sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eg8 | FOT | Dihydroorotase | 3.5.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2eg8 | FOT | Dihydroorotase | 3.5.2.3 | 1.000 | |
| 4e2b | FMN | Dehydrogenase | / | 0.457 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.446 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.443 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.443 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.440 |