NADPH] 1/0.452
1opbRETRetinol-binding protein 2/0.452
1t7o152Carnitine O-acetyltransferase2.3.1.70.452
1u0hFOKAdenylate cyclase type 2/0.452
1u0hFOKAdenylate cyclase type 5/0.452
2c27ACOMycothiol acetyltransferase2.3.1.1890.452
2jblSMAReaction center protein L chain/0.452
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.452
2qg2A91Heat shock protein HSP 90-alpha/0.452
2qw8NAPEugenol synthase 11.1.1.3180.452
2v59LZKBiotin carboxylase6.3.4.140.452
2ykiYKIHeat shock protein HSP 90-alpha/0.452
2zseACPPantothenate kinase2.7.1.330.452
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.452
3gl2D3MDdmC/0.452
3hl0NADMaleylacetate reductase/0.452
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3n0hTOPDihydrofolate reductase1.5.1.30.452
3p8jFMNPentaerythritol tetranitrate reductase/0.452
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.452
3tq9MTXDihydrofolate reductase/0.452
3uudESTEstrogen receptor/0.452
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.452
4dz5NAPAldo-keto reductase family 1 member C3/0.452
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4eiyZMAAdenosine receptor A2a/0.452
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.452
4rtqSAHDNA adenine methylase2.1.1.720.452
4yao2AMNADPH--cytochrome P450 reductase/0.452
4zasTYDCalS13/0.452
5irnADPNucleotide binding oligomerization domain containing 2/0.452
1kvkATPMevalonate kinase2.7.1.360.451
1ngsTPPTransketolase 12.2.1.10.451
1qs2NADVip2Ac/0.451
1ra2FOLDihydrofolate reductase1.5.1.30.451
1s36CEIObelin/0.451
1szcCNANAD-dependent protein deacetylase HST23.5.10.451
1uxvNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.451
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.451
2c29NAPDihydroflavonol 4-reductase/0.451
2g1r3IGRenin3.4.23.150.451
2jfaRALEstrogen receptor/0.451
2nnqT4BFatty acid-binding protein, adipocyte/0.451
2ociTYCValacyclovir hydrolase3.10.451
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.451
2qocANPEphrin type-A receptor 32.7.10.10.451
2qx7NAPEugenol synthase 11.1.1.3180.451
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
2x7hPFNProstaglandin reductase 310.451
2xlrFADPutative flavin-containing monooxygenase/0.451
2yeiXQIHeat shock protein HSP 90-alpha/0.451
2z2w770Wee1-like protein kinase2.7.10.20.451
2zi53L1Deoxycytidine kinase2.7.1.740.451
2zs8ADPPantothenate kinase2.7.1.330.451
3e8xNAPBH1520 protein/0.451
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3sr5Q12Dihydrofolate reductase1.5.1.30.451
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.451
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.451
4at0FADPossible succinate dehydrogenase/0.451
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.451
4g1y0VOVitamin D3 receptor A/0.451
4g1z0VPVitamin D3 receptor A/0.451
4ha6PXMPyridoxine 4-oxidase/0.451
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.451
4y3qF02Endothiapepsin3.4.23.220.451
1a4lDCFAdenosine deaminase3.5.4.40.450
1cdeGARPhosphoribosylglycinamide formyltransferase/0.450
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.450
1fmjRTLRetinol dehydratase/0.450
1hk5T44Serum albumin/0.450
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1p4mADPRiboflavin kinase2.7.1.260.450
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.450
1t87CAMCamphor 5-monooxygenase1.14.15.10.450
2amaDHTAndrogen receptor/0.450
2ao6R18Androgen receptor/0.450
2he5NDPAldo-keto reductase family 1 member C211.1.10.450
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.450
2piwDHTAndrogen receptor/0.450
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.450
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
2y67N21UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
2zfr46UProthrombin3.4.21.50.450
3af1GDPPantothenate kinase2.7.1.330.450
3anlSYC1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.450
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3i6qNDPPutative leucoanthocyanidin reductase 1/0.450
3n6uTSUHTH-type transcriptional regulator TsaR/0.450
