sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ibu | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2ibu | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 1.000 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.730 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.612 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.506 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.465 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.449 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.446 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.445 | |
| 4l4x | NDP | AmphI | / | 0.445 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 |