Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2d2gDZZPhosphotriesterase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2d2gDZZPhosphotriesterase/1.000
2r1nEPLPhosphotriesterase/0.739
1dpmEBPParathion hydrolase3.1.8.10.493
3q7fED2Uncharacterized protein/0.470
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.463
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
1ygjRMCPyridoxal kinase2.7.1.350.460
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.10.457
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.455
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.451
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.445
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.443
4bfyZVYPantothenate kinase2.7.1.330.443
5jdzSAHMethyl transferase/0.443
2gesCOKPantothenate kinase2.7.1.330.442
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.442
4d6qPD2Lysine-specific demethylase 4D1.14.110.442
1gky5GPGuanylate kinase2.7.4.80.440
1yhjR6CPyridoxal kinase2.7.1.350.440