sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 1.000 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.646 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.640 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.610 | |
| 4jic | FMN | GTN Reductase | / | 0.490 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.466 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.465 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.464 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 |