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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.11.000
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.588
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.556
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.556
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.553
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.548
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.545
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.544
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.543
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.541
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.541
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.540
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.535
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.533
2hog710Serine/threonine-protein kinase Chk12.7.11.10.532
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.531
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.529
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.528
5av4GENDeath-associated protein kinase 12.7.11.10.527
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.525
5auwQUEDeath-associated protein kinase 12.7.11.10.524
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.523
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.522
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.521
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.520
1jkkANPDeath-associated protein kinase 12.7.11.10.518
3gu6ADPDeath-associated protein kinase 12.7.11.10.518
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.517
3c4xATPRhodopsin kinase/0.517
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.516
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.516
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.516
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.516
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.515
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.514
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.514
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.514
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.514
2ckeIQUDeath-associated protein kinase 2/0.513
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.512
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.512
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.512
4bcmT7ZCyclin-dependent kinase 22.7.11.220.511
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.510
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.509
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.509
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.509
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.508
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.507
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.507
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.507
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.507
1jklANPDeath-associated protein kinase 12.7.11.10.506
2w4jADPDeath-associated protein kinase 12.7.11.10.506
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.506
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.506
5av2KMPDeath-associated protein kinase 12.7.11.10.506
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.505
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.505
3t8oATPRhodopsin kinase/0.505
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.504
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.504
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.504
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.502
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.501
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.500
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.500
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.500
5auvAGIDeath-associated protein kinase 12.7.11.10.500
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.499
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.499
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.499
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.498
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.498
1finATPCyclin-dependent kinase 22.7.11.220.496
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.496
2j0lANPFocal adhesion kinase 12.7.10.20.496
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.495
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.495
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.495
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.494
3a62STURibosomal protein S6 kinase beta-12.7.11.10.494
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.493
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.493
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.493
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.492
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.492
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.492
4c57FEFCyclin-G-associated kinase2.7.11.10.492
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.491
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.491
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.491
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.490
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.490
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.490
3eb0DRKUncharacterized protein/0.490
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.490
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.490
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.490
