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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2excJNKMitogen-activated protein kinase 102.7.11.24

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2excJNKMitogen-activated protein kinase 102.7.11.241.000
2b1pAIZMitogen-activated protein kinase 102.7.11.240.692
3ttjJBIMitogen-activated protein kinase 102.7.11.240.645
3ttiKBIMitogen-activated protein kinase 102.7.11.240.618
2zdt46CMitogen-activated protein kinase 102.7.11.240.588
3cgfJNFMitogen-activated protein kinase 102.7.11.240.572
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.558
2o0uC0MMitogen-activated protein kinase 102.7.11.240.553
4ux9ANPMitogen-activated protein kinase 82.7.11.240.550
1pmn984Mitogen-activated protein kinase 102.7.11.240.549
2o2u738Mitogen-activated protein kinase 102.7.11.240.541
5awmANPStress-activated protein kinase JNK2.7.11.240.541
2p33J07Mitogen-activated protein kinase 102.7.11.240.535
3eljGS7Mitogen-activated protein kinase 82.7.11.240.530
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.530
3kvxFMYMitogen-activated protein kinase 102.7.11.240.527
1bygSTUTyrosine-protein kinase CSK/0.525
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.525
4i22IREEpidermal growth factor receptor2.7.10.10.523
3cgoJNOMitogen-activated protein kinase 102.7.11.240.521
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.521
4jqeANPCasein kinase II subunit alpha2.7.11.10.518
4hyu1BKMitogen-activated protein kinase 82.7.11.240.517
1pmv537Mitogen-activated protein kinase 102.7.11.240.515
4jbqVX6Aurora kinase A2.7.11.10.515
4wsqKSAAP2-associated protein kinase 12.7.11.10.514
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.513
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.512
3oom507Activin receptor type-12.7.11.300.512
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.511
3k5uPFQAurora kinase A2.7.11.10.510
4e730NRMitogen-activated protein kinase 82.7.11.240.508
1jpaANPEphrin type-B receptor 22.7.10.10.507
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.507
4bgg844Activin receptor type-12.7.11.300.507
2h96893Mitogen-activated protein kinase 82.7.11.240.506
3gxlQIGTGF-beta receptor type-12.7.11.300.506
4gmy0X5Tyrosine-protein kinase JAK2/0.505
2qo9ANPEphrin type-A receptor 32.7.10.10.504
5cvhADPCasein kinase II subunit alpha2.7.11.10.504
5e8wSTUTGF-beta receptor type-12.7.11.300.504
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.503
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.503
4zseANPEpidermal growth factor receptor2.7.10.10.503
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.502
2xrwANPMitogen-activated protein kinase 82.7.11.240.502
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.502
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.501
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.501
3gubGUBDeath-associated protein kinase 12.7.11.10.499
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.499
4j97ACPFibroblast growth factor receptor 2/0.498
5e8xSTUTGF-beta receptor type-12.7.11.300.498
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.497
3vquO22Dual specificity protein kinase TTK2.7.12.10.497
4c4f7CEDual specificity protein kinase TTK2.7.12.10.497
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.497
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.496
4aotGW8Serine/threonine-protein kinase 102.7.11.10.496
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.495
3ggfGVDSerine/threonine-protein kinase 26/0.495
2henADPEphrin type-B receptor 22.7.10.10.494
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.494
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.493
4c4h7RODual specificity protein kinase TTK2.7.12.10.493
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.493
3w18N13Aurora kinase A2.7.11.10.492
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.492
4g1wG1WMitogen-activated protein kinase 82.7.11.240.492
4gk2L66Ephrin type-A receptor 32.7.10.10.492
4yuqKS1Calmodulin-like domain protein kinase/0.492
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.491
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.490
3mdvCL6Cholesterol 24-hydroxylase/0.490
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.490
4riyADPEpidermal growth factor receptor2.7.10.10.490
4wkqIREEpidermal growth factor receptor2.7.10.10.490
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.489
1zeoC01Peroxisome proliferator-activated receptor gamma/0.489
2qoqANPEphrin type-A receptor 32.7.10.10.489
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.489
4nka2K7Fibroblast growth factor receptor 1/0.489
5e92ANPTGF-beta receptor type-22.7.11.300.489
2hog710Serine/threonine-protein kinase Chk12.7.11.10.488
4c4g7RODual specificity protein kinase TTK2.7.12.10.488
4hnf16WCasein kinase I isoform delta2.7.11.10.488
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.487
2vwz7X6Ephrin type-B receptor 42.7.10.10.486
3h86AP5Adenylate kinase/0.486
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.486
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.486
3t2zFADSulfide-quinone reductase/0.485
4dgnLU2Casein kinase II subunit alpha2.7.11.10.485
4jia1K3Tyrosine-protein kinase JAK2/0.485
5a3bAPRSIR2 family protein/0.485
1ipeNDPTropinone reductase 21.1.1.2360.484
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.484
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.484
2itzIREEpidermal growth factor receptor2.7.10.10.483
2vx17X8Ephrin type-B receptor 42.7.10.10.483
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.483
