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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fkeFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.8

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2fkeFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.81.000
1fkd818Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.814
4dz2FK5Peptidyl-prolyl cis-trans isomerase/0.662
1fkjFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.660
1fkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.643
1a7xFKAPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.639
1fkiSB1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.637
1j4hSUBPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.635
4dh0MR8Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.633
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.631
1bkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.630
1fklRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.629
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.627
1c9hRAPPeptidyl-prolyl cis-trans isomerase FKBP1B5.2.1.80.626
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.626
2dg3RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.624
2dg9RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.618
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.608
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.606
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.606
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.604
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.604
4qt3RAPPeptidylprolyl isomerase/0.599
1q6iFK5FKBP-type peptidyl-prolyl cis-trans isomerase FkpA5.2.1.80.596
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.595
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.593
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.578
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.572
1fkhSBXPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.571
2vn1FK5Peptidylprolyl isomerase/0.569
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.565
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.565
4jfi1KTPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.565
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.563
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.563
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.560
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.560
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.560
4drp0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.560
4drkI63Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.559
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.548
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.546
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.546
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.535
2xuoTZ4Acetylcholinesterase3.1.1.70.523
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.519
4j4nD44Peptidylprolyl isomerase/0.511
1h22E10Acetylcholinesterase3.1.1.70.504
1eveE20Acetylcholinesterase3.1.1.70.503
3pkaY02Methionine aminopeptidase 2/0.503
4gcmNAPThioredoxin reductase1.8.1.90.502
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.499
3pkeY10Methionine aminopeptidase 2/0.497
4rp8ASCAscorbate-specific PTS system EIIC component/0.497
1w76GNTAcetylcholinesterase3.1.1.70.496
3iu8T03Methionine aminopeptidase 2/0.496
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.496
4arbC57Acetylcholinesterase3.1.1.70.495
1u65CP0Acetylcholinesterase3.1.1.70.494
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.493
4zwpM44Xaa-Pro dipeptidase3.4.13.90.492
2cekN8TAcetylcholinesterase3.1.1.70.491
3t0iSAHPutative methyltransferase/0.491
4a862ANMajor pollen allergen Bet v 1-A/0.491
3juoAJDPhenazine biosynthesis protein A/B/0.490
3zv7NHGAcetylcholinesterase3.1.1.70.490
1w4lGL8Acetylcholinesterase3.1.1.70.489
2p99YE6Methionine aminopeptidase/0.488
2gyuHI6Acetylcholinesterase3.1.1.70.486
2whqHI6Acetylcholinesterase3.1.1.70.486
3k8q22APurine nucleoside phosphorylase2.4.2.10.486
2w6cBM4Acetylcholinesterase3.1.1.70.485
3pkcY08Methionine aminopeptidase 2/0.485
3w3nRX8Toll-like receptor 8/0.485
4a86H35Major pollen allergen Bet v 1-A/0.485
2q94A04Methionine aminopeptidase/0.484
4fljY08Methionine aminopeptidase 1/0.484
2oazI96Methionine aminopeptidase 2/0.483
3mytEQUSteroid Delta-isomerase5.3.3.10.483
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.483
1yw8A75Methionine aminopeptidase 2/0.482
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.482
2xupTZ5Acetylcholinesterase3.1.1.70.482
5ah5LSSLeucine--tRNA ligase/0.482
2avxHTFRegulatory protein SdiA/0.481
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.481
4a8v2ANMajor pollen allergen Bet v 1-J/0.481
1t7o152Carnitine O-acetyltransferase2.3.1.70.480
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.480