3nmpPYVAbscisic acid receptor PYL2/0.450
3owj1ELCasein kinase II subunit alpha2.7.11.10.450
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.450
3pd4A3GThreonine--tRNA ligase6.1.1.30.450
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.450
3qzyFADFAD-linked sulfhydryl oxidase/0.450
3rupADPBiotin carboxylase6.3.4.140.450
3saxE50Carbonic anhydrase 24.2.1.10.450
3vt3VDXVitamin D3 receptor/0.450
4a81DXCMajor pollen allergen Bet v 1-A/0.450
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.450
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4dliIRGMitogen-activated protein kinase 14/0.450
4dvi2IWTankyrase-12.4.2.300.450
4eftEFTHeat shock protein HSP 90-alpha/0.450
4eji0QACytochrome P450 2A131.14.14.10.450
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.450
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.450
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.450
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.450
4imfSI3N-acetylneuraminate lyase/0.450
4ixc1JDGlucokinase2.7.1.20.450
4jzr4JREgl nine homolog 1/0.450
4kne1CYDihydrofolate reductase1.5.1.30.450
4q0kGA3Phytohormone-binding protein/0.450
4y4jLNREndothiapepsin3.4.23.220.450
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.449
1ao8MTXDihydrofolate reductase1.5.1.30.449
1ay0TPPTransketolase 12.2.1.10.449
1dnaCB3Thymidylate synthase/0.449
1fecFADTrypanothione reductase1.8.1.120.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1hvyD16Thymidylate synthase2.1.1.450.449
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1m2qMNXCasein kinase II subunit alpha2.7.11.10.449
1o2g696Prothrombin3.4.21.50.449
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.449
1yimCM4Estrogen receptor/0.449
2bfmTOPPteridine reductase 11.5.1.330.449
2h55DZ8Heat shock protein HSP 90-alpha/0.449
2in6839Wee1-like protein kinase2.7.10.20.449
2j3qTFLAcetylcholinesterase3.1.1.70.449
2uxhQUEHTH-type transcriptional regulator TtgR/0.449
2wu2CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.449
2wu2CBESuccinate dehydrogenase cytochrome b556 subunit/0.449
3fywXCFDihydrofolate reductase1.5.1.30.449
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.449
3hz5Z64Heat shock protein HSP 90-alpha/0.449
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3kpzZNEVitamin D3 receptor/0.449
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.449
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3w0c6DSVitamin D3 receptor/0.449
3w0iO11Vitamin D3 receptor/0.449
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.449
4lrrCF9Thymidylate synthase/0.449
4nh82LCHeat shock protein HSP 90-alpha/0.449
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.449
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.449
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.448
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
1ezfIN0Squalene synthase2.5.1.210.448
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.448
1ia1NDPDihydrofolate reductase1.5.1.30.448
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1o5rFR9Adenosine deaminase3.5.4.40.448
1oc1ASVIsopenicillin N synthase1.21.3.10.448
1ppl1Z7Penicillopepsin-13.4.23.200.448
1psa0ZLPepsin A3.4.23.10.448
1s19MC9Vitamin D3 receptor/0.448
1s3uTQDDihydrofolate reductase1.5.1.30.448
1svmATPLarge T antigen3.6.40.448
1uxjNADMalate dehydrogenase/0.448
1w6rGNTAcetylcholinesterase3.1.1.70.448
1yzqGNPRas-related protein Rab-6A/0.448
2amb17HAndrogen receptor/0.448
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.448
2hvdADPNucleoside diphosphate kinase A2.7.4.60.448
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.448
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.448
2qpyDHTAndrogen receptor/0.448
2vmyFFOSerine hydroxymethyltransferase/0.448
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.448
2yk2YJXHeat shock protein HSP 90-alpha/0.448
3biz61EWee1-like protein kinase2.7.10.20.448
3cr0809Wee1-like protein kinase2.7.10.20.448
