sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2fwn	TDP	Benzoylformate decarboxylase	4.1.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2fwn	TDP	Benzoylformate decarboxylase	4.1.1.7	1.000
5dgt	TZD	Benzoylformate decarboxylase	4.1.1.7	0.683
4ju8	TZD	Benzoylformate decarboxylase	4.1.1.7	0.637
1bfd	TPP	Benzoylformate decarboxylase	4.1.1.7	0.611
4mq5	TPP	Benzoylformate decarboxylase	4.1.1.7	0.611
4ju9	TZD	Benzoylformate decarboxylase	4.1.1.7	0.581
4qel	TZD	Benzoylformate decarboxylase	4.1.1.7	0.572
4juf	TPP	Benzoylformate decarboxylase	4.1.1.7	0.570
4k9n	TZD	Benzoylformate decarboxylase	4.1.1.7	0.566
4jub	TPP	Benzoylformate decarboxylase	4.1.1.7	0.538
3fzn	D7K	Benzoylformate decarboxylase	4.1.1.7	0.536
4jd5	TZD	Benzoylformate decarboxylase	4.1.1.7	0.519
4mzx	TZD	Benzoylformate decarboxylase	4.1.1.7	0.504
4gm0	TZD	Benzoylformate decarboxylase	4.1.1.7	0.489
4k9p	TPP	Benzoylformate decarboxylase	4.1.1.7	0.488
3ieu	GDP	GTPase Era	/	0.474
1la2	NAD	Inositol-3-phosphate synthase	5.5.1.4	0.442
4gm1	TZD	Benzoylformate decarboxylase	4.1.1.7	0.440