sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.580 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.536 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.527 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.522 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.520 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.513 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.511 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.493 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.492 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.490 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.490 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.488 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.483 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.483 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.482 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.482 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.477 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.474 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.471 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.470 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.468 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.463 | |
| 3v4f | GNP | GTPase HRas | / | 0.459 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.457 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.456 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.453 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.453 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.452 | |
| 4nyi | GNP | GTPase HRas | / | 0.449 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.448 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.446 | |
| 3oiv | GNP | GTPase HRas | / | 0.446 | |
| 3ddc | GNP | GTPase HRas | / | 0.443 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.443 | |
| 2rge | GNP | GTPase HRas | / | 0.442 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.442 | |
| 4mit | GTP | Rho-related protein racC | / | 0.442 |