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
3mb714ICasein kinase II subunit alpha2.7.11.10.448
3t3iGPWGlycogen phosphorylase, muscle form2.4.1.10.448
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.448
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4fkxCDPNucleoside diphosphate kinase/0.448
4ivw1GJEstrogen receptor/0.448
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.448
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.448
5jtbZMAAdenosine receptor A2a/0.448
1aoeGW3Dihydrofolate reductase1.5.1.30.447
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.447
1c4uIH1Prothrombin3.4.21.50.447
1dhiMTXDihydrofolate reductase1.5.1.30.447
1diuBDMDihydrofolate reductase1.5.1.30.447
1drbMTXDihydrofolate reductase1.5.1.30.447
1f5fDHTSex hormone-binding globulin/0.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
1jdzFMBPurine nucleoside phosphorylase/0.447
1thnADPAnti-sigma F factor/0.447
1tl1H18Gag-Pol polyprotein2.7.7.490.447
1ws1BB2Peptide deformylase 1/0.447
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.447
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.447
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.447
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
2hk9NAPShikimate dehydrogenase (NADP(+))/0.447
2hl1A3SThreonine--tRNA ligase6.1.1.30.447
2hveADPNucleoside diphosphate kinase A2.7.4.60.447
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.447
2vqbFADPutative flavin-containing monooxygenase/0.447
2x8gFADThioredoxin glutathione reductase/0.447
2z4sADPChromosomal replication initiator protein DnaA/0.447
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.447
3c36KAIGlutamate receptor ionotropic, kainate 1/0.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3nuvASDSteroid Delta-isomerase5.3.3.10.447
3phiNDPShikimate dehydrogenase (NADP(+))/0.447
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.447
3qm4PN0Cytochrome P450 2D6/0.447
3qwc98PProthrombin3.4.21.50.447
3srsM23Dihydrofolate reductase1.5.1.30.447
3vrwYS5Vitamin D3 receptor/0.447
3vtdTKDVitamin D3 receptor/0.447
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.447
4bfxZVXPantothenate kinase2.7.1.330.447
4bw39BMBromodomain-containing protein 4/0.447
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4gevCB3Thymidylate synthase/0.447
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.447
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4kl9NDPDihydrofolate reductase1.5.1.30.447
4pl9ADPEthylene receptor 1/0.447
4qedNAPElxO/0.447
4xivADPChemotaxis protein CheA2.7.13.30.447
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.447
5fdg0N8Polymerase acidic protein/0.447
5k2bZMAAdenosine receptor A2a/0.447
1cbrREACellular retinoic acid-binding protein 1/0.446
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.446
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.446
1t76DHTAndrogen receptor/0.446
1tilATPAnti-sigma F factor/0.446
1v93FADMethylenetetrahydrofolate reductase/0.446
2a5kAZPReplicase polyprotein 1ab3.4.220.446
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.446
2e0nSAHPrecorrin-2 C20-methyltransferase/0.446
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.446
2io6330Wee1-like protein kinase2.7.10.20.446
2jddACOProbable acetyltransferase/0.446
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.446
2qo9ANPEphrin type-A receptor 32.7.10.10.446
2v13C40Renin3.4.23.150.446
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.446
2zc922UProthrombin3.4.21.50.446
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3njoPYVAbscisic acid receptor PYR1/0.446
3ql3FOLDihydrofolate reductase1.5.1.30.446
3sigAR6Uncharacterized protein/0.446
3ukoNADAlcohol dehydrogenase class-3/0.446
3w0hW12Vitamin D3 receptor/0.446
4bfsZVSPantothenate kinase2.7.1.330.446
4elf35IDihydrofolate reductase/0.446
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.446
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4gqkADPActin cross-linking toxin VgrG1/0.446