2xvdAS6Ephrin type-B receptor 42.7.10.10.483
3mpaSB2Mitogen-activated protein kinase 14/0.483
4c58824Cyclin-G-associated kinase2.7.11.10.483
4jbpYPHAurora kinase A2.7.11.10.483
4lfiGNPCasein kinase II subunit alpha2.7.11.10.483
1bdlIM1Gag-Pol polyprotein3.4.23.160.482
1di8DTQCyclin-dependent kinase 22.7.11.220.482
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.482
2pvnP63Casein kinase II subunit alpha2.7.11.10.482
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.482
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.482
3l8p0CEAngiopoietin-1 receptor2.7.10.10.482
4k33ACPFibroblast growth factor receptor 32.7.10.10.482
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.482
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.482
1dawANPCasein kinase II subunit alpha2.7.11.10.481
2zdu446Mitogen-activated protein kinase 102.7.11.240.481
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.481
3gc9B45Mitogen-activated protein kinase 112.7.11.240.481
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.481
4g2fC07Ephrin type-A receptor 32.7.10.10.481
2hk51BMTyrosine-protein kinase HCK2.7.10.20.480
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.480
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.480
5eowFAD6-hydroxynicotinate 3-monooxygenase1.14.13.1140.480
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.479
3s4qNK0Mitogen-activated protein kinase 14/0.479
3w2sW2REpidermal growth factor receptor2.7.10.10.479
4btjADPTau-tubulin kinase 12.7.11.10.479
4lrjANPUncharacterized protein/0.479
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.479
5cshATPCasein kinase II subunit alpha2.7.11.10.479
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.478
2xp2VGHALK tyrosine kinase receptor2.7.10.10.478
5drdATPAurora kinase A2.7.11.10.478
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.477
2xa4AZ5Tyrosine-protein kinase JAK2/0.477
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.477
3igoANPCalmodulin-domain protein kinase 1, putative/0.477
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.476
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.476
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.476
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.476
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.476
4kl9NDPDihydrofolate reductase1.5.1.30.476
2izrBRKCasein kinase I isoform gamma-32.7.11.10.475
3at4CCKCasein kinase II subunit alpha2.7.11.10.475
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.475
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.475
4c57FEFCyclin-G-associated kinase2.7.11.10.475
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.475
5a3cNADSIR2 family protein/0.475
2iw84SPCyclin-dependent kinase 22.7.11.220.474
2py3ACPFibroblast growth factor receptor 2/0.474
2q9fC3SCholesterol 24-hydroxylase/0.474
2vd5BI8Myotonin-protein kinase2.7.11.10.474
3be9P04Casein kinase II subunit alpha2.7.11.10.474
3gwfFADCyclohexanone monooxygenase/0.474
3u9eCOALmo1369 protein/0.474
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.474
4nfn2KCTau-tubulin kinase 12.7.11.10.474
4y93746Tyrosine-protein kinase/0.474
2qocANPEphrin type-A receptor 32.7.10.10.473
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.473
4c4iX20Dual specificity protein kinase TTK2.7.12.10.473
4hys1BJMitogen-activated protein kinase 82.7.11.240.473
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.473
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.472
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.472
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.472
2itnANPEpidermal growth factor receptor2.7.10.10.472
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.472
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.472
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.472
3kpkFADSulfide-quinone reductase/0.472
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.472
3t2kFADSulfide-quinone reductase/0.472
3vs3VSETyrosine-protein kinase HCK2.7.10.20.472
4fv9E71Mitogen-activated protein kinase 12.7.11.240.472
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.472
5auwQUEDeath-associated protein kinase 12.7.11.10.472
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.471
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.471
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.471
2y6o1N1Ephrin type-A receptor 42.7.10.10.471
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.471
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.471
4jkt04AGlutaminase kidney isoform, mitochondrial3.5.1.20.471
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.471
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.470
3bgbLJGGag-Pol polyprotein3.4.23.160.470
3h0sB38Acetyl-CoA carboxylase/0.470
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.470
3uo50BXAurora kinase A2.7.11.10.470
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.470
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.470
4jboWPHAurora kinase A2.7.11.10.470
4oauADP2-5A-dependent ribonuclease3.1.260.470
4utdACPAurora kinase A2.7.11.10.470
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.470
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
2dwbANPAurora kinase A2.7.11.10.469
2vwy7X5Ephrin type-B receptor 42.7.10.10.469
2wotZZGTGF-beta receptor type-12.7.11.300.469
2wqeADPAurora kinase A2.7.11.10.469
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
3qwbNDPProbable quinone oxidoreductase1.6.5.50.469
3uyt0CKCasein kinase I isoform delta2.7.11.10.469
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.469
4hvh19RTyrosine-protein kinase JAK32.7.10.20.469
5dp2NAPCurF/0.469
1hiiC20Gag-Pol polyprotein/0.468
1nytNAPShikimate dehydrogenase (NADP(+))/0.468
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.468
2np8CC3Aurora kinase A2.7.11.10.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
3bw4FMNPutative 2-nitropropane dioxygenase/0.468
3d84NDPDihydrofolate reductase1.5.1.30.468
3efwAK8Aurora kinase A2.7.11.10.468
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.468
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.468
4elf35IDihydrofolate reductase/0.468
4eok4SPCyclin-dependent kinase 22.7.11.220.468
4fod0UVALK tyrosine kinase receptor2.7.10.10.468
4qmzB49Serine/threonine-protein kinase 242.7.11.10.468
2eq9FADDihydrolipoyl dehydrogenase/0.467
3ekv478Gag-Pol polyprotein3.4.23.160.467
4btmF8ETau-tubulin kinase 12.7.11.10.467
4kbk1QGCasein kinase I isoform delta2.7.11.10.467
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.467
4q73FADBifunctional protein PutA/0.467
4yryFADGlutamate synthase, beta subunit/0.467
1m2qMNXCasein kinase II subunit alpha2.7.11.10.466
2obyNAPQuinone oxidoreductase PIG310.466
2pwlACPFibroblast growth factor receptor 2/0.466
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
2xs0ANPMitogen-activated protein kinase 82.7.11.240.466
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
3oriAGSSerine/threonine protein kinase/0.466
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4eh60ONMitogen-activated protein kinase 14/0.466
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.466
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.466
4gub0Y4Casein kinase II subunit alpha2.7.11.10.466
1m2rMNYCasein kinase II subunit alpha2.7.11.10.465
1uyrD1LAcetyl-CoA carboxylase/0.465
1x2hLPALipoate-protein ligase A6.3.1.200.465
1xjdSTUProtein kinase C theta type2.7.11.130.465
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.465
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.465
2i0aMUIProtease/0.465
2of4979Tyrosine-protein kinase Lck2.7.10.20.465
3syiFADSulfide-quinone reductase/0.465
3v3vMYUMitogen-activated protein kinase 82.7.11.240.465
3vryB43Tyrosine-protein kinase HCK2.7.10.20.465
4anqVGHALK tyrosine kinase receptor2.7.10.10.465
4btkDTQTau-tubulin kinase 12.7.11.10.465
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.465
4izy1J2Mitogen-activated protein kinase 82.7.11.240.465
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.465
1e9hINRCyclin-dependent kinase 22.7.11.220.464
1fm9570Peroxisome proliferator-activated receptor gamma/0.464
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.464
1rw8580TGF-beta receptor type-12.7.11.300.464
1xefATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.464
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.464
2zgzGNPPlasmid segregation protein ParM/0.464
3at3ATKCasein kinase II subunit alpha2.7.11.10.464
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.464
3uvqFS8Mitogen-activated protein kinase 14/0.464
4dgmAGICasein kinase II subunit alpha2.7.11.10.464
4oavACP2-5A-dependent ribonuclease3.1.260.464
4yekTHMThymidine phosphorylase/0.464
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.463
2j0m4STFocal adhesion kinase 12.7.10.20.463
3kf7L9GMitogen-activated protein kinase 14/0.463
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.463
4dgo0JWCasein kinase II subunit alpha2.7.11.10.463
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.463
4hwkNAPSepiapterin reductase1.1.1.1530.463
4nks2M2Fibroblast growth factor receptor 1/0.463
5dt3ATPAurora kinase A2.7.11.10.463
1ouk084Mitogen-activated protein kinase 14/0.462
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.462
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.462
2j0k4STFocal adhesion kinase 12.7.10.20.462
2pym1UNGag-Pol polyprotein3.4.23.160.462
2wesFADTryptophan 5-halogenase/0.462
2x1nX1NCyclin-dependent kinase 22.7.11.220.462
3dxmN24Actin-related protein 3/0.462
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.462
3zuxTCHTransporter/0.462
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4kba1QMCasein kinase I isoform delta2.7.11.10.462
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.461
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.461
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.461
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.461
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.461
3flsFLSMitogen-activated protein kinase 14/0.461
3vt7VDXVitamin D3 receptor/0.461
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.461
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.461
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.461
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4hjoAQ4Epidermal growth factor receptor2.7.10.10.461
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.461
4ryvZEAProtein LlR18A/0.461
1jioDEB6-deoxyerythronolide B hydroxylase/0.460
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.460
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.460
2dcnADP2-keto-3-deoxy-gluconate kinase/0.460
2gjnFMNNitronate monooxygenase1.13.12.160.460
2ijmATPFocal adhesion kinase 12.7.10.20.460
2pvyACPFibroblast growth factor receptor 2/0.460
2vx07X7Ephrin type-B receptor 42.7.10.10.460
2xikJ60Serine/threonine-protein kinase 252.7.11.10.460
2znq401Peroxisome proliferator-activated receptor delta/0.460
3b6zCO7Enoyl reductase LovC10.460
3hx4ANPCalmodulin-domain protein kinase 1/0.460
3rk507ZCyclin-dependent kinase 22.7.11.220.460
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.460
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.460
4o0uADNAurora kinase A2.7.11.10.460
4q71FADBifunctional protein PutA/0.460
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.460
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.459
1cdeGARPhosphoribosylglycinamide formyltransferase/0.459
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.459
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1om1IQACasein kinase II subunit alpha2.7.11.10.459
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.459
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.459
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.459
2yfxVGHALK tyrosine kinase receptor2.7.10.10.459
3copADPGlycogen synthase2.4.1.210.459
3hllI45Mitogen-activated protein kinase 14/0.459
3pgqGY3Acetyl-CoA carboxylase/0.459
3ukuC69Actin-related protein 3/0.459
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.459
4a1zADPKinesin-like protein KIF11/0.459
4fkr45KCyclin-dependent kinase 22.7.11.220.459
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.459
1m2pHNACasein kinase II subunit alpha2.7.11.10.458
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.458
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2bmbPMMFolic acid synthesis protein FOL1/0.458
2ittAEEEpidermal growth factor receptor2.7.10.10.458
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.458
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.458
2yn8STUEphrin type-B receptor 42.7.10.10.458
3ddpRC8Cyclin-dependent kinase 22.7.11.220.458
3nu3478Gag-Pol polyprotein3.4.23.160.458
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.458
3sp9IL2Peroxisome proliferator-activated receptor delta/0.458
3t14FADSulfide-quinone reductase/0.458
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.458
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.458
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
4grb0XGCasein kinase II subunit alpha2.7.11.10.458
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.458
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.458
4u8pFDAUDP-galactopyranose mutase/0.458
4xumIMNPeroxisome proliferator-activated receptor gamma/0.458
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1mjbACOHistone acetyltransferase ESA1/0.457
1v9aSAHUncharacterized protein/0.457
1y4lSVRBasic phospholipase A2 homolog 2/0.457
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.457
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.457
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.457
2pvhP19Casein kinase II subunit alpha2.7.11.10.457
2wedPP6Penicillopepsin-13.4.23.200.457
3ddqRRCCyclin-dependent kinase 22.7.11.220.457
3hmm855TGF-beta receptor type-12.7.11.300.457
3q9xEMOCasein kinase II subunit alpha2.7.11.10.457
4gk3L87Ephrin type-A receptor 32.7.10.10.457
4ki8ADP60 kDa chaperonin/0.457
5cu6ATPCasein kinase II subunit alpha2.7.11.10.457
5ijzNAPNADP-specific glutamate dehydrogenase1.4.1.40.457
4z34ON7Lysophosphatidic acid receptor 1/0.457
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.456
1k6tXN1Gag-Pol polyprotein3.4.23.160.456
1ojtFADDihydrolipoyl dehydrogenase/0.456
2ath3EAPeroxisome proliferator-activated receptor gamma/0.456
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.456
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.456
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.456
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
3oxxDR7Gag-Pol polyprotein3.4.23.160.456
3zewSTUEphrin type-B receptor 42.7.10.10.456
4bb432WEphrin type-B receptor 42.7.10.10.456
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.456
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.456
4fob0USALK tyrosine kinase receptor2.7.10.10.456
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.456
4xiwAZMCarbonic anhydrase, alpha type/0.456
5dr6SKEAurora kinase A2.7.11.10.456
1eh4IC1Casein kinase I homolog 12.7.11.10.455
1jolFFODihydrofolate reductase1.5.1.30.455
1lp4ANPCasein kinase II subunit alpha2.7.11.10.455
2izsBRQCasein kinase I isoform gamma-32.7.11.10.455
2x9dITCTetracycline repressor protein class D/0.455
3fl8RARDihydrofolate reductase/0.455
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.455
3kfs3TLGag-Pol polyprotein/0.455
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.455
3vrwYS5Vitamin D3 receptor/0.455
4eevL1XHepatocyte growth factor receptor2.7.10.10.455
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.455
4lopSB4Mitogen-activated protein kinase 14/0.455
4q72FADBifunctional protein PutA/0.455
4qmpDKISerine/threonine-protein kinase 242.7.11.10.455
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.455
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
1rkxNADCDP-D-glucose-4,6-dehydratase/0.454
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.454
1yw2PGJMitogen-activated protein kinase 14/0.454
1zrzBI1Protein kinase C iota type2.7.11.130.454
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.454
2g8yNADHydroxycarboxylate dehydrogenase B/0.454
2nq8ZIDEnoyl-ACP reductase/0.454
2om9AJAPeroxisome proliferator-activated receptor gamma/0.454
2q61SF1Peroxisome proliferator-activated receptor gamma/0.454
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.454
2wouZZFTGF-beta receptor type-12.7.11.300.454
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.454
3vs1VSATyrosine-protein kinase HCK2.7.10.20.454
3wfjNAD2-dehydropantoate 2-reductase/0.454
4a28ADPKinesin-like protein KIF11/0.454
4a6cQG9Gag-Pol polyprotein3.4.23.160.454
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4c62XWWTyrosine-protein kinase JAK2/0.454
4cd2FOLDihydrofolate reductase1.5.1.30.454
4eol1ROCyclin-dependent kinase 22.7.11.220.454
4jr7GNPCasein kinase II subunit alpha2.7.11.10.454
4nbwNADShort-chain dehydrogenase/reductase SDR/0.454
5ap57RODual specificity protein kinase TTK2.7.12.10.454
5uviZMAAdenosine receptor A2a/0.454
1d4lPI9Gag-Pol polyprotein3.4.23.160.453
1hihC20Gag-Pol polyprotein/0.453
1ho5ADNProtein UshA3.1.3.50.453
1idb0DOGag-Pol polyprotein/0.453
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.453
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.453
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.453
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.453
2c6eHPMAurora kinase A2.7.11.10.453
2fy4COACholine O-acetyltransferase2.3.1.60.453
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
2hs2017Protease/0.453
2j0j4STFocal adhesion kinase 12.7.10.20.453
2qo7ANPEphrin type-A receptor 32.7.10.10.453
2wdzNADGalactitol dehydrogenase/0.453
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.453
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.453
3axwTIDCasein kinase II subunit alpha2.7.11.10.453
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.453
3hazFADBifunctional protein PutA/0.453
3nwxKVSGag-Pol polyprotein3.4.23.160.453
3qx2X63Cyclin-dependent kinase 22.7.11.220.453
3r9hZ67Cyclin-dependent kinase 22.7.11.220.453
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.453
3tucFPWTyrosine-protein kinase SYK2.7.10.20.453
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.453
4zrnUPGUDP-glucose 4-epimerase, putative/0.453
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.452
1oiyN41Cyclin-dependent kinase 22.7.11.220.452
1ol7ADPAurora kinase A2.7.11.10.452
1rx8NAPDihydrofolate reductase1.5.1.30.452
2a0cCK9Cyclin-dependent kinase 22.7.11.220.452
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2dvlFADAcyl-CoA dehydrogenase/0.452
2itvANPEpidermal growth factor receptor2.7.10.10.452
2xx91NFGlutamate receptor 2/0.452
2xyuQ9GEphrin type-A receptor 42.7.10.10.452
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.452
3dcrKVSProtease/0.452
3djkG55Gag-Pol polyprotein3.4.23.160.452
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.452
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3sdi3SDProteasome subunit beta type-53.4.25.10.452
3sdi3SDProteasome subunit beta type-63.4.25.10.452
3sz0FADSulfide-quinone reductase/0.452
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.452
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.452
4elg52JDihydrofolate reductase/0.452
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.452
4hvi19STyrosine-protein kinase JAK32.7.10.20.452
4iarERM5-hydroxytryptamine receptor 1B/0.452
4tuvCPZCytochrome P450 1191.140.452
4ye3G04Gag-Pol polyprotein3.4.23.160.452
1aq1STUCyclin-dependent kinase 22.7.11.220.451
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1dayGNPCasein kinase II subunit alpha2.7.11.10.451
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1f4fTP3Thymidylate synthase/0.451
1k6cMK1Gag-Pol polyprotein3.4.23.160.451
1pjkANPCasein kinase II subunit alpha2.7.11.10.451
1pkdUCNCyclin-dependent kinase 22.7.11.220.451
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.451
1pxmCK5Cyclin-dependent kinase 22.7.11.220.451
1udaUFGUDP-glucose 4-epimerase5.1.3.20.451
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.451
2cciATPCyclin-dependent kinase 22.7.11.220.451
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.451
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.451
2qhyMZ1Gag-Pol polyprotein/0.451
2qk8MTXDihydrofolate reductase/0.451
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.451
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.451
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.451
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.451
3ormAGSSerine/threonine protein kinase/0.451
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.451
3s2pPMUCyclin-dependent kinase 22.7.11.220.451
3umw596Serine/threonine-protein kinase pim-12.7.11.10.451
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.451
3w16P9JAurora kinase A2.7.11.10.451
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.451
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4gk4L90Ephrin type-A receptor 32.7.10.10.451
4hnc0UTMandelate racemase/0.451
4ic7ANPMitogen-activated protein kinase 72.7.11.240.451
4jbiNDPAlcohol dehydrogenase (Zinc)/0.451
4kb81QNCasein kinase I isoform delta2.7.11.10.451
4mwhATPCasein kinase II subunit alpha2.7.11.10.451
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
1osvCHCBile acid receptor/0.450
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.450
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
2aquDR7Gag-Pol polyprotein3.4.23.160.450
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.450
2igoFADPyranose 2-oxidase/0.450
2j4z626Aurora kinase A2.7.11.10.450
2pvlP55Casein kinase II subunit alpha2.7.11.10.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3bvb017Gag-Pol polyprotein3.4.23.160.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3em6017Gag-Pol polyprotein3.4.23.160.450
3ezrEZRCyclin-dependent kinase 22.7.11.220.450
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.450
3uzp0CKCasein kinase I isoform delta2.7.11.10.450
3zuyTCHTransporter/0.450
4g170VNCasein kinase I isoform gamma-32.7.11.10.450
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.450
4hge15VTyrosine-protein kinase JAK2/0.450
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.450
4tyj0LIFibroblast growth factor receptor 42.7.10.10.450
4xgiNADGlutamate dehydrogenase/0.450
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.449
1ec3MS3Gag-Pol polyprotein3.4.23.160.449
1gheACOAcetyltransferase2.3.10.449
1i44ACPInsulin receptor2.7.10.10.449
1t3r017Gag-Pol polyprotein3.4.23.160.449
1xl5190Gag-Pol polyprotein3.4.23.160.449
2ejvNADL-threonine 3-dehydrogenase/0.449
2fdd385Pol protein/0.449
2ignFADPyranose 2-oxidase/0.449
2iw94SPCyclin-dependent kinase 22.7.11.220.449
2q5g1FAPeroxisome proliferator-activated receptor delta/0.449
2qa1FADPgaE/0.449
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.449
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.449
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.449
3du8553Glycogen synthase kinase-3 beta2.7.11.260.449
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.449
3gggNADPrephenate dehydrogenase/0.449
3mtfA3FActivin receptor type-12.7.11.300.449
3qyw6PBMitogen-activated protein kinase 12.7.11.240.449
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ele31IDihydrofolate reductase/0.449
4enhFVXCholesterol 24-hydroxylase/0.449
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.449
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.449
4hni16WCasein kinase I isoform epsilon2.7.11.10.449
4l9kEHFSerum albumin/0.449
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.449
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
5dn3ATPAurora kinase A2.7.11.10.449
5dosATPAurora kinase A2.7.11.10.449
1c6yMK1Protease/0.448
1d4hBEHGag-Pol polyprotein3.4.23.160.448
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1fmjRTLRetinol dehydratase/0.448
1fwkADPHomoserine kinase2.7.1.390.448
1ppjANYCytochrome b/0.448
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.448
2bqvA1AProtease/0.448
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.448
2j5xGSPADP-ribosylation factor 6/0.448
2pz5ACPFibroblast growth factor receptor 2/0.448
2qnqQN3Gag-Pol polyprotein3.4.23.160.448
2w06FRVCyclin-dependent kinase 22.7.11.220.448
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.448
3d8bADPFidgetin-like protein 13.6.40.448
3gstGPRGlutathione S-transferase Mu 12.5.1.180.448
3l9hEMQKinesin-like protein KIF11/0.448
3s7a684Dihydrofolate reductase1.5.1.30.448
3t1tGDPProbable gliding protein mglA/0.448
3t3c017Gag-Pol polyprotein3.4.23.160.448
3t8oATPRhodopsin kinase/0.448
4a99FADTetX family tetracycline inactivation enzyme/0.448
4anmWULCasein kinase II subunit alpha2.7.11.10.448
4dfrMTXDihydrofolate reductase1.5.1.30.448
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.448
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.448
4fkw62KCyclin-dependent kinase 22.7.11.220.448
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.448
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.448
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.448
4pkl1GHUncharacterized protein/0.448
1dhjMTXDihydrofolate reductase1.5.1.30.447
1e3wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
1fy7COAHistone acetyltransferase ESA1/0.447
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.447
1mjaCOAHistone acetyltransferase ESA1/0.447
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.447
1udcUFMUDP-glucose 4-epimerase5.1.3.20.447
2j0lANPFocal adhesion kinase 12.7.10.20.447
2ou2ACOHistone acetyltransferase KAT5/0.447
2qhcAB1Protease/0.447
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2znpK55Peroxisome proliferator-activated receptor delta/0.447
3b7dCNIGlutamate receptor 2/0.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3lgxATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.447
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3slkNDPPolyketide synthase extender module 2/0.447
3sm2478Putative gag-pro-pol polyprotein/0.447
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.447
3ufnROCGag-Pol polyprotein/0.447
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.447
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.447
3zh8C58Protein kinase C iota type2.7.11.130.447
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4ansVGHALK tyrosine kinase receptor2.7.10.10.447
4b99R4LMitogen-activated protein kinase 72.7.11.240.447
4bcmT7ZCyclin-dependent kinase 22.7.11.220.447
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.447
4btjATPTau-tubulin kinase 12.7.11.10.447
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.447
4j7xNAPSepiapterin reductase1.1.1.1530.447
4loqSB4Mitogen-activated protein kinase 14/0.447
4nb6444Nuclear receptor ROR-gamma/0.447
5ap7SVEDual specificity protein kinase TTK2.7.12.10.447
5cvfATPCasein kinase II subunit alpha2.7.11.10.447
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.446
1bw9NADPhenylalanine dehydrogenase/0.446
1ia4TQ6Dihydrofolate reductase1.5.1.30.446
1jld0PPGag-Pol polyprotein/0.446
1xe55FEPlasmepsin-23.4.23.390.446
2jb4A14Isopenicillin N synthase1.21.3.10.446
2nomDUTPoly(A) polymerase, putative/0.446
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.446
3icsADPCoenzyme A disulfide reductase/0.446
3jynNDPQuinone oxidoreductase/0.446
3o8tBMUMitogen-activated protein kinase 14/0.446
3oroAGSSerine/threonine protein kinase/0.446
3oxv478Gag-Pol polyprotein3.4.23.160.446
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3qzhX69Cyclin-dependent kinase 22.7.11.220.446
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.446
3zsi52PMitogen-activated protein kinase 14/0.446
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4dqf017Gag-Pol polyprotein/0.446
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.446
4fkq42KCyclin-dependent kinase 22.7.11.220.446
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.446
4j7uNAPSepiapterin reductase1.1.1.1530.446
4njt017Protease/0.446
4ure1PSCyclohexanol dehydrogenase/0.446
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.446
5k2bZMAAdenosine receptor A2a/0.446
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1ebzBECGag-Pol polyprotein3.4.23.160.445
1eioGCHGastrotropin/0.445
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.445
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1tcxIM1Gag-Pol polyprotein3.4.23.160.445
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.445
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.445
2qa2FADPolyketide oxygenase CabE/0.445
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.445
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2zmd537Dual specificity protein kinase TTK2.7.12.10.445
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.445
3r9dX6BCyclin-dependent kinase 22.7.11.220.445
3uxyNADShort-chain dehydrogenase/reductase SDR/0.445
3wmxNADNAD dependent epimerase/dehydratase/0.445
3zptM8YGag-Pol polyprotein3.4.23.160.445
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.445
4b7xNAPProbable oxidoreductase/0.445
4c3rACPAurora kinase A2.7.11.10.445
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.445
4iva1J5Tyrosine-protein kinase JAK2/0.445
4j54G52Gag-Pol polyprotein3.4.23.160.445
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.445
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.444
1h0w207Cyclin-dependent kinase 22.7.11.220.444
1h1s4SPCyclin-dependent kinase 22.7.11.220.444
1oiuN76Cyclin-dependent kinase 22.7.11.220.444
1rdt570Peroxisome proliferator-activated receptor gamma/0.444
1ykdCMPAdenylate cyclase/0.444
1zdwFLVPrenyltransferase/0.444
2bhhRYUCyclin-dependent kinase 22.7.11.220.444
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.444
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.444
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.444
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.444
2qnpQN2Gag-Pol polyprotein3.4.23.160.444
2uy0HV1Gag-Pol polyprotein3.4.23.160.444
2vwu7X1Ephrin type-B receptor 42.7.10.10.444
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.444
3bgcLJHGag-Pol polyprotein3.4.23.160.444
3icrCOACoenzyme A disulfide reductase/0.444
3il1B5DGlutamate receptor 2/0.444
3kxw1ZZSaframycin Mx1 synthetase B/0.444
3l0lHC3Nuclear receptor ROR-gamma/0.444
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3nwq2NCGag-Pol polyprotein3.4.23.160.444
3s1dZIRCytokinin dehydrogenase 11.5.99.120.444
3t2yFADSulfide-quinone reductase/0.444
3zxtACPDeath-associated protein kinase 12.7.11.10.444
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
4a6bQG8Gag-Pol polyprotein3.4.23.160.444
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.444
4eos1ROCyclin-dependent kinase 22.7.11.220.444
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.444
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.444
4fuxE75Mitogen-activated protein kinase 12.7.11.240.444
4h0xNADIota toxin component Ia/0.444
4iaq2GM5-hydroxytryptamine receptor 1B/0.444
4jrvKJVEpidermal growth factor receptor2.7.10.10.444
4nr42LKCREB-binding protein/0.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
4wboANWRhodopsin kinase/0.444
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.444
5k2dZMAAdenosine receptor A2a/0.444
1ci7UMPThymidylate synthase2.1.1.450.443
1diuBDMDihydrofolate reductase1.5.1.30.443
1ewyFADFerredoxin--NADP reductase1.18.1.20.443
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1jipKTN6-deoxyerythronolide B hydroxylase/0.443
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.443
1ml6GBXGlutathione S-transferase A22.5.1.180.443
1muiAB1Protease/0.443
1xelUPGUDP-glucose 4-epimerase5.1.3.20.443
2o7oDXTTetracycline repressor protein class D/0.443
2ok7FADFerredoxin--NADP reductase, apicoplast/0.443
2q641UNGag-Pol polyprotein3.4.23.160.443
2qnnQN1Gag-Pol polyprotein3.4.23.160.443
2w1fL0FAurora kinase A2.7.11.10.443
2w1gL0GAurora kinase A2.7.11.10.443
2y4gTIRTamL/0.443
3bi6396Wee1-like protein kinase2.7.10.20.443
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
3ielU5PRibonuclease TTHA02523.10.443
3kb1ADPIron-sulfur cluster carrier protein/0.443
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.443
3nu5478Gag-Pol polyprotein3.4.23.160.443
3q9zTXQCasein kinase II subunit alpha2.7.11.10.443
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.443
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4f640S8Fibroblast growth factor receptor 1/0.443
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.443
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.443
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.443
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.443
4gh5NADShort-chain dehydrogenase/reductase SDR/0.443
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.443
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.443
5bsfNADPyrroline-5-carboxylate reductase/0.443
5eccNAPDehydrofolate reductase type I/0.443
1ebwBEIGag-Pol polyprotein3.4.23.160.442
1mq4ADPAurora kinase A2.7.11.10.442
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.442
1sh9RITGag-Pol polyprotein3.4.23.160.442
1xkkFMMEpidermal growth factor receptor2.7.10.10.442
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.442
2du8FADD-amino-acid oxidase1.4.3.30.442
2eixFADNADH-cytochrome b5 reductase/0.442
2in6839Wee1-like protein kinase2.7.10.20.442
2pzpACPFibroblast growth factor receptor 2/0.442
2qboCAMCamphor 5-monooxygenase1.14.15.10.442
2uzlC94Cyclin-dependent kinase 22.7.11.220.442
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.442
3ac1KZITyrosine-protein kinase Lck2.7.10.20.442
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.442
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.442
3jvwDMPGag-Pol polyprotein3.4.23.160.442
3mdmFJZCholesterol 24-hydroxylase/0.442
3mvl38PMitogen-activated protein kinase 14/0.442
3oxw017Gag-Pol polyprotein3.4.23.160.442
3tqhNDPQuinone oxidoreductase/0.442
3zksWZVBeta-secretase 23.4.23.450.442
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.442
4a6nFADTetX family tetracycline inactivation enzyme/0.442
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4iskUMPThymidylate synthase/0.442
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1bwfATFGlycerol kinase/0.441
1e1mFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.441
1hvrXK2Gag-Pol polyprotein/0.441
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.441
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
1kzjCB3Thymidylate synthase/0.441
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.441
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.441
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2bakAQZMitogen-activated protein kinase 14/0.441
2w17I19Cyclin-dependent kinase 22.7.11.220.441
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.441
2wsbNADGalactitol dehydrogenase/0.441
2xh9J01Uncharacterized protein/0.441
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.441
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.441
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.441
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.441
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.441
3rm618ZCyclin-dependent kinase 22.7.11.220.441
3rmf20ZCyclin-dependent kinase 22.7.11.220.441
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.441
3ruqADPChaperonin/0.441
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.441
3vthAPCCarbamoyltransferase/0.441
4a9yAQZMitogen-activated protein kinase 14/0.441
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.441
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.441
4cd0AWJALK tyrosine kinase receptor2.7.10.10.441
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.441
4dshFDAUncharacterized protein/0.441
4eh70OOMitogen-activated protein kinase 14/0.441
4emaBRLPeroxisome proliferator-activated receptor gamma/0.441
4kwi1TJReductase homolog/0.441
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.441
4qgiROCGag-Pol polyprotein3.4.23.160.441
5dt4ATPAurora kinase A2.7.11.10.441
5hwsNAP2-dehydropantoate 2-reductase/0.441
1hosPHPGag-Pol polyprotein/0.440
1jmfUMPThymidylate synthase/0.440
1k6pXN3Gag-Pol polyprotein3.4.23.160.440
1knuYPAPeroxisome proliferator-activated receptor gamma/0.440
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.440
1mrwK57Gag-Pol polyprotein3.4.23.160.440
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.440
1rj6AZMCarbonic anhydrase 144.2.1.10.440
1sduMK1Gag-Pol polyprotein3.4.23.160.440
1tdrMTXDihydrofolate reductase1.5.1.30.440
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.440
1wbmBLLPol protein/0.440
1x8b824Wee1-like protein kinase2.7.10.20.440
1yb5NAPQuinone oxidoreductase1.6.5.50.440
1zyjBI5Mitogen-activated protein kinase 14/0.440
2bfyH1NAurora kinase B-A2.7.11.10.440
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.440
2c7xNRBCytochrome P450 monooxygenase PikC/0.440
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
2gtmLIDMitogen-activated protein kinase 14/0.440
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.440
2rhrEMOPutative ketoacyl reductase1.3.10.440
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.440
2x7hPFNProstaglandin reductase 310.440
2xru400Aurora kinase A2.7.11.10.440
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.440
3cgcFADCoenzyme A disulfide reductase/0.440
3d3wNAPL-xylulose reductase1.1.1.100.440
3dxjNE6DNA-directed RNA polymerase subunit beta/0.440
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.440
3eej53RUncharacterized protein/0.440
3enkUPGUDP-glucose 4-epimerase/0.440
3fc152PMitogen-activated protein kinase 14/0.440
3fmjFMJMitogen-activated protein kinase 14/0.440
3gobHXXDdmC/0.440
3i7eDJRGag-Pol polyprotein/0.440
3jw3TOPDihydrofolate reductase/0.440
3kfn3TLGag-Pol polyprotein/0.440
3lfnA27Cyclin-dependent kinase 22.7.11.220.440
3nga3NGCasein kinase II subunit alpha2.7.11.10.440
3nu4478Gag-Pol polyprotein3.4.23.160.440
3o9dK19Pol polyprotein/0.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
3r9uFADThioredoxin reductase/0.440
3sa323XProtease/0.440
3sheI85MAP kinase-activated protein kinase 32.7.11.10.440
3uvp048Mitogen-activated protein kinase 14/0.440
3v9v21LPeroxisome proliferator-activated receptor gamma/0.440
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
4em9TCEPeroxisome proliferator-activated receptor gamma/0.440
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.440
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.440
4g3jVNTLanosterol 14-alpha-demethylase/0.440
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4jajXU1Aurora kinase A2.7.11.10.440
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.440
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.440
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
5dr2ATPAurora kinase A2.7.11.10.440
5f8eSAHPossible transcriptional regulatory protein/0.440