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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.41.000
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.595
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.576
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.565
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.553
2yquFADDihydrolipoyl dehydrogenase/0.548
2eq9FADDihydrolipoyl dehydrogenase/0.536
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.519
4jq9FADDihydrolipoyl dehydrogenase/0.514
3ladFADDihydrolipoyl dehydrogenase/0.490
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.470
2eq6FADDihydrolipoyl dehydrogenase/0.465
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.461
3urhFADDihydrolipoyl dehydrogenase/0.446
1zk7FADMercuric reductase1.16.1.10.442
1zx9FADMercuric reductase1.16.1.10.441