sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	1.000
1f17	NAI	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.639
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.620
3hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.609
3had	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.601
1lso	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.588
4kuh	CAA	3-hydroxybutyryl-CoA dehydrogenase	/	0.517
1f12	3HC	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.506
4kug	NAD	3-hydroxybutyryl-CoA dehydrogenase	/	0.460
3zw9	NAD	Peroxisomal bifunctional enzyme	1.1.1.35	0.459
4pzd	NAD	3-Hydroxyacyl-CoA dehydrogenase	/	0.440