4jq7KJQEpidermal growth factor receptor2.7.10.10.446
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4nr82LLBromodomain-containing protein 4/0.446
4o71CPBBromodomain-containing protein 4/0.446
4o95245Cytokinin dehydrogenase 4/0.446
4x5hFOLDihydrofolate reductase1.5.1.30.446
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.446
5a3bAPRSIR2 family protein/0.446
5bylGCPBifunctional AAC/APH2.3.10.446
5kf9COAPredicted acetyltransferase/0.446
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.445
1cjkFOKAdenylate cyclase type 2/0.445
1cjkFOKAdenylate cyclase type 5/0.445
1dr2TAPDihydrofolate reductase1.5.1.30.445
1e3gR18Androgen receptor/0.445
1fmlRTLRetinol dehydratase/0.445
1ftlDNQGlutamate receptor 2/0.445
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.445
1odnAPVIsopenicillin N synthase1.21.3.10.445
1phhFADp-hydroxybenzoate hydroxylase/0.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
1t4u81AProthrombin3.4.21.50.445
1txiTX5Vitamin D3 receptor/0.445
1upw444Oxysterols receptor LXR-beta/0.445
1uydPU8Heat shock protein HSP 90-alpha/0.445
1v35NAIEnoyl-ACP reductase/0.445
1ygkRRCPyridoxal kinase2.7.1.350.445
1yw8A75Methionine aminopeptidase 2/0.445
2bfpH4BPteridine reductase 11.5.1.330.445
2ejzSAHDiphthine synthase/0.445
2hamC33Vitamin D3 receptor/0.445
2hq9FADMll6688 protein/0.445
2uuk897Prothrombin3.4.21.50.445
2w3wVG9Dihydrofolate reductase/0.445
2w71L23Biotin carboxylase6.3.4.140.445
2wmdZZ0NmrA-like family domain-containing protein 1/0.445
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.445
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.445
3fql79ZGenome polyprotein2.7.7.480.445
3gyf51PDihydrofolate reductase1.5.1.30.445
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.445
3ojiPYVAbscisic acid receptor PYL3/0.445
3q43D66M1 family aminopeptidase3.4.110.445
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3vrvYSDVitamin D3 receptor/0.445
3w8wFADPutative FAD-dependent oxygenase EncM/0.445
4bqyFNTEgl nine homolog 1/0.445
4c77N01Phenylacetone monooxygenase1.14.13.920.445
4dieC5PCytidylate kinase/0.445
4dptAGSMevalonate diphosphate decarboxylase/0.445
4e37NDPCatalase1.11.1.60.445
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4iteTEYVitamin D3 receptor/0.445
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.445
4l8u9AZSerum albumin/0.445
4m9aFDAAcyl-CoA dehydrogenase/0.445
4ofrDHTAndrogen receptor/0.445
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.445
4uohADPNucleoside diphosphate kinase/0.445
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.445
5im3DTPRibonucleoside-diphosphate reductase/0.445
5iu4ZMAAdenosine receptor A2a/0.445
1bim0QBRenin3.4.23.150.444
1d4pBPPProthrombin3.4.21.50.444
1dx6GNTAcetylcholinesterase3.1.1.70.444
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.444
1kt3RTLRetinol-binding protein 4/0.444
1nw5SAMModification methylase RsrI2.1.1.720.444
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.444
1pq6965Oxysterols receptor LXR-beta/0.444
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.444
1sq5ADPPantothenate kinase2.7.1.330.444
1szgFNSCytochrome b2, mitochondrial1.1.2.30.444
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1toiHCIAspartate aminotransferase2.6.1.10.444
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
1xm1GAHProthrombin3.4.21.50.444
1yc2NADNAD-dependent protein deacylase 2/0.444
1yslCOAHydroxymethylglutaryl-CoA synthase2.3.3.100.444
2bbqPFGThymidylate synthase/0.444
2bjsACVIsopenicillin N synthase1.21.3.10.444
2bxmIMNSerum albumin/0.444
2c7qSAHModification methylase HhaI2.1.1.370.444
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.444
2ea2F77Methionine aminopeptidase 2/0.444
2gjnFMNNitronate monooxygenase1.13.12.160.444
2gvcFADThiol-specific monooxygenase1.14.130.444
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
2ii3CAOLipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.444
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.444
