sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2c97	JCL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2c97	JCL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	1.000
2c92	TP6	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.576
1w29	TS1	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.530
1w19	T4P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.529
1w29	TS0	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.520
2c9d	PHR	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.517
1w19	T5P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.512
1rvv	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.511
2c9b	PUG	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.471
1nqx	RLP	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.469
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.468
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.445
2vi5	Y19	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.445