2dxfGNPNucleoside diphosphate kinase2.7.4.60.479
3dc3AZMCarbonic anhydrase 24.2.1.10.479
3pkbY16Methionine aminopeptidase 2/0.479
1p4r354Bifunctional purine biosynthesis protein PURH2.1.2.30.478
1w6rGNTAcetylcholinesterase3.1.1.70.478
2zbwFADFerredoxin--NADP reductase/0.478
4b64NAPL-ornithine N(5)-monooxygenase/0.478
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
1gpnHUBAcetylcholinesterase3.1.1.70.477
1odcA8BAcetylcholinesterase3.1.1.70.477
2r8pT6FTransketolase 1/0.477
1qtiGNTAcetylcholinesterase3.1.1.70.476
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.476
1el4CTZObelin/0.475
1uhhCZPAequorin-2/0.475
1w6jR71Lanosterol synthase5.4.99.70.475
2j3qTFLAcetylcholinesterase3.1.1.70.475
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.475
3igpDT7Carbonic anhydrase 24.2.1.10.475
3qbjNXZDipeptidyl peptidase 4/0.475
1r58AO5Methionine aminopeptidase 2/0.474
2dxdANPNucleoside diphosphate kinase2.7.4.60.474
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.474
2ga2A19Methionine aminopeptidase 2/0.474
2xufTZ4Acetylcholinesterase3.1.1.70.474
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
1xvaSAMGlycine N-methyltransferase2.1.1.200.473
3b4p3B4Phenazine biosynthesis protein A/B/0.473
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.473
3i0oSMISpectinomycin phosphotransferase/0.473
3own3OXRenin3.4.23.150.473
4b67NAPL-ornithine N(5)-monooxygenase/0.473
4jiq1L5GTN Reductase/0.473
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.472
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.472
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
3c3xNAPEugenol synthase 11.1.1.3180.472
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.472
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.472
4a802ANMajor pollen allergen Bet v 1-A/0.472
1r5gAO1Methionine aminopeptidase 2/0.471
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.471
3ou2SAHSAM-dependent methyltransferase/0.471
3q8uADPNucleoside diphosphate kinase/0.471
3rtnRTNBeta-secretase 13.4.23.460.471
4n1gCEIObelin/0.471
1lbm137N-(5'-phosphoribosyl)anthranilate isomerase5.3.1.240.470
1zgbA1EAcetylcholinesterase3.1.1.70.470
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.470
3ivcFG4Pantothenate synthetase6.3.2.10.470
3nd6ATPPhosphopantetheine adenylyltransferase/0.470
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3iu7FCDMethionine aminopeptidase 2/0.469
1dp2LPBThiosulfate sulfurtransferase/0.468
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.468
2ewvADPTwitching motility protein PilT/0.468
2p98YE7Methionine aminopeptidase/0.468
3f8sPF2Dipeptidyl peptidase 4/0.468
3junAJDPhenazine biosynthesis protein A/B/0.468
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
1gaxVAAValine--tRNA ligase6.1.1.90.467
2xugTZ4Acetylcholinesterase3.1.1.70.467
4a87NARMajor pollen allergen Bet v 1-A/0.467
4gddNAIUDP-galactopyranose mutase/0.467
1dx6GNTAcetylcholinesterase3.1.1.70.466
1h60STRPentaerythritol tetranitrate reductase/0.466
1yw9A84Methionine aminopeptidase 2/0.466
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.466
2e0nSAHPrecorrin-2 C20-methyltransferase/0.466
2ea2F77Methionine aminopeptidase 2/0.466
3d27W29Methionine aminopeptidase/0.466
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.466
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.465
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.465
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.465
2evmFC2Methionine aminopeptidase/0.465
2gvdFKPAdenylate cyclase type 2/0.465
2gvdFKPAdenylate cyclase type 5/0.465
2xuhTZ4Acetylcholinesterase3.1.1.70.465
3g0gRUMDipeptidyl peptidase 4/0.465
3p8hP8HLethal(3)malignant brain tumor-like protein 1/0.465
3vilSA0Beta-glucosidase/0.465
4uugPXGBranched-chain amino acid aminotransferase, putative/0.465
1e66HUXAcetylcholinesterase3.1.1.70.464
3rsv3RSBeta-secretase 13.4.23.460.464
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.464
1yw7A41Methionine aminopeptidase 2/0.463
2a3bCFFEndochitinase B13.2.1.140.463
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
2ea4F79Methionine aminopeptidase 2/0.463
2fhkMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.463
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.463
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.463
3l7gM44Xaa-Pro dipeptidase3.4.13.90.463
3myqE27Carbonic anhydrase 24.2.1.10.463
3qviK95HAP protein/0.463
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.463
4bf6X0QCarbonic anhydrase 24.2.1.10.463
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.463
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.463
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.463
1q84TZ4Acetylcholinesterase3.1.1.70.462
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.462
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.462
2g1n1IGRenin3.4.23.150.462
