sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 | 1.000 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.513 | |
| 4weq | NAP | NAD-dependent dehydrogenase | / | 0.495 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.488 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.470 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.454 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.452 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.448 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.445 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.443 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.440 |