2nm2NEUDihydroneopterin aldolase/0.444
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3e39FMNNitroreductase/0.444
3fl9TOPDihydrofolate reductase/0.444
3fyvXCFDihydrofolate reductase1.5.1.30.444
3hl7I46Mitogen-activated protein kinase 14/0.444
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.444
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
3jqcJU2Pteridine reductase, putative/0.444
3klbFMNUncharacterized protein/0.444
3nxxNDPDihydrofolate reductase1.5.1.30.444
3q5pTACMultidrug-efflux transporter 1 regulator/0.444
3r5yF42Uncharacterized protein/0.444
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3wqmB29Diterpene synthase3.1.7.80.444
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.444
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.444
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.444
4h9753SDihydrofolate reductase1.5.1.30.444
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.444
4jauADPSensor histidine kinase/0.444
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.444
4mr51K0Bromodomain-containing protein 2/0.444
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.444
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.444
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.444
4rtoSFGDNA adenine methylase2.1.1.720.444
4wecNADShort chain dehydrogenase/0.444
4y0kNAPAntE/0.444
4z24FADPutative GMC-type oxidoreductase R13510.444
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.444
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.444
7catNDPCatalase1.11.1.60.444
5g53NECAdenosine receptor A2a/0.444
1a9cGTPGTP cyclohydrolase 13.5.4.160.443
1b2lNDCAlcohol dehydrogenase1.1.1.10.443
1dhfFOLDihydrofolate reductase1.5.1.30.443
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.443
1ludTRRDihydrofolate reductase1.5.1.30.443
1svlADPLarge T antigen3.6.40.443
1tl7FOKAdenylate cyclase type 2/0.443
1tl7FOKAdenylate cyclase type 5/0.443
1x1rGDPRas-related protein M-Ras/0.443
1x7b041Estrogen receptor beta/0.443
1xq3R18Androgen receptor/0.443
1yluFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
1zd9GDPADP-ribosylation factor-like protein 8A/0.443
2a9y26AAdenosine kinase2.7.1.200.443
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.443
2b1z17MEstrogen receptor/0.443
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.443
2cekN8TAcetylcholinesterase3.1.1.70.443
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2ftoTMPThymidylate synthase/0.443
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.443
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.443
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2v58LZJBiotin carboxylase6.3.4.140.443
2vdvSAMtRNA (guanine-N(7)-)-methyltransferase/0.443
2vkdUPGCytotoxin L/0.443
2w9hTOPDihydrofolate reductase1.5.1.30.443
2ydoADNAdenosine receptor A2a/0.443
2yhuWHFPteridine reductase/0.443
3cluFADElectron transfer flavoprotein subunit alpha/0.443
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3eblGA4Gibberellin receptor GID1/0.443
3ehjACPSensor histidine kinase DesK2.7.13.30.443
3friSAH16S rRNA methylase/0.443
3ggcH26Hypoxanthine-guanine phosphoribosyltransferase2.4.2.80.443
3gy9COAGCN5-related N-acetyltransferase/0.443
3koo24DBifunctional epoxide hydrolase 23.3.2.100.443
3nx2FERFerulic acid decarboxylase/0.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.443
3tm5SFGUncharacterized protein/0.443
4bquCLRJapanin/0.443
4dhyS41Glucokinase2.7.1.20.443
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443
4n3l2FNProthrombin3.4.21.50.443
4okx198Androgen receptor/0.443
4rrfA3SThreonine--tRNA ligase6.1.1.30.443
4v2gITCTetracycline repressor protein class D/0.443
4y9lFADAcyl-CoA dehydrogenase family member 11/0.443
5k2aZMAAdenosine receptor A2a/0.443
1c1c612Gag-Pol polyprotein2.7.7.490.442
1c7oPPGHemolysin/0.442
1cqp803Integrin alpha-L/0.442
1dyrTOPDihydrofolate reductase1.5.1.30.442
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1fw0KAIGlutamate receptor 2/0.442
