sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gz8 | F3F | Orf1a polyprotein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2gz8 | F3F | Orf1a polyprotein | / | 1.000 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.612 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.574 | |
| 2qiq | CYV | Replicase polyprotein 1ab | / | 0.568 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.472 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.465 | |
| 2owf | SAH | Diphthine synthase | / | 0.461 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.450 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.445 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.443 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.442 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 |