sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 1.000 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.547 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.524 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.523 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.514 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.513 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.512 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.508 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.507 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.507 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.506 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.506 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.503 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.502 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.501 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.496 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.494 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.489 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.489 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.488 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.488 | |
| 2e8h | SAH | Diphthine synthase | / | 0.488 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.488 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.488 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.487 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.486 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.486 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.486 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.484 | |
| 6req | 3CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.484 | |
| 2oke | DUP | DUTP pyrophosphatase | / | 0.483 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.482 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.482 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.482 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.480 | |
| 2p6l | SAH | Diphthine synthase | / | 0.480 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.480 | |
| 4fd2 | ADP | Chaperone protein ClpB | / | 0.480 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.480 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 4die | C5P | Cytidylate kinase | / | 0.479 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.478 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.478 | |
| 4uoc | NCN | CinA-like protein | / | 0.478 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.477 | |
| 2e16 | SAH | Diphthine synthase | / | 0.476 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.476 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4jic | FMN | GTN Reductase | / | 0.476 | |
| 2e4n | SAH | Diphthine synthase | / | 0.475 | |
| 2owg | SAH | Diphthine synthase | / | 0.475 | |
| 4e2b | FMN | Dehydrogenase | / | 0.475 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.474 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2egl | SAH | Diphthine synthase | / | 0.474 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.474 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.474 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.474 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.473 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.473 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.473 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.472 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.472 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.472 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.472 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.472 | |
| 3b9l | AZZ | Serum albumin | / | 0.472 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.472 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.472 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.471 | |
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.471 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.471 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.471 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.470 | |
| 2hux | SAH | Diphthine synthase | / | 0.470 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.470 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.470 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.470 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.470 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.469 | |
| 2huv | SAH | Diphthine synthase | / | 0.469 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.469 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2hut | SAH | Diphthine synthase | / | 0.468 | |
| 2owu | SAH | Diphthine synthase | / | 0.468 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4e2d | FMN | Dehydrogenase | / | 0.468 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.468 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.467 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.467 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.467 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.467 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.467 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.467 | |
| 1fdi | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.466 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.466 | |
| 1yun | ATP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.466 | |
| 2e8r | SAH | Diphthine synthase | / | 0.466 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 2p6i | SAH | Diphthine synthase | / | 0.466 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.466 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.466 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.466 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.466 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.466 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.466 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.466 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 1fdo | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.465 | |
| 2ejj | SAH | Diphthine synthase | / | 0.465 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.465 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.465 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 4x3m | ADN | RNA 2'-O ribose methyltransferase | / | 0.465 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.464 | |
| 2e15 | SAH | Diphthine synthase | / | 0.464 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.464 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.464 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 2owv | SAH | Diphthine synthase | / | 0.464 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.464 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.464 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.464 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 1wng | SAH | Diphthine synthase | / | 0.463 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.463 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.463 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.463 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.462 | |
| 2dek | SAH | Diphthine synthase | / | 0.462 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.462 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.462 | |
| 2pca | SAH | Diphthine synthase | / | 0.462 | |
| 2pch | SAH | Diphthine synthase | / | 0.462 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.462 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.462 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.462 | |
| 5fm6 | ADP | RuvB-like helicase | / | 0.462 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.461 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.461 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.461 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.460 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2dxx | SAH | Diphthine synthase | / | 0.460 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.460 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.460 | |
| 2owk | SAH | Diphthine synthase | / | 0.460 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.460 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.460 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.460 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.460 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.459 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.459 | |
| 2dxv | SAH | Diphthine synthase | / | 0.459 | |
| 2egb | SAH | Diphthine synthase | / | 0.459 | |
| 2el3 | SAH | Diphthine synthase | / | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.459 | |
| 2y4g | TIR | TamL | / | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.459 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.459 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.459 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.459 | |
| 4lb2 | DM5 | Serum albumin | / | 0.459 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.459 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.458 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.458 | |
| 2egs | SAH | Diphthine synthase | / | 0.458 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.458 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.458 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.458 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.457 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.457 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.457 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.457 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.457 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.457 | |
| 2dsh | SAH | Diphthine synthase | / | 0.457 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.457 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.457 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.457 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.457 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.457 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.457 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.457 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.456 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.456 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2eld | SAH | Diphthine synthase | / | 0.456 | |
| 2gfd | RDA | Endoplasmin | / | 0.456 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.456 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 5a3c | NAD | SIR2 family protein | / | 0.456 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.455 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.455 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.455 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.455 | |
| 2eka | SAH | Diphthine synthase | / | 0.455 | |
| 2emu | SAH | Diphthine synthase | / | 0.455 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.455 | |