1gwrESTEstrogen receptor/0.442
1h35R01Squalene--hopene cyclase4.2.1.1290.442
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.442
1kt7RTLRetinol-binding protein 4/0.442
1mdrAPGMandelate racemase/0.442
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
1pq944BOxysterols receptor LXR-beta/0.442
1r8qAFBCytohesin-2/0.442
1r8qAFBADP-ribosylation factor 1/0.442
1sdmADPKinesin heavy chain-like protein/0.442
1tkbN1TTransketolase 12.2.1.10.442
1trgCB3Thymidylate synthase/0.442
1u3dFADCryptochrome-1/0.442
1uyePU9Heat shock protein HSP 90-alpha/0.442
1wsvTHHAminomethyltransferase, mitochondrial/0.442
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.442
2fai459Estrogen receptor/0.442
2j5xGSPADP-ribosylation factor 6/0.442
2qe5617Polyprotein/0.442
2rlcCHDCholoylglycine hydrolase3.5.1.240.442
2wotZZGTGF-beta receptor type-12.7.11.300.442
2x9dITCTetracycline repressor protein class D/0.442
2zhw12UProthrombin3.4.21.50.442
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.442
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
3elySAHMethyltransferase/0.442
3iw4LW4Protein kinase C alpha type2.7.11.130.442
3k4551PDihydrofolate reductase1.5.1.30.442
3k8q22APurine nucleoside phosphorylase2.4.2.10.442
3ollESTEstrogen receptor beta/0.442
3p84FMNPentaerythritol tetranitrate reductase/0.442
3qgf46FGenome polyprotein2.7.7.480.442
3vi7CBDHematopoietic prostaglandin D synthase/0.442
4b67NAPL-ornithine N(5)-monooxygenase/0.442
4bfwZVWPantothenate kinase2.7.1.330.442
4cmfPXGUncharacterized protein/0.442
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.442
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4g1d0VKVitamin D3 receptor A/0.442
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.442
4h6rFDAProline dehydrogenase/0.442
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.442
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.442
4iqqD16Thymidylate synthase/0.442
4l0qNADAlcohol dehydrogenase class-3/0.442
4l4xNDPAmphI/0.442
4lyw21QBromodomain-containing protein 4/0.442
4n6hEJ4Delta-type opioid receptor/0.442
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.442
4qxmNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4rtpSAMDNA adenine methylase2.1.1.720.442
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.442
5cmx0G6Prothrombin3.4.21.50.442
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.442
5uviZMAAdenosine receptor A2a/0.442
1bwlFMNNADPH dehydrogenase 11.6.99.10.441
1crbRTLRetinol-binding protein 1/0.441
1disBDMDihydrofolate reductase1.5.1.30.441
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.441
1h65GDPTranslocase of chloroplast 343.6.50.441
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.441
1ktsC24Prothrombin3.4.21.50.441
1l8qADPChromosomal replication initiator protein DnaA/0.441
1oriSAHProtein arginine N-methyltransferase 1/0.441
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.441
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.441
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.441
1t7rDHTAndrogen receptor/0.441
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1wxyFRKAdenosine deaminase3.5.4.40.441
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.441
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.441
2a9z26AAdenosine kinase2.7.1.200.441
2abbFMNPentaerythritol tetranitrate reductase/0.441
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.441
2bvs2CEProthrombin3.4.21.50.441
2d32ANPGlutamate--cysteine ligase6.3.2.20.441
2gpuOHTEstrogen-related receptor gamma/0.441
2j14GNIPeroxisome proliferator-activated receptor delta/0.441
2jdcCAOProbable acetyltransferase/0.441
2jh6894Prothrombin3.4.21.50.441
2r6jNDPEugenol synthase 11.1.1.3180.441
2r8oT5XTransketolase 1/0.441
2rhtC1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.441
2xw7NDPDihydrofolate reductase/0.441
2ylpTESAndrogen receptor/0.441
2ze2T27Gag-Pol polyprotein2.7.7.490.441
2zynBCDPeriplasmic binding protein/0.441
