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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c6lDT4Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c6lDT4Cyclin-dependent kinase 22.7.11.221.000
1y8yCT7Cyclin-dependent kinase 22.7.11.220.536
1w8cN69Cyclin-dependent kinase 22.7.11.220.533
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.526
3r8vZ62Cyclin-dependent kinase 22.7.11.220.516
2c6iDT1Cyclin-dependent kinase 22.7.11.220.514
4fklCK2Cyclin-dependent kinase 22.7.11.220.509
2r3jSCJCyclin-dependent kinase 22.7.11.220.505
3lfqA28Cyclin-dependent kinase 22.7.11.220.502
3r83Z14Cyclin-dependent kinase 22.7.11.220.502
2vtsLZCCyclin-dependent kinase 22.7.11.220.501
3rahO1ZCyclin-dependent kinase 22.7.11.220.497
1oitHDTCyclin-dependent kinase 22.7.11.220.492
3r8lZ30Cyclin-dependent kinase 22.7.11.220.490
2a0cCK9Cyclin-dependent kinase 22.7.11.220.489
3s1h56ZCyclin-dependent kinase 22.7.11.220.488
1pxoCK7Cyclin-dependent kinase 22.7.11.220.487
2r3iSCFCyclin-dependent kinase 22.7.11.220.483
3r7yZ04Cyclin-dependent kinase 22.7.11.220.483
4ek610KCyclin-dependent kinase 22.7.11.220.481
1ykr628Cyclin-dependent kinase 22.7.11.220.480
2c6kDT2Cyclin-dependent kinase 22.7.11.220.477
3r9nZ68Cyclin-dependent kinase 22.7.11.220.477
3r7uX96Cyclin-dependent kinase 22.7.11.220.475
1pxmCK5Cyclin-dependent kinase 22.7.11.220.474
2vv9IM9Cyclin-dependent kinase 22.7.11.220.472
4fkt48KCyclin-dependent kinase 22.7.11.220.472
3rak03ZCyclin-dependent kinase 22.7.11.220.471
2btsU32Cyclin-dependent kinase 22.7.11.220.470
2c6o4SPCyclin-dependent kinase 22.7.11.220.469
3rkb12ZCyclin-dependent kinase 22.7.11.220.466
3qqlX03Cyclin-dependent kinase 22.7.11.220.463
3sw719KCyclin-dependent kinase 22.7.11.220.462
2b53D23Cyclin-dependent kinase 22.7.11.220.460
3lfnA27Cyclin-dependent kinase 22.7.11.220.460
1pxlCK4Cyclin-dependent kinase 22.7.11.220.459
3fz1B98Cyclin-dependent kinase 22.7.11.220.459
4fkq42KCyclin-dependent kinase 22.7.11.220.459
1oirHDYCyclin-dependent kinase 22.7.11.220.457
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.454
2w17I19Cyclin-dependent kinase 22.7.11.220.451
3r1yX76Cyclin-dependent kinase 22.7.11.220.450
3r71X86Cyclin-dependent kinase 22.7.11.220.450
3wblPDYCyclin-dependent kinase 22.7.11.220.449
3r7vZ02Cyclin-dependent kinase 22.7.11.220.448
1gii1PUCyclin-dependent kinase 22.7.11.220.447
1ke5LS1Cyclin-dependent kinase 22.7.11.220.447
2r3p3SCCyclin-dependent kinase 22.7.11.220.446
3ezvEZVCyclin-dependent kinase 22.7.11.220.444
3qtsX46Cyclin-dependent kinase 22.7.11.220.444
3qzgX67Cyclin-dependent kinase 22.7.11.220.444
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.442
2uzoC62Cyclin-dependent kinase 22.7.11.220.441
1y91CT9Cyclin-dependent kinase 22.7.11.220.440
4fkg4CKCyclin-dependent kinase 22.7.11.220.440