sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cvq | NDP | Malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2cvq | NDP | Malate dehydrogenase | / | 1.000 | |
| 1y7t | NDP | Malate dehydrogenase | / | 0.639 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.568 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.561 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.557 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.531 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.528 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.516 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.516 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.495 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.480 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.450 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.449 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.444 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.441 |