2jf0HBPAcetylcholinesterase3.1.1.70.462
3m2nJ74Carbonic anhydrase 24.2.1.10.462
4fweFADLysine-specific histone demethylase 1B10.462
4m0f1YKAcetylcholinesterase3.1.1.70.462
5kwvANPPantothenate synthetase/0.462
1r5hAO2Methionine aminopeptidase 2/0.461
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.461
2qimZEAClass 10 plant pathogenesis-related protein/0.461
3ei8PL5LL-diaminopimelate aminotransferase, chloroplastic/0.461
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.461
1icqFMN12-oxophytodienoate reductase 11.3.1.420.460
1lc3NADBiliverdin reductase A1.3.1.240.460
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.460
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.460
3iu9T07Methionine aminopeptidase 2/0.460
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.460
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.460
3qeoLLTDeoxycytidine kinase2.7.1.740.460
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.460
1bnnAL1Carbonic anhydrase 24.2.1.10.459
1culFOKAdenylate cyclase type 2/0.459
1culFOKAdenylate cyclase type 5/0.459
1j49NADD-lactate dehydrogenase1.1.1.280.459
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.459
2ckmAA7Acetylcholinesterase3.1.1.70.459
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.459
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.459
3h3t16HCollagen type IV alpha-3-binding protein/0.459
3sxjSAMPutative methyltransferase/0.459
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.459
4b63NAPL-ornithine N(5)-monooxygenase/0.459
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.459
5i2fBS5Histidine triad nucleotide-binding protein 130.459
7stdCRPScytalone dehydratase4.2.1.940.459
2cv2GSUGlutamate--tRNA ligase6.1.1.170.458
2flhZEACytokinin-specific binding protein/0.458
2ha6SCKAcetylcholinesterase3.1.1.70.458
2wu4HBPAcetylcholinesterase3.1.1.70.458
2wzySQXSoluble acetylcholine receptor/0.458
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.458
4hxx1AYMethionine aminopeptidase 1/0.458
4o7gASCProbable transmembrane ascorbate ferrireductase 21.16.5.10.458
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.458
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.458
5k7wSAHN6-adenosine-methyltransferase 70 kDa subunit/0.458
4u163C0Muscarinic acetylcholine receptor M3/0.458
1cnfFADNitrate reductase [NADH]1.7.1.10.457
1n5qTNCActVA 6 protein/0.457
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
2x7tWZBCarbonic anhydrase 24.2.1.10.457
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.457
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.457
4fllYZ6Methionine aminopeptidase 1/0.457
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.456
1lkeDOGBilin-binding protein/0.456
1pfyMSPMethionine--tRNA ligase6.1.1.100.456
2a5c8DAAvidin/0.456
2a9y26AAdenosine kinase2.7.1.200.456
2gg2U12Methionine aminopeptidase/0.456
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.456
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.456
3hl4CDCCholine-phosphate cytidylyltransferase A/0.456
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.456
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.456
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.456
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.456
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.456
4kbyC2EStimulator of interferon genes protein/0.456
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.456
4x5gFOLDihydrofolate reductase1.5.1.30.456
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.455
1w34FADFerredoxin--NADP reductase1.18.1.20.455
2jn3JN3Fatty acid-binding protein, liver/0.455
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.455
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.455
3m40J45Carbonic anhydrase 24.2.1.10.455
3m98E02Carbonic anhydrase 24.2.1.10.455
3n4bWWZCarbonic anhydrase 24.2.1.10.455
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.455
4psbGA3Cytokinin-specific binding protein/0.455
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.455
2evcFC3Methionine aminopeptidase/0.454
2rgu356Dipeptidyl peptidase 4/0.454
3nu03TUDihydrofolate reductase1.5.1.30.454
4araC56Acetylcholinesterase3.1.1.70.454
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.454
1acjTHAAcetylcholinesterase3.1.1.70.453
1cjuFOKAdenylate cyclase type 2/0.453
1cjuFOKAdenylate cyclase type 5/0.453
1fmlRTLRetinol dehydratase/0.453
1kwrSG2Carbonic anhydrase 24.2.1.10.453
1pydTDPPyruvate decarboxylase isozyme 1/0.453
1rszDIHPurine nucleoside phosphorylase2.4.2.10.453
1rzuADPGlycogen synthase 12.4.1.210.453
2abaSTRPentaerythritol tetranitrate reductase/0.453
2h4nAZMCarbonic anhydrase 24.2.1.10.453
2q93B21Methionine aminopeptidase/0.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.453
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.453
