sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 1.000 | |
| 2iiq | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.547 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.487 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.467 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.465 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.455 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.455 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.454 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.448 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.445 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.444 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 3a3g | DLZ | Lumazine protein | / | 0.441 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.441 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.440 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 |