sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f8p | CEI | Obelin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2f8p | CEI | Obelin | / | 1.000 | |
| 4mry | CEI | Obelin | / | 0.494 | |
| 3b9l | AZZ | Serum albumin | / | 0.466 | |
| 3cse | N22 | Uncharacterized protein | / | 0.463 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2bxq | IMN | Serum albumin | / | 0.457 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.454 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.454 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.452 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.449 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.449 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.449 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.446 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.445 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 4c9w | VGH | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.440 |