3q7fED2Uncharacterized protein/0.453
4cb4MGTPolymerase basic protein 2/0.453
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.453
1xnzFCDMethionine aminopeptidase/0.452
1xuzMMNCapsule biosynthesis protein/0.452
2dxiATPGlutamate--tRNA ligase6.1.1.170.452
2ohjFMNType A flavoprotein FprA10.452
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.452
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.452
3h06VBPGlutamate receptor 2/0.452
3vjlW94Dipeptidyl peptidase 4/0.452
4e2wJHZMethyltransferase/0.452
4ey6GNTAcetylcholinesterase3.1.1.70.452
4flkY10Methionine aminopeptidase 1/0.452
4iktTFVMethionine aminopeptidase 1/0.452
4nqgCZHMitrocomin/0.452
2ffqGSPRas-related protein Rab-6B/0.451
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.451
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.451
2weoFBWCarbonic anhydrase 24.2.1.10.451
3apwDP0Alpha-1-acid glycoprotein 2/0.451
3b4fTUOCarbonic anhydrase 24.2.1.10.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3p80P80Pentaerythritol tetranitrate reductase/0.451
3pkdY10Methionine aminopeptidase 2/0.451
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3wqmB29Diterpene synthase3.1.7.80.451
4j0v1H7Beta-secretase 13.4.23.460.451
4kq1U5PGlycogen [starch] synthase/0.451
4p9dTMPDeoxycytidylate deaminase/0.451
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.451
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.450
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.450
1zgcA2EAcetylcholinesterase3.1.1.70.450
2h15B19Carbonic anhydrase 24.2.1.10.450
2q92B23Methionine aminopeptidase/0.450
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.450
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.450
3mhiJ90Carbonic anhydrase 24.2.1.10.450
3w0tHPULactoylglutathione lyase4.4.1.50.450
5c3rHMUThymine dioxygenase/0.450
3ny9JSZBeta-2 adrenergic receptor/0.450
1c7oPPGHemolysin/0.449
1jf0CZHObelin/0.449
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.449
2npfMOUElongation factor 2/0.449
3dcsMZMCarbonic anhydrase 24.2.1.10.449
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.449
3h3r14HCollagen type IV alpha-3-binding protein/0.449
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.449
4a16H34Acetylcholinesterase3.1.1.70.449
4b66NAPL-ornithine N(5)-monooxygenase/0.449
4b7zQ4QAcetylcholinesterase3.1.1.70.449
4ey7E20Acetylcholinesterase3.1.1.70.449
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.449
6stdMS2Scytalone dehydratase4.2.1.940.449
7req2CPMethylmalonyl-CoA mutase large subunit5.4.99.20.449
1bwlFMNNADPH dehydrogenase 11.6.99.10.448
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1nhkCMPNucleoside diphosphate kinase2.7.4.60.448
1o9bNAIQuinate/shikimate dehydrogenase/0.448
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.448
1vyqDUXDeoxyuridine 5'-triphosphate nucleotidohydrolase/0.448
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.448
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.448
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.448
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4imgNGFN-acetylneuraminate lyase/0.448
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.448
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.447
1ivsVAAValine--tRNA ligase6.1.1.90.447
1j9zFADNADPH--cytochrome P450 reductase/0.447
1mk1APRMutT/nudix family protein/0.447
2b58COADiamine acetyltransferase 1/0.447
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.447
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.447
2stdCRPScytalone dehydratase4.2.1.940.447
2wcgMT5Glucosylceramidase3.2.1.450.447
2zevIPEGeranylgeranyl pyrophosphate synthase/0.447
3c1oNAPEugenol synthase/0.447
3ekuCY9Actin-5C/0.447
3h3qH13Collagen type IV alpha-3-binding protein/0.447
3rvhHQ2Lysine-specific demethylase 4A1.14.110.447
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.447
5iefNBVNeutral alpha-glucosidase AB3.2.1.840.447
1g1dFSBCarbonic anhydrase 24.2.1.10.446
1h6dNDPGlucose--fructose oxidoreductase1.1.99.280.446
1icpFMN12-oxophytodienoate reductase 11.3.1.420.446
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.446
1wm1PTBProline iminopeptidase3.4.11.50.446
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.446
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2fbwCBESuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.446
2fbwCBESuccinate dehydrogenase cytochrome b, large subunit/0.446
2ggbU17Methionine aminopeptidase/0.446
2gywOBIAcetylcholinesterase3.1.1.70.446
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.446
3kkzSAMUncharacterized protein/0.446
3m5eJDRCarbonic anhydrase 24.2.1.10.446
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4s1iPLPPyridoxal kinase, putative/0.446
4xczT3QQdtf/0.446
5fmmMGTPolymerase basic protein 2/0.446
1ej3CZHAequorin-2/0.445
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.445