5av047XDeath-associated protein kinase 12.7.11.10.490
1wvxBD4Death-associated protein kinase 12.7.11.10.489
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.489
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.489
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.489
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.489
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.488
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.488
3sheI85MAP kinase-activated protein kinase 32.7.11.10.488
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
5dt3ATPAurora kinase A2.7.11.10.488
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.487
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.487
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.487
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.487
4ic7ANPMitogen-activated protein kinase 72.7.11.240.487
1u54ACPActivated CDC42 kinase 1/0.486
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.486
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.486
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.485
2vgoAD5Aurora kinase B-A2.7.11.10.485
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.485
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.484
4gstGTDGlutathione S-transferase Mu 12.5.1.180.484
1fvv107Cyclin-dependent kinase 22.7.11.220.483
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.483
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.483
4j97ACPFibroblast growth factor receptor 2/0.483
4jia1K3Tyrosine-protein kinase JAK2/0.483
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.482
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.482
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.482
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.482
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.481
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.481
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.481
4gmy0X5Tyrosine-protein kinase JAK2/0.481
4k33ACPFibroblast growth factor receptor 32.7.10.10.481
4l9i8PRRhodopsin kinase/0.481
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.480
3at4CCKCasein kinase II subunit alpha2.7.11.10.480
3ggfGVDSerine/threonine-protein kinase 26/0.480
3gubGUBDeath-associated protein kinase 12.7.11.10.480
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.480
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.480
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3igoANPCalmodulin-domain protein kinase 1, putative/0.479
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.479
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.479
4o0wADNAurora kinase A2.7.11.10.479
4ysjADPCalmodulin-like domain protein kinase/0.479
5dnrATPAurora kinase A2.7.11.10.479
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.478
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.478
2ijmATPFocal adhesion kinase 12.7.10.20.478
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.478
3gu5ANPDeath-associated protein kinase 12.7.11.10.478
4i4e1BQFocal adhesion kinase 12.7.10.20.478
2uzbC75Cyclin-dependent kinase 22.7.11.220.477
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.477
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.477
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.477
4brxKGWFocal adhesion kinase 12.7.10.20.477
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.476
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.475
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.475
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.475
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.475
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.475
1pkdUCNCyclin-dependent kinase 22.7.11.220.474
1xjdSTUProtein kinase C theta type2.7.11.130.474
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.474
4btjATPTau-tubulin kinase 12.7.11.10.474
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.474
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.473
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.473
2vu3LZECyclin-dependent kinase 22.7.11.220.473
2w1fL0FAurora kinase A2.7.11.10.473
3a7hATPSerine/threonine-protein kinase 242.7.11.10.473
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.473
3nynSGVG protein-coupled receptor kinase 62.7.11.160.473
3w2sW2REpidermal growth factor receptor2.7.10.10.473
4eooATPCyclin-dependent kinase 22.7.11.220.473
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.473
5dr6SKEAurora kinase A2.7.11.10.473
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.472
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.472
2w17I19Cyclin-dependent kinase 22.7.11.220.472
2x9fX9FEphrin type-B receptor 42.7.10.10.472
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.472
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3nux3NVCyclin-dependent kinase 62.7.11.220.472
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.472
3dfcANPDeath-associated protein kinase 12.7.11.10.471
4bbfO19Tyrosine-protein kinase JAK2/0.471
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.471
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.471
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.471
5auxKMPDeath-associated protein kinase 12.7.11.10.471
5auzGENDeath-associated protein kinase 12.7.11.10.471
5e92ANPTGF-beta receptor type-22.7.11.300.471
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.470
4b8lA0PAurora kinase B-A2.7.11.10.470
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.470
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.470
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.470
