sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2g96	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2g96	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12	1.000
2gvj	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.522
4m6p	20R	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.512
4m6q	20T	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.497
4lww	LWW	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.479
2gvg	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.478
4jnm	1LJ	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.476
4kfp	1R7	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.472
2h3d	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.466
4lva	20M	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.466
4jr5	1LS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.459
4o28	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.456
4kfn	1QR	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.440