3a1l2CCCytochrome P450/0.441
3bk2U5PRibonuclease J/0.441
3fazNOSPurine nucleoside phosphorylase/0.441
3fo7IMNPhospholipase A2 VRV-PL-VIIIa/0.441
3gb4D3MDdmC/0.441
3gvhNADMalate dehydrogenase/0.441
3hk1B64Fatty acid-binding protein, adipocyte/0.441
3ldfSAHUncharacterized protein/0.441
3och2MXDihydrofolate reductase1.5.1.30.441
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3owaFADAcyl-CoA dehydrogenase/0.441
3p1799PProthrombin3.4.21.50.441
3pg3DG7Mitogen-activated protein kinase 14/0.441
3qlrQLRDihydrofolate reductase1.5.1.30.441
3s7a684Dihydrofolate reductase1.5.1.30.441
3sqyQ11Dihydrofolate reductase1.5.1.30.441
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.441
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.441
4a87NARMajor pollen allergen Bet v 1-A/0.441
4afgQMRAchbp/0.441
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4ele31IDihydrofolate reductase/0.441
4f6w0SSCyclin-dependent kinase 82.7.11.220.441
4fgh0U6Dihydrofolate reductase1.5.1.30.441
4fhf0TTSpore photoproduct lyase/0.441
4ixgIXGDihydrofolate reductase1.5.1.30.441
4j26ESTEstrogen receptor beta/0.441
4k5o1OTM1 family aminopeptidase3.4.110.441
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.441
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.441
4xr9TMPCalS8/0.441
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
1d5cGDPGTPase (Rab6)/0.440
1dgbNDPCatalase1.11.1.60.440
1e2nRCAThymidine kinase/0.440
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1kekHTLPyruvate synthase/0.440
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.440
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.440
1r58AO5Methionine aminopeptidase 2/0.440
1t74DHTAndrogen receptor/0.440
1uy6PU3Heat shock protein HSP 90-alpha/0.440
1uymPU3Heat shock protein HSP 90-beta/0.440
1zdfUPGGlycogenin-12.4.1.1860.440
1zdwFLVPrenyltransferase/0.440
1zgi382Prothrombin3.4.21.50.440
2aj4ANPGalactokinase2.7.1.60.440
2cftPLPPyridoxal phosphate phosphatase/0.440
2h94FADLysine-specific histone demethylase 1A10.440
2hb7O1CVitamin D3 receptor/0.440
2hl0A3SThreonine--tRNA ligase6.1.1.30.440
2ij7TPFMycocyclosin synthase1.14.21.90.440
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.440
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2w6qOA5Biotin carboxylase6.3.4.140.440
2xuiTZ5Acetylcholinesterase3.1.1.70.440
2yee2ECHeat shock protein HSP 90-alpha/0.440
2ylwNAPPhenylacetone monooxygenase1.14.13.920.440
2zshGA3Gibberellin receptor GID1A30.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3b6zCO7Enoyl reductase LovC10.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.440
3ddw055Glycogen phosphorylase, liver form2.4.1.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3i2834NBifunctional epoxide hydrolase 23.3.2.100.440
3junAKDPhenazine biosynthesis protein A/B/0.440
3jynNDPQuinone oxidoreductase/0.440
3l0lHC3Nuclear receptor ROR-gamma/0.440
3lqfNADGalactitol dehydrogenase/0.440
3n19FNRXenobiotic reductase/0.440
3owyEQUSteroid Delta-isomerase5.3.3.10.440
3p9tTCLRepressor/0.440
3pejBC2Endoplasmin homolog, putative/0.440
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.440
3qgi33FGenome polyprotein2.7.7.480.440
3qiyQI1Botulinum neurotoxin type A3.4.24.690.440
3sfy3FYUncharacterized protein/0.440
3tm4SAMUncharacterized protein/0.440
3w78CBDFMN-dependent NADH-azoreductase/0.440
4askK0ILysine-specific demethylase 6B1.14.110.440
4er7AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.440
4fxy0W2Neurolysin, mitochondrial3.4.24.160.440
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.440
4g8zTOPDihydrofolate reductase1.5.1.30.440
4h6pFMNChromate reductase/0.440
4j7uYTZSepiapterin reductase1.1.1.1530.440
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
4ug7H4BNitric oxide synthase oxygenase1.14.13.1650.440
4x5fFOLDihydrofolate reductase1.5.1.30.440
5a9sNAPPutative dehydrogenase/0.440
5aqzSGVHeat shock 70 kDa protein 1A/0.440
5efwFMNNPH1-1/0.440
4mqt2CUMuscarinic acetylcholine receptor M2/0.440