1looGTPAdenylosuccinate synthetase isozyme 1/0.469
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.469
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.469
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.469
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.469
3eljGS7Mitogen-activated protein kinase 82.7.11.240.469
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.469
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.469
1zys199Serine/threonine-protein kinase Chk12.7.11.10.468
2eb3ANPEpidermal growth factor receptor2.7.10.10.468
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.468
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4b99R4LMitogen-activated protein kinase 72.7.11.240.468
4d58BI9Focal adhesion kinase 12.7.10.20.468
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4jbqVX6Aurora kinase A2.7.11.10.468
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.467
2vv9IM9Cyclin-dependent kinase 22.7.11.220.467
3zep1NXTyrosine-protein kinase JAK32.7.10.20.467
4cd0AWJALK tyrosine kinase receptor2.7.10.10.467
4eoi1ROCyclin-dependent kinase 22.7.11.220.467
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.466
3pxkPXKFocal adhesion kinase 12.7.10.20.466
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.466
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.466
4k8aK8AFocal adhesion kinase 12.7.10.20.466
5dr9SKEAurora kinase A2.7.11.10.466
5e8ySTUTGF-beta receptor type-22.7.11.300.466
2c5yMTWCyclin-dependent kinase 22.7.11.220.465
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.465
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.465
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.465
3zh8C58Protein kinase C iota type2.7.11.130.465
4ccbOFGALK tyrosine kinase receptor2.7.10.10.465
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.465
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.464
2xngA0HAurora kinase A2.7.11.10.464
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.464
3bhy7CPDeath-associated protein kinase 3/0.464
3c50ADPRhodopsin kinase/0.464
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.464
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.464
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.464
4d4sBI9Focal adhesion kinase 12.7.10.20.464
4iwd1JCHepatocyte growth factor receptor2.7.10.10.464
4jajXU1Aurora kinase A2.7.11.10.464
5dt0SKEAurora kinase A2.7.11.10.464
1dmpDMQGag-Pol polyprotein3.4.23.160.463
1oirHDYCyclin-dependent kinase 22.7.11.220.463
1pxpCK8Cyclin-dependent kinase 22.7.11.220.463
1wvySTUDeath-associated protein kinase 12.7.11.10.463
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.463
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.463
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.463
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.463
3nszANPCasein kinase II subunit alpha2.7.11.10.463
3qc9ADPRhodopsin kinase/0.463
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.463
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.463
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.463
4hge15VTyrosine-protein kinase JAK2/0.463
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.463
4n57ADPAPH(2'')-Id/0.463
1om1IQACasein kinase II subunit alpha2.7.11.10.462
2x4f16XMyosin light chain kinase family member 42.7.11.10.462
3c4zADPRhodopsin kinase/0.462
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.462
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.462
4hvi19STyrosine-protein kinase JAK32.7.10.20.462
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.462
5dosATPAurora kinase A2.7.11.10.462
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.461
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2xp2VGHALK tyrosine kinase receptor2.7.10.10.461
4dtaADNAPH(2'')-Id/0.461
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.461
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1pyePM1Cyclin-dependent kinase 22.7.11.220.460
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.460
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.460
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.460
3tnwF18Cyclin-dependent kinase 22.7.11.220.460
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.460
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.460
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.460
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.459
2pwlACPFibroblast growth factor receptor 2/0.459
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.459
3orkAGSSerine/threonine protein kinase/0.459
3vs3VSETyrosine-protein kinase HCK2.7.10.20.459
4fx360KCyclin-dependent kinase 22.7.11.220.459
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.459
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.459
5hi2BAXSerine/threonine-protein kinase B-raf2.7.11.10.459
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.458
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.458
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.458
2yaaATPDeath-associated protein kinase 2/0.458
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.458
4ix5ANPUncharacterized protein/0.458
4jrnANPRhoptry kinase family protein/0.458
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.457
4aguD15Cyclin-dependent kinase-like 1/0.457
4dgnLU2Casein kinase II subunit alpha2.7.11.10.457
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.457
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.457
4ix6ADPUncharacterized protein/0.457
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.457
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.456
2vgpAD6Aurora kinase B-A2.7.11.10.456
