sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 1.000 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.594 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.584 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.582 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.578 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.534 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.517 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.514 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.499 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.499 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.488 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.482 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.474 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.462 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.462 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.461 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.461 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.455 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.444 |