sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2i9k	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2i9k	SAH	Modification methylase HhaI	2.1.1.37	1.000
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.653
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.643
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.627
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.618
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.611
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.603
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.601
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.589
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.584
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.580
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.564
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.539
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.526
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.517