3t9aANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.456
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.456
4f640S8Fibroblast growth factor receptor 1/0.456
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fks46KCyclin-dependent kinase 22.7.11.220.456
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.456
1hk2T44Serum albumin/0.455
1m2rMNYCasein kinase II subunit alpha2.7.11.10.455
1w2xRCPAcetyl-CoA carboxylase/0.455
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.455
2btsU32Cyclin-dependent kinase 22.7.11.220.455
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.455
3hng8STVascular endothelial growth factor receptor 12.7.10.10.455
3i60E86Mitogen-activated protein kinase 12.7.11.240.455
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.455
3rak03ZCyclin-dependent kinase 22.7.11.220.455
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.455
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.455
5br7FADUDP-galactopyranose mutase/0.455
5eg3ACPFibroblast growth factor receptor 2/0.455
1k6tXN1Gag-Pol polyprotein3.4.23.160.454
1p2a5BNCyclin-dependent kinase 22.7.11.220.454
1u4dDBQActivated CDC42 kinase 1/0.454
2bmcMPYAurora kinase A2.7.11.10.454
2xuuADPDeath-associated protein kinase 12.7.11.10.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4foc0UUALK tyrosine kinase receptor2.7.10.10.454
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.454
4xlvACPInsulin receptor2.7.10.10.454
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.453
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.453
2pd8FADVivid PAS protein VVD/0.453
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3lltANPProtein serine/threonine kinase-1/0.453
3rmf20ZCyclin-dependent kinase 22.7.11.220.453
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.453
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.453
3zdu38RCyclin-dependent kinase-like 32.7.11.220.453
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.453
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.453
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.453
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.452
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.452
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.452
2itqITQEpidermal growth factor receptor2.7.10.10.452
2x1nX1NCyclin-dependent kinase 22.7.11.220.452
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.452
4fxfATPPyruvate kinase PKM2.7.1.400.452
4grb0XGCasein kinase II subunit alpha2.7.11.10.452
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.452
1ir3ANPInsulin receptor2.7.10.10.451
2p33J07Mitogen-activated protein kinase 102.7.11.240.451
3be9P04Casein kinase II subunit alpha2.7.11.10.451
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
3uvqFS8Mitogen-activated protein kinase 14/0.451
4ddhMS0Pantothenate synthetase6.3.2.10.451
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
1eioGCHGastrotropin/0.450
1py5PY1TGF-beta receptor type-12.7.11.300.450
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.450
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.450
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.450
2eufLQQCyclin-dependent kinase 62.7.11.220.450
2w1dL0DAurora kinase A2.7.11.10.450
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.450
3a8wATPProtein kinase C iota type2.7.11.130.450
3oom507Activin receptor type-12.7.11.300.450
3r1yX76Cyclin-dependent kinase 22.7.11.220.450
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.450
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.450
5aut2ANDeath-associated protein kinase 12.7.11.10.450
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2izuP01Casein kinase I isoform gamma-32.7.11.10.449
2w1gL0GAurora kinase A2.7.11.10.449
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
3qaiXNNKetohexokinase/0.449
3uzp0CKCasein kinase I isoform delta2.7.11.10.449
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.449
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.449
4btjADPTau-tubulin kinase 12.7.11.10.449
4fv6E57Mitogen-activated protein kinase 12.7.11.240.449
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.449
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
5dpvSKEAurora kinase A2.7.11.10.449
1kv1BMUMitogen-activated protein kinase 14/0.448
1pmv537Mitogen-activated protein kinase 102.7.11.240.448
1pxlCK4Cyclin-dependent kinase 22.7.11.220.448
1ykdCMPAdenylate cyclase/0.448
1yvj4STTyrosine-protein kinase JAK32.7.10.20.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2c4g514Cyclin-dependent kinase 22.7.11.220.448
2izsBRQCasein kinase I isoform gamma-32.7.11.10.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2y9qANPMitogen-activated protein kinase 12.7.11.240.448
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.448
3c4wATPRhodopsin kinase/0.448
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.448
3ekx1UNGag-Pol polyprotein3.4.23.160.448
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.448
3u4uLNHCasein kinase II subunit alpha2.7.11.10.448
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.448
3w16P9JAurora kinase A2.7.11.10.448
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.448
4bgg844Activin receptor type-12.7.11.300.448
4deaNHIAurora kinase A2.7.11.10.448
5dn3ATPAurora kinase A2.7.11.10.448
1eh4IC1Casein kinase I homolog 12.7.11.10.447
2etm7PYFocal adhesion kinase 12.7.10.20.447
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.447
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.447
3mb714ICasein kinase II subunit alpha2.7.11.10.447
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.447
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.447