| 2p5c | SAH | Diphthine synthase | / | 0.455 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.455 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.455 | |
| 4e2w | JHZ | Methyltransferase | / | 0.455 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.455 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.455 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.454 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.454 | |
| 2p5f | SAH | Diphthine synthase | / | 0.454 | |
| 2z6r | SAH | Diphthine synthase | / | 0.454 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.454 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.454 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.454 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 4ig8 | DTP | 2'-5'-oligoadenylate synthase 1 | / | 0.454 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.454 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.453 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.453 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.453 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.453 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.453 | |
| 2dsg | SAH | Diphthine synthase | / | 0.453 | |
| 2emr | SAH | Diphthine synthase | / | 0.453 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.453 | |
| 3rdq | DTB | Streptavidin | / | 0.453 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.453 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.453 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.453 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.453 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.452 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.452 | |
| 1vce | SAH | Diphthine synthase | / | 0.452 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.452 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.452 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.452 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.452 | |
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 | 0.452 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4yd7 | F5N | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1uay | ADN | Oxidoreductase | / | 0.451 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.451 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.451 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.451 | |
| 2en5 | SAH | Diphthine synthase | / | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.451 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.451 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.451 | |
| 4fnc | HMU | G/T mismatch-specific thymine DNA glycosylase | 3.2.2.29 | 0.451 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.451 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.451 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.450 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.450 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.450 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2el0 | SAH | Diphthine synthase | / | 0.450 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 2p2x | SAH | Diphthine synthase | / | 0.450 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.450 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.450 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.450 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.450 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.449 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2eeq | SAH | Diphthine synthase | / | 0.449 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.449 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.449 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.449 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.449 | |
| 3r88 | 14F | Anthranilate phosphoribosyltransferase | / | 0.449 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4c8e | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.449 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.449 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.448 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.448 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.448 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.448 | |
| 2dsi | SAH | Diphthine synthase | / | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.448 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.448 | |
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.448 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.448 | |
| 4y57 | F63 | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.448 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.447 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.447 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.447 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.447 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.447 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.447 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.447 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.447 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.447 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.447 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.447 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.447 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3zkd | ANP | DNA gyrase subunit B | / | 0.447 | |
| 4b5d | SW4 | Achbp | / | 0.447 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.446 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.446 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.446 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 2ehl | SAH | Diphthine synthase | / | 0.446 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2vf7 | ADP | UvrABC system protein A | / | 0.446 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.446 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.446 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.446 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.446 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 4y0k | NAP | AntE | / | 0.446 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.446 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.446 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.445 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.445 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.445 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.445 | |
| 2e17 | SAH | Diphthine synthase | / | 0.445 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.445 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.445 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.445 | |
| 2pck | SAH | Diphthine synthase | / | 0.445 | |
| 2pcm | SAH | Diphthine synthase | / | 0.445 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.445 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.445 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.445 | |
| 2yy8 | SAM | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.445 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.445 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3zkb | ANP | DNA gyrase subunit B | / | 0.445 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.445 | |
| 4clo | NAP | Pteridine reductase | / | 0.445 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.445 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.445 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.444 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.444 | |
| 2e07 | SAH | Diphthine synthase | / | 0.444 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.444 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 | / | 0.444 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4dt9 | GMP | APH(2'')-Id | / | 0.444 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.444 | |
| 4l16 | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.444 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.444 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1ea0 | FMN | Glutamate synthase [NADPH] large chain | 1.4.1.13 | 0.443 | |
| 1h2h | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.443 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.443 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.443 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3b7k | COA | Acyl-coenzyme A thioesterase 12 | 3.1.2.1 | 0.443 | |
| 3bbd | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | 2.1.1 | 0.443 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.443 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 4bmp | FMN | Protein NrdI | / | 0.443 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.443 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.443 | |
| 1g28 | FMN | PHY3 | / | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1s16 | ANP | DNA topoisomerase 4 subunit B | / | 0.442 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.442 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.442 | |
| 2huq | SAH | Diphthine synthase | / | 0.442 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 3gol | XND | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.442 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.442 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.442 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 5 | / | 0.441 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.441 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.441 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.441 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.441 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.441 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.441 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.441 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3u7l | UDB | Peptide deformylase | / | 0.441 | |
| 3vo8 | GDP | Cell division protein FtsZ | / | 0.441 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.441 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.441 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 4mub | OAQ | Sulfotransferase oxamniquine resistance protein | / | 0.441 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.441 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.440 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.440 | |
| 1m76 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.440 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.440 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.440 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.440 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.440 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.440 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.440 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4kxj | P34 | Nucleoprotein | / | 0.440 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.440 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.440 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.440 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.440 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 |