sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2ipi	AKY	Aclacinomycin-N/aclacinomycin-A oxidase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2ipi	AKY	Aclacinomycin-N/aclacinomycin-A oxidase	/	1.000
3uzw	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.451
1w6r	GNT	Acetylcholinesterase	3.1.1.7	0.449
2ejz	SAH	Diphthine synthase	/	0.448
3g1r	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.448
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.443
1fap	RAP	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.441
1fap	RAP	Serine/threonine-protein kinase mTOR	2.7.11.1	0.441
4a95	9MT	Glycylpeptide N-tetradecanoyltransferase	/	0.441
4hcy	0YN	Transketolase	/	0.441
1t7o	152	Carnitine O-acetyltransferase	2.3.1.7	0.440
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.440