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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hs8FMN12-oxophytodienoate reductase 31.3.1.42

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2hs8FMN12-oxophytodienoate reductase 31.3.1.421.000
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.646
1q45FMN12-oxophytodienoate reductase 31.3.1.420.639
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.621
1icpFMN12-oxophytodienoate reductase 11.3.1.420.612
1icqFMN12-oxophytodienoate reductase 11.3.1.420.593
4tmbFMNOld yellow enzyme/0.571
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.568
3f03FMNPentaerythritol tetranitrate reductase/0.564
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.558
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.558
1icsFMN12-oxophytodienoate reductase 11.3.1.420.555
2abbFMNPentaerythritol tetranitrate reductase/0.548
3p74FMNPentaerythritol tetranitrate reductase/0.543
1h50FMNPentaerythritol tetranitrate reductase/0.539
4rnuFMNNADPH dehydrogenase 11.6.99.10.538
1vyrFMNPentaerythritol tetranitrate reductase/0.531
4rnvFMNNADPH dehydrogenase 11.6.99.10.529
1h63FMNPentaerythritol tetranitrate reductase/0.528
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.527
3p82FMNPentaerythritol tetranitrate reductase/0.525
3p62FMNPentaerythritol tetranitrate reductase/0.520
4jicFMNGTN Reductase/0.520
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.510
1h51FMNPentaerythritol tetranitrate reductase/0.502
3gkaFMNN-ethylmaleimide reductase/0.489
4rnwFMNNADPH dehydrogenase 11.6.99.10.484
4e2bFMNDehydrogenase/0.482
1o9bNAIQuinate/shikimate dehydrogenase/0.479
3atzFMNProstaglandin F2a synthase/0.478
4e2dFMNDehydrogenase/0.475
3l5lFMNXenobiotic reductase/0.474
3p8jFMNPentaerythritol tetranitrate reductase/0.469
1bwkFMNNADPH dehydrogenase 11.6.99.10.468
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.461
1oyaFMNNADPH dehydrogenase 11.6.99.10.460
1z44FMNNADPH dehydrogenase/0.460
3atyFMNProstaglandin F2a synthase/0.454
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.454
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1z41FMNNADPH dehydrogenase/0.452
1bwsNDPGDP-L-fucose synthase/0.449
3n19FNRXenobiotic reductase/0.446
4awtFMNNADH:flavin oxidoreductase Sye1/0.445
4df2FMNNADPH dehydrogenase/0.445
4h6kFMNNADPH dehydrogenase 11.6.99.10.445
1vi2NADQuinate/shikimate dehydrogenase/0.444
1bwlFMNNADPH dehydrogenase 11.6.99.10.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440