4fob0USALK tyrosine kinase receptor2.7.10.10.447
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.447
4l49CAMCamphor 5-monooxygenase1.14.15.10.447
4lrjANPUncharacterized protein/0.447
5dt4ATPAurora kinase A2.7.11.10.447
1c70L75Protease/0.446
1j39UPGDNA beta-glucosyltransferase/0.446
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.446
1oecAA2Fibroblast growth factor receptor 2/0.446
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2csnCKICasein kinase I homolog 12.7.11.10.446
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.446
3nxe2NCProtease/0.446
3rk507ZCyclin-dependent kinase 22.7.11.220.446
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.446
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.446
4hvh19RTyrosine-protein kinase JAK32.7.10.20.446
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.446
4nka2K7Fibroblast growth factor receptor 1/0.446
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.445
1pxoCK7Cyclin-dependent kinase 22.7.11.220.445
2a1oCAMCamphor 5-monooxygenase1.14.15.10.445
2henADPEphrin type-B receptor 22.7.10.10.445
2wxvWXVCyclin-dependent kinase 22.7.11.220.445
3bqr4RBDeath-associated protein kinase 3/0.445
3iok1P6Tyrosine-protein kinase JAK2/0.445
3rpy27ZCyclin-dependent kinase 22.7.11.220.445
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.445
3unj0BXCyclin-dependent kinase 22.7.11.220.445
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4dymIYZActivin receptor type-12.7.11.300.445
4gu610NFocal adhesion kinase 12.7.10.20.445
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1pmn984Mitogen-activated protein kinase 102.7.11.240.444
2ojj82AMitogen-activated protein kinase 12.7.11.240.444
2pvnP63Casein kinase II subunit alpha2.7.11.10.444
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.444
2x6dX6DAurora kinase A2.7.11.10.444
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.444
2xmyCDKCyclin-dependent kinase 22.7.11.220.444
2zjwREFCasein kinase II subunit alpha2.7.11.10.444
3gxlQIGTGF-beta receptor type-12.7.11.300.444
3my5RFZCyclin-dependent kinase 22.7.11.220.444
3qa2XNAKetohexokinase/0.444
3ttjJBIMitogen-activated protein kinase 102.7.11.240.444
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fko20KCyclin-dependent kinase 22.7.11.220.444
4ocgFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.444
1gih1PUCyclin-dependent kinase 22.7.11.220.443
1h5rTHMGlucose-1-phosphate thymidylyltransferase 1/0.443
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
1y91CT9Cyclin-dependent kinase 22.7.11.220.443
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.443
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2r5q1UNGag-Pol polyprotein/0.443
2vd5BI8Myotonin-protein kinase2.7.11.10.443
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.443
3q5iANPProtein kinase, putative/0.443
3vhkBPKVascular endothelial growth factor receptor 22.7.10.10.443
4deeADPAurora kinase A2.7.11.10.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.443
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.443
1vjy460TGF-beta receptor type-12.7.11.300.442
2gstGPSGlutathione S-transferase Mu 12.5.1.180.442
2pmoHMDProtein kinase 7/0.442
2pwcG3GGag-Pol polyprotein3.4.23.160.442
2w1hL0FCyclin-dependent kinase 22.7.11.220.442
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.442
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.442
3hx4ANPCalmodulin-domain protein kinase 1/0.442
3k5uPFQAurora kinase A2.7.11.10.442
3vn9ANKDual specificity mitogen-activated protein kinase kinase 62.7.12.20.442
4c3pACPAurora kinase A2.7.11.10.442
4i22IREEpidermal growth factor receptor2.7.10.10.442
4wsqKSAAP2-associated protein kinase 12.7.11.10.442
1meiXMPInosine-5'-monophosphate dehydrogenase/0.441
1p4fDRGDeath-associated protein kinase 12.7.11.10.441
1sduMK1Gag-Pol polyprotein3.4.23.160.441
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.441
2fxdDR7Pol polyprotein/0.441
2r3lSCWCyclin-dependent kinase 22.7.11.220.441
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.441
3ictFADCoenzyme A disulfide reductase/0.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3orlAGSSerine/threonine protein kinase/0.441
3ral04ZCyclin-dependent kinase 22.7.11.220.441
3vt7VDXVitamin D3 receptor/0.441
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.441
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.441
4c62XWWTyrosine-protein kinase JAK2/0.441
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gk3L87Ephrin type-A receptor 32.7.10.10.441
4zohFADPutative oxidoreductase FAD-binding subunit/0.441
1mp8ADPFocal adhesion kinase 12.7.10.20.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1sn0T44Transthyretin/0.440
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2itpAEEEpidermal growth factor receptor2.7.10.10.440
2jkoBIJFocal adhesion kinase 12.7.10.20.440
3kfs3TLGag-Pol polyprotein/0.440
3lpbNVBTyrosine-protein kinase JAK2/0.440
3rvg17PTyrosine-protein kinase JAK2/0.440
3sw719KCyclin-dependent kinase 22.7.11.220.440
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.440
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.440
3ufnROCGag-Pol polyprotein/0.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3zxtACPDeath-associated protein kinase 12.7.11.10.440
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4aua4AUCyclin-dependent kinase 62.7.11.220.440
4fz70VHTyrosine-protein kinase SYK2.7.10.20.440
4gg70J8Hepatocyte growth factor receptor2.7.10.10.440
4h3qANPMitogen-activated protein kinase 12.7.11.240.440
4j95ACPFibroblast growth factor receptor 2/0.440
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.440
4qmlANPSerine/threonine-protein kinase 242.7.11.10.440