sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eh2 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2eh2 | SAH | Diphthine synthase | / | 1.000 | |
| 2owk | SAH | Diphthine synthase | / | 0.855 | |
| 2ehl | SAH | Diphthine synthase | / | 0.834 | |
| 2hut | SAH | Diphthine synthase | / | 0.809 | |
| 2ele | SAH | Diphthine synthase | / | 0.803 | |
| 2e8r | SAH | Diphthine synthase | / | 0.788 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.767 | |
| 2p5f | SAH | Diphthine synthase | / | 0.766 | |
| 2emr | SAH | Diphthine synthase | / | 0.765 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.764 | |
| 2emu | SAH | Diphthine synthase | / | 0.762 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.757 | |
| 2p6d | SAH | Diphthine synthase | / | 0.747 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.735 | |
| 2owg | SAH | Diphthine synthase | / | 0.731 | |
| 2eni | SAH | Diphthine synthase | / | 0.728 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.722 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.722 | |
| 2e17 | SAH | Diphthine synthase | / | 0.719 | |
| 2p5c | SAH | Diphthine synthase | / | 0.718 | |
| 2p2x | SAH | Diphthine synthase | / | 0.713 | |
| 2dxv | SAH | Diphthine synthase | / | 0.709 | |
| 2dxw | SAH | Diphthine synthase | / | 0.709 | |
| 2dsi | SAH | Diphthine synthase | / | 0.708 | |
| 2e8s | SAH | Diphthine synthase | / | 0.699 | |
| 2ejk | SAH | Diphthine synthase | / | 0.697 | |
| 2e15 | SAH | Diphthine synthase | / | 0.695 | |
| 2dsg | SAH | Diphthine synthase | / | 0.693 | |
| 2e7r | SAH | Diphthine synthase | / | 0.689 | |
| 2eka | SAH | Diphthine synthase | / | 0.689 | |
| 2pcg | SAH | Diphthine synthase | / | 0.688 | |
| 2e4n | SAH | Diphthine synthase | / | 0.685 | |
| 2huv | SAH | Diphthine synthase | / | 0.685 | |
| 2z6r | SAH | Diphthine synthase | / | 0.683 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.681 | |
| 2egs | SAH | Diphthine synthase | / | 0.677 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.675 | |
| 2pcm | SAH | Diphthine synthase | / | 0.673 | |
| 2el3 | SAH | Diphthine synthase | / | 0.672 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.666 | |
| 2dxx | SAH | Diphthine synthase | / | 0.665 | |
| 2el0 | SAH | Diphthine synthase | / | 0.661 | |
| 2owu | SAH | Diphthine synthase | / | 0.657 | |
| 2p6i | SAH | Diphthine synthase | / | 0.657 | |
| 2p6k | SAH | Diphthine synthase | / | 0.652 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.650 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.647 | |
| 1vce | SAH | Diphthine synthase | / | 0.646 | |
| 2eld | SAH | Diphthine synthase | / | 0.646 | |
| 2p9d | SAH | Diphthine synthase | / | 0.646 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.643 | |
| 2e16 | SAH | Diphthine synthase | / | 0.642 | |
| 2e8q | SAH | Diphthine synthase | / | 0.642 | |
| 2egb | SAH | Diphthine synthase | / | 0.641 | |
| 2dek | SAH | Diphthine synthase | / | 0.638 | |
| 2pci | SAH | Diphthine synthase | / | 0.637 | |
| 1wng | SAH | Diphthine synthase | / | 0.636 | |
| 2owv | SAH | Diphthine synthase | / | 0.634 | |
| 2eeq | SAH | Diphthine synthase | / | 0.630 | |
| 2en5 | SAH | Diphthine synthase | / | 0.629 | |
| 2pck | SAH | Diphthine synthase | / | 0.627 | |
| 2e8h | SAH | Diphthine synthase | / | 0.619 | |
| 2egl | SAH | Diphthine synthase | / | 0.615 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.614 | |
| 2huq | SAH | Diphthine synthase | / | 0.613 | |
| 2hux | SAH | Diphthine synthase | / | 0.608 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.604 | |
| 2e08 | SAH | Diphthine synthase | / | 0.597 | |
| 2pca | SAH | Diphthine synthase | / | 0.595 | |
| 2p6l | SAH | Diphthine synthase | / | 0.594 | |
| 2pch | SAH | Diphthine synthase | / | 0.591 | |
| 2owf | SAH | Diphthine synthase | / | 0.578 | |
| 2e07 | SAH | Diphthine synthase | / | 0.576 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.570 | |
| 2ejj | SAH | Diphthine synthase | / | 0.550 | |
| 2dsh | SAH | Diphthine synthase | / | 0.538 | |
| 2ejz | SAH | Diphthine synthase | / | 0.520 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.490 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.469 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.463 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.459 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.450 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3ieu | GDP | GTPase Era | / | 0.448 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.445 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.442 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.441 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.441 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.441 |