sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2gew	FAD	Cholesterol oxidase	1.1.3.6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2gew	FAD	Cholesterol oxidase	1.1.3.6	1.000
3gyj	FAD	Cholesterol oxidase	1.1.3.6	0.669
3b6d	FAE	Cholesterol oxidase	1.1.3.6	0.660
1b8s	FAD	Cholesterol oxidase	1.1.3.6	0.636
3cnj	FAD	Cholesterol oxidase	1.1.3.6	0.626
4u2t	FAD	Cholesterol oxidase	1.1.3.6	0.619
1n1p	FAD	Cholesterol oxidase	1.1.3.6	0.618
4xwr	FAD	Cholesterol oxidase	1.1.3.6	0.618
1n4w	FAD	Cholesterol oxidase	1.1.3.6	0.616
4xxg	FAD	Cholesterol oxidase	1.1.3.6	0.615
1b4v	FAD	Cholesterol oxidase	1.1.3.6	0.613
1ijh	FAD	Cholesterol oxidase	1.1.3.6	0.613
4rek	FAD	Cholesterol oxidase	1.1.3.6	0.605
1cbo	FAD	Cholesterol oxidase	1.1.3.6	0.602
1n4v	FAD	Cholesterol oxidase	1.1.3.6	0.581
3gyi	FAD	Cholesterol oxidase	1.1.3.6	0.562