2eu3FF3Carbonic anhydrase 24.2.1.10.445
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.445
2zs9ADPPantothenate kinase2.7.1.330.445
3cow52HPantothenate synthetase6.3.2.10.445
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.445
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4e31JHZMethyltransferase/0.445
4iifCTSBeta-glucosidase 13.2.1.210.445
1oknSTBCarbonic anhydrase 24.2.1.10.444
1qy2IPZMajor urinary protein 1/0.444
1ttm667Carbonic anhydrase 24.2.1.10.444
1wklATPNucleoside diphosphate kinase/0.444
2lfoGCHFatty acid-binding protein, liver/0.444
2webPP4Penicillopepsin-13.4.23.200.444
2zi53L1Deoxycytidine kinase2.7.1.740.444
3aosJH2Hemolymph juvenile hormone binding protein/0.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3eft3BSCarbonic anhydrase 24.2.1.10.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3juqAJDPhenazine biosynthesis protein A/B/0.444
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3pzcGAPAmino acid--[acyl-carrier-protein] ligase 16.2.1.n20.444
3stdMQ0Scytalone dehydratase4.2.1.940.444
4b68NAPL-ornithine N(5)-monooxygenase/0.444
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.444
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
4l5b1UXDeoxycytidine kinase2.7.1.740.444
1ay0TPPTransketolase 12.2.1.10.443
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.443
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.443
1yzqGNPRas-related protein Rab-6A/0.443
1z6tADPApoptotic protease-activating factor 1/0.443
2aj4ANPGalactokinase2.7.1.60.443
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.443
2xukTZ5Acetylcholinesterase3.1.1.70.443
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3o76GTBGlutathione S-transferase P 12.5.1.180.443
3t85SG7Carbonic anhydrase 24.2.1.10.443
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.443
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.442
1jf2CZHObelin/0.442
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.442
1oz0MS1Bifunctional purine biosynthesis protein PURH2.1.2.30.442
1x1bSAHC-20 methyltransferase/0.442
2a4xBLMMitomycin-binding protein/0.442
2b3vACODiamine acetyltransferase 1/0.442
2po3T4K4-dehydrase/0.442
3c15FOKAdenylate cyclase type 2/0.442
3c15FOKAdenylate cyclase type 5/0.442
3dcwEZLCarbonic anhydrase 24.2.1.10.442
3rviRVIBeta-secretase 13.4.23.460.442
4askK0ILysine-specific demethylase 6B1.14.110.442
4jq4IMNAldo-keto reductase family 1 member C2/0.442
4kap1QVCarbonic anhydrase 24.2.1.10.442
1aqv0HGGlutathione S-transferase P2.5.1.180.441
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1cjtFOKAdenylate cyclase type 2/0.441
1cjtFOKAdenylate cyclase type 5/0.441
1gky5GPGuanylate kinase2.7.4.80.441
1h51FMNPentaerythritol tetranitrate reductase/0.441
1hnaGDNGlutathione S-transferase Mu 22.5.1.180.441
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.441
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.441
1pl6572Sorbitol dehydrogenase1.1.1.140.441
2h3wCOACarnitine O-acetyltransferase2.3.1.70.441
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.441
2plmSIB5-methylthioadenosine/S-adenosylhomocysteine deaminase3.5.4.280.441
2rehFADNitroalkane oxidase1.7.3.10.441
2xlrFADPutative flavin-containing monooxygenase/0.441
2xuiTZ5Acetylcholinesterase3.1.1.70.441
3dr4G4MGDP-perosamine synthase/0.441
3fui812Leukotriene A-4 hydrolase3.3.2.60.441
3mauPLRPutative sphingosine-1-phosphate lyase/0.441
3rthRTHBeta-secretase 13.4.23.460.441
3sfy3FYUncharacterized protein/0.441
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.441
4bfwZVWPantothenate kinase2.7.1.330.441
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.441
1bwkFMNNADPH dehydrogenase 11.6.99.10.440
1n77ATPGlutamate--tRNA ligase6.1.1.170.440
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.440
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.440
1x2bSTXProline iminopeptidase3.4.11.50.440
2b82ADNClass B acid phosphatase3.1.3.20.440
2gg9U16Methionine aminopeptidase/0.440
2il2LIXRenin3.4.23.150.440
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.440
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.440
2xi4AFTAcetylcholinesterase3.1.1.70.440
3b6pTMPThree-prime repair exonuclease 13.1.11.20.440
3d9zD9ZCarbonic anhydrase 24.2.1.10.440
3fw3ETSCarbonic anhydrase 44.2.1.10.440
3i978DRNeuropilin-1/0.440
3ie3N11Glutathione S-transferase P2.5.1.180.440
3lzzGDPUncharacterized protein/0.440
3nxtD2EDihydrofolate reductase1.5.1.30.440
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.440
4d2dALA_ALA_ALADi-or tripeptide:H+ symporter/0.440
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4ikrPVPMethionine aminopeptidase 1/0.440
4jq3NAPAldo-keto reductase family 1 member C2/0.440
4l1xNAPAldo-keto reductase family 1 member C2/0.440
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440
5k7uSAMN6-adenosine-methyltransferase 70 kDa subunit/0.440