sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f6r | ACO | Bifunctional coenzyme A synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 1.000 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.483 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.459 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.455 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.452 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.452 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.451 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.449 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.448 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.441 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 |