Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2g86UMPThymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2g86UMPThymidylate synthase/1.000
2g89UMPThymidylate synthase/0.667
2g8aUMPThymidylate synthase/0.655
1tsyUMPThymidylate synthase/0.627
1njdUMPThymidylate synthase/0.603
1njeDCMThymidylate synthase/0.601
1tsxUMPThymidylate synthase/0.572
1bp6UMPThymidylate synthase/0.570
1jmgUMPThymidylate synthase/0.564
2tdmUMPThymidylate synthase/0.557
1vzbUMPThymidylate synthase/0.542
1njbUMPThymidylate synthase/0.537
1tsvUMPThymidylate synthase/0.537
1thyUMPThymidylate synthase/0.516
1bpjUMPThymidylate synthase/0.508
1njcDCMThymidylate synthase/0.498
1vzaUMPThymidylate synthase/0.494
1lcbTMPThymidylate synthase/0.478
1lcbDHFThymidylate synthase/0.470
1jmfUMPThymidylate synthase/0.466
1bidUMPThymidylate synthase/0.458
1njaDCMThymidylate synthase/0.440