sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2esd	NAP	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	1.2.1.9

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2esd	NAP	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	1.2.1.9	1.000
3rhh	NAP	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	/	0.564
3rhd	NAP	Lactaldehyde dehydrogenase	1.2.1.22	0.490
2jg7	NAD	Antiquitin	/	0.453
3ju8	NAD	N-succinylglutamate 5-semialdehyde dehydrogenase	1.2.1.71	0.450
2j6l	NAI	Alpha-aminoadipic semialdehyde dehydrogenase	1.2.1.31	0.447
5eyu	NAD	Betaine-aldehyde dehydrogenase	/	0.445
4i3v	NAD	Aldehyde dehydrogenase (NAD+)	/	0.443