sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fhl | BNI | Avidin-related protein 4/5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2fhl | BNI | Avidin-related protein 4/5 | / | 1.000 | |
| 2uyw | BTN | Avd protein | / | 0.591 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.581 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.540 | |
| 1avd | BTN | Avidin | / | 0.518 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.514 | |
| 2avi | BTN | Avidin | / | 0.497 | |
| 4bx7 | B4F | Streptavidin | / | 0.478 | |
| 2uz2 | BTN | Avd protein | / | 0.475 | |
| 2c4i | BTN | Avidin | / | 0.471 | |
| 3vhi | VHI | Avidin | / | 0.470 | |
| 4gda | BTN | Streptavidin | / | 0.467 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.461 | |
| 2rtf | BTN | Streptavidin | / | 0.459 | |
| 2izh | BTN | Streptavidin | / | 0.458 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.456 | |
| 1mk5 | BTN | Streptavidin | / | 0.455 | |
| 1sri | DMB | Streptavidin | / | 0.453 | |
| 2rti | GLL | Streptavidin | / | 0.452 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.451 | |
| 2izf | BTN | Streptavidin | / | 0.450 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 1srf | MTB | Streptavidin | / | 0.449 | |
| 1sre | HAB | Streptavidin | / | 0.447 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.447 | |
| 1rxh | BNI | Streptavidin | / | 0.446 | |
| 3up0 | D7S | aceDAF-12 | / | 0.446 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.446 | |
| 2rte | BTN | Streptavidin | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 3vgw | NVZ | Avidin | / | 0.442 | |
| 4dne | DTB | Streptavidin | / | 0.442 | |
| 2r9w | 23C | Beta-lactamase | 3.5.2.6 | 0.440 |