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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gpvOHTEstrogen-related receptor gamma

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2gpvOHTEstrogen-related receptor gamma/1.000
1s9qOHTEstrogen-related receptor gamma/0.562
2jf9OHTEstrogen receptor/0.480
2p7zOHTEstrogen-related receptor gamma/0.478
1yinCM3Estrogen receptor/0.471
1s9pDESEstrogen-related receptor gamma/0.470
1xp6AIUEstrogen receptor/0.460
1errRALEstrogen receptor/0.459
2gpuOHTEstrogen-related receptor gamma/0.453
2ewpTXFEstrogen-related receptor gamma/0.452
4a862ANMajor pollen allergen Bet v 1-A/0.452
1sj0E4DEstrogen